KEGG   Rhinopithecus bieti (black snub-nosed monkey): 108532286
Entry
108532286         CDS       T04641                                 
Symbol
FGFR3
Name
(RefSeq) LOW QUALITY PROTEIN: fibroblast growth factor receptor 3
  KO
K05094  fibroblast growth factor receptor 3 [EC:2.7.10.1]
Organism
rbb  Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb01521  EGFR tyrosine kinase inhibitor resistance
rbb04010  MAPK signaling pathway
rbb04014  Ras signaling pathway
rbb04015  Rap1 signaling pathway
rbb04020  Calcium signaling pathway
rbb04144  Endocytosis
rbb04151  PI3K-Akt signaling pathway
rbb04550  Signaling pathways regulating pluripotency of stem cells
rbb04810  Regulation of actin cytoskeleton
rbb05200  Pathways in cancer
rbb05206  MicroRNAs in cancer
rbb05219  Bladder cancer
rbb05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:rbb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    108532286 (FGFR3)
   04014 Ras signaling pathway
    108532286 (FGFR3)
   04015 Rap1 signaling pathway
    108532286 (FGFR3)
   04020 Calcium signaling pathway
    108532286 (FGFR3)
   04151 PI3K-Akt signaling pathway
    108532286 (FGFR3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    108532286 (FGFR3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    108532286 (FGFR3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    108532286 (FGFR3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    108532286 (FGFR3)
   05206 MicroRNAs in cancer
    108532286 (FGFR3)
   05230 Central carbon metabolism in cancer
    108532286 (FGFR3)
  09162 Cancer: specific types
   05219 Bladder cancer
    108532286 (FGFR3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    108532286 (FGFR3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rbb01001]
    108532286 (FGFR3)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:rbb04090]
    108532286 (FGFR3)
Enzymes [BR:rbb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     108532286 (FGFR3)
Protein kinases [BR:rbb01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   108532286 (FGFR3)
CD molecules [BR:rbb04090]
 Proteins
  108532286 (FGFR3)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set Ig_3 ig Ig_2 FGFR3_TM V-set C2-set_2 ABC1 Pkinase_fungal
Other DBs
NCBI-GeneID: 108532286
NCBI-ProteinID: XP_017731720
LinkDB
Position
Unknown
AA seq 809 aa
MGPACASALCRGSGHRGRRPPRSLGDEQRVVGRVAEVPGPEPSQQEQLVFGSGDTVELSC
LPPGGGPMGPTVWVKDGAGLVPSERVLVGPQLLQVLNASHEDSGAYSCRQRLTQRVLCHF
SVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGN
PTPSISWLKNGKEFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTY
TLDVLERSPHRPILLFVLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPD
GTPYVTVLKSWISESVEADVRLRLANVSERDGGEYLCRATNFIGVAEKAFWLSVHGPRAA
EEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSTPKKGLGSPTVHKISRFPL
KRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLG
EGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNII
NLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAY
QVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVK
WMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANC
THDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPA
PASSRAQEMNSAAHDLLPPAPPSSGGSRT
NT seq 2430 nt   +upstreamnt  +downstreamnt
atgggccctgcctgcgcctcagctctctgccgtggcagtggccatcgtggccggcggcct
cctcggagtcttggggacgagcagcgcgtcgtggggcgagtggcagaagtccccggccca
gagcccagccagcaggagcagttggtcttcggcagcggggacactgtggagctgagctgt
ctcccgcccgggggtggtcccatggggcccactgtctgggtcaaggatggcgcagggctg
gtgccctcggagcgtgtcctggtggggccccagctgctgcaggtgctgaatgcctcccac
gaggactctggggcctacagctgccggcagcgactcacacagcgcgtactttgccacttc
agtgtgcgggtgacagacgctccatcctcgggagatgacgaagacggagaggacgaggct
gaggacacaggtgtggacacaggggccccttactggactcggcctgagcggatggacaag
aagctgctggccgtgccagccgccaacaccgtccgcttccgctgcccggctgctggtaac
cccactccctccatctcctggctgaagaatggcaaggagttccgcggcgagcaccgcatc
ggaggcatcaagctgcggcaccagcagtggagcctggtcatggaaagtgtggtgccctcg
gaccgcggcaactacacctgcgtggtggagaacaagtttggcagcatccggcagacatac
acactggacgtgctggagcgctccccgcaccggcccatcctgctttttgtgctgccggcc
aaccagacggcggtgctgggcagcgatgtggagtttcactgcaaggtgtacagtgacgcg
cagccccacatccagtggctcaagcacgtggaggtgaatggcagcaaggtgggccccgac
ggcacaccctacgtcaccgtgctcaagtcctggatcagtgagagtgtggaggccgacgtg
cgcctccgcctggccaatgtgtcggagcgggacgggggcgagtacctctgtcgagccacc
aatttcataggcgtggccgagaaggccttttggctgagcgttcacgggccccgagcagcc
gaggaggagctggtggaggctgacgaggcgggcagtgtgtacgcaggcatcctcagctac
ggggtgggcttcttcctgttcatcctggtggtggcggctgtgacgctctgccgcctgcgc
agcacccccaagaaaggcctgggctcccccaccgtgcacaagatctcccgcttcccactc
aagcgacaggtgtccctggagtccaacgcgtccatgagttccaacacaccgctggtgcgc
atcgcaaggctgtcctcaggggagggtcccacgctggccaatgtctctgagcttgagctg
cctgctgaccccaaatgggagctgtctcgggcccggctgaccctgggtaagccccttggg
gagggctgcttcggccaggtggtcatggcggaggctatcggcattgacaaggaccgggcc
gccaagcctgtcaccgtagccgtgaagatgctgaaagatgatgccactgacaaggacctg
tcagacctggtgtctgagatggagatgatgaagatgattgggaaacacaagaacatcatc
aacctgctgggcgcctgcacgcagggcgggcccctgtacgtgctggtggagtatgcggcc
aagggcaacctgcgggagtttctgcgggcgcggcggcccccgggcctggactactccttc
gatacttgcaagccgcctgaggagcagctcaccttcaaggacctggtgtcctgtgcctac
caggtggcccgaggcatggagtacctcgcctcccagaagtgcatccaccgggacctggct
gctcgaaacgtgctggtgaccgaggacaacgtgatgaagatcgcagacttcgggctggcc
cgcgacgtgcacaacctcgactactacaagaagaccaccaacggccggctgcccgtgaag
tggatggcgcctgaggccctgtttgaccgcgtctacacccaccagagtgacgtctggtcc
tttggggtcctgctctgggagatcttcacgctggggggctctccataccccggcatccct
gtggaggagctcttcaagctactgaaggagggccaccgaatggacaagccggccaactgc
acacacgacctgtacatgatcatgcgggagtgctggcatgctgcgccctcccagaggccc
accttcaagcagctggtggaggacctggaccgtgtcctcactgtgacgtccaccgacgag
tacctggacctgtcagcgcccttcgagcagtactcccccggcggccaggacaccccagct
ccagcctccagccgcgctcaggagatgaactccgctgcccacgacctgctgcccccggcc
ccacccagcagtgggggctcgcggacgtga

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