Rhinopithecus bieti (black snub-nosed monkey): 108534230
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Entry
108534230 CDS
T04641
Symbol
JAK3
Name
(RefSeq) tyrosine-protein kinase JAK3 isoform X1
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
rbb
Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb04062
Chemokine signaling pathway
rbb04151
PI3K-Akt signaling pathway
rbb04217
Necroptosis
rbb04550
Signaling pathways regulating pluripotency of stem cells
rbb04630
JAK-STAT signaling pathway
rbb04658
Th1 and Th2 cell differentiation
rbb04659
Th17 cell differentiation
rbb05161
Hepatitis B
rbb05162
Measles
rbb05166
Human T-cell leukemia virus 1 infection
rbb05169
Epstein-Barr virus infection
rbb05200
Pathways in cancer
rbb05203
Viral carcinogenesis
rbb05223
Non-small cell lung cancer
rbb05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
rbb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
108534230 (JAK3)
04151 PI3K-Akt signaling pathway
108534230 (JAK3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
108534230 (JAK3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
108534230 (JAK3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
108534230 (JAK3)
04659 Th17 cell differentiation
108534230 (JAK3)
04062 Chemokine signaling pathway
108534230 (JAK3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
108534230 (JAK3)
05203 Viral carcinogenesis
108534230 (JAK3)
09162 Cancer: specific types
05223 Non-small cell lung cancer
108534230 (JAK3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
108534230 (JAK3)
05161 Hepatitis B
108534230 (JAK3)
05162 Measles
108534230 (JAK3)
05169 Epstein-Barr virus infection
108534230 (JAK3)
09163 Immune disease
05340 Primary immunodeficiency
108534230 (JAK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rbb01001
]
108534230 (JAK3)
Enzymes [BR:
rbb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
108534230 (JAK3)
Protein kinases [BR:
rbb01001
]
Non-receptor tyrosine kinases
JAK family [OT]
108534230 (JAK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
SH2_1
FERM_F1
Jak1_Phl
SH2
ABC1
Kinase-like
Kdo
FERM_C_FAK1
LRR_RI_capping
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
108534230
NCBI-ProteinID:
XP_017734969
LinkDB
All DBs
Position
Unknown
AA seq
1205 aa
AA seq
DB search
MTVAQETKGPTQEGAEWDFPLAASRLCSPFEGPGSLPARAKLGIISLWETRGFSKVPGTR
NVLILGLGIGDIKVSLWQVALMAPPSEETPLIPQRSCSLLSTEAGALHVLLPARGPGPPQ
RLSFSFGDHLAEDLCVQAAKASGILPVYHSLFALATEDLSCWFPPSHIFSVEDASTQVLL
YRIRFYFPNWFGLDKCHRFGLRKDLASAILDLPVLEHLFAQHRSDLVSGRLPVGLSLKEQ
GECLSLAVLDLARMAREQAQRPGELLKTVSYKACLPPSLRDLIQGLSFVTRRRIRRTVRR
ALRRVAACQADRHSLMAKYIMDLERLDPAGAAETFHVGLPGVPGGQDGMGLLRVAGDGGI
AWTQGEQEVLQPFCDFPEIVDISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPEAL
SFVALVDGYFRLTTDSQHFFCKEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSRPGSY
VLRRSPQDFDSFLLTVCVQSPLGPDYKGCLIQRSPTGTFFLVGLSRSHSSLRELLAACWD
GRLHVDGVAVTLTSCCIPRPKEKSNLIVVQRGCSPPTSSLVQPQSQCQLSQMTFHKIPAD
SLEWHENLGHGSFTKIYRGCRHEAVDGESRKTEVLLKVMDAKHKNCMESFLEAASLMSQV
SYRHLVLLHGVCMAGDSTMVQEFVHLGAIDMYLRKRGHLVPASWKLQVVKQLAYALNYLE
DKGLPHGNVSARKVLLAREGADGSPPFIKLSDPGVSPAVLSLEMLTDRIPWVAPECLREA
QTLNLEADKWGFGATVWEVFSGVTMPISALDPAKKLQFYEDRQQLPAPKWTELALLIQQC
MAYEPVQRPSFRAVIRDLNSLISSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEE
RHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALH
SDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEY
LGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESL
SDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMGCERDVPALCLLLELLEEGQR
LPAPPACPAEVHELMKLCWAPSPQDRPSFSTLGPQLDVLWSGSRGCETHAFTAHPEGKPH
SLSFL
NT seq
3618 nt
NT seq
+upstream
nt +downstream
nt
atgacagtggctcaggaaaccaaggggcccacacaggaaggagccgagtgggactttcct
ctcgctgcctcccggctctgctctcccttcgaaggcccagggtccctgcctgctagggca
aaactaggcatcatctctctttgggagacaaggggcttctccaaggttcctgggacgagg
aatgtgctcattcttggtctgggcattggtgacatcaaagtgtccctttggcaagttgca
ctcatggcacctccaagtgaggagacacccctgatccctcagcgctcctgcagcctcttg
tccacggaggctggtgccctgcacgtgctactgcccgctcggggccccgggcccccccag
cgcctatctttctcctttggggaccacttggctgaagacctgtgcgtgcaggctgccaag
gccagcggcatcctgcctgtgtaccactccctctttgctctggccacggaggacctgtcc
tgctggttccccccgagccacatcttctccgtggaggatgccagcacccaagtcctgctc
tacaggattcgcttttacttccccaattggtttgggctggacaagtgccaccgcttcggg
ctacgcaaggatttggccagcgctatccttgacctgccagtcctggagcacctctttgcc
cagcaccgcagtgacctggtgagtgggcgcctccctgtgggcctcagcctcaaggagcag
ggtgagtgtctcagcctggccgtgctggacctggcccggatggcgcgagagcaggcccag
cggccaggagagctgctgaagactgtcagctacaaggcctgcctacccccaagcctgcgc
gacctgatccagggcctgagtttcgtgacgcggaggcgtattcggaggacagtgcgcagg
gccctgcgccgcgtggccgcctgccaggccgaccggcactcgctcatggccaagtacatt
atggatctggagcggctggatccggctggggccgccgagaccttccatgtgggcctccct
ggggtccctggtggccaggacgggatggggctgctccgcgtggctggtgacggaggcatc
gcctggacccagggagaacaggaggtcctccagcccttctgcgactttccagaaatcgta
gacattagcatcaagcaggccccgcgcgttggcccggccggggagcaccgcctggtcact
gtcaccaggacagacaaccagattttggaggccgagttcccggggctgcccgaggctctg
tctttcgtggcgctcgtggacggctacttccggctgaccacggactcccagcacttcttc
tgcaaggaggtggcaccgccgaggctgctggaggaggtggcagagcagtgccacggcccc
atcactctggactttgccataaacaagcttaagactgggggctcacgtcctggctcctat
gttctccgccgcagcccccaggactttgacagcttcctcctcactgtctgtgtacagagc
ccccttggtcctgattataagggttgcctcattcagcgcagccccacagggaccttcttt
ctggttggcctcagccgatcccacagcagccttcgagagctcctggcagcctgctgggat
gggaggctgcacgtagatggggttgcagtgaccctcacctcctgctgtatccccagaccc
aaagaaaagtccaacttgatcgtggtccagagaggttgcagcccacccacgtcctccctg
gttcagccccaatcccaatgtcagctgagtcagatgacatttcacaagatccccgctgac
agcctagagtggcatgagaacctgggccatgggtccttcaccaagatttaccggggctgt
cgccacgaggcggtggatggggagtcccgaaagacagaggtgctgctaaaagtgatggat
gctaagcacaagaactgcatggagtcattcctggaagcagcgagcttgatgagccaagtg
tcgtaccggcatctcgtgctgctccacggcgtgtgcatggctggagacagcaccatggtg
caagaatttgtacacctgggggcgatagacatgtatctgcgaaaacgtggccacctggtg
ccagccagctggaagctgcaggtggtcaaacagctggcctatgccctcaactatctggag
gacaaaggcctcccccacggcaatgtctccgcccggaaggtgctcttggctcgggagggg
gctgatgggagcccacccttcatcaagctgagtgaccctggggtcagccccgctgtgtta
agcctggagatgctcaccgacaggatcccctgggtggctcccgagtgtcttcgggaggcc
cagacacttaacttggaagctgacaagtggggcttcggtgccacggtctgggaggtgttt
agtggcgtcaccatgcccatcagcgccctggatcctgctaagaaactccaattttatgag
gaccggcagcagctgccggcccccaagtggacagagctggccctgctgattcaacagtgc
atggcctatgagccggtccagaggccctccttccgagccgtcattcgtgacctcaacagc
ctcatctcttcagactatgagctcctctcagaccccacacctggtgccctggcacctcgt
gatgggctgtggaatggtgcccagctctatgcctgccaagaccccacgatcttcgaggag
agacacctcaagtacatctcacagctgggcaagggcaactttggcagtgtggagctgtgc
cgctatgacccgctaggcgacaacacaggtgctctggtggccgtgaaacagctgcagcac
agcgggccagaccagcagagggacttccagcgggagattcagatcctcaaagcactgcac
agtgatttcattgtcaagtatcgtggtgtcagctatggcccgggccgccagagcctgcgg
ctggtcatggagtacctgcccagcggctgcttgcgcgacttcctgcagcggcaccgcgcg
cgcctcgatgccagccgcctccttctctactcctcgcagatctgcaagggcatggagtac
ctgggctcccgccgctgcgtgcaccgcgacctggccgcccgaaacatcctggtggagagc
gaggcccacgtcaagatcgctgacttcggcctagctaagctgctgccgcttgacaaagac
tactacgtggtccgcgagccgggccagagccccattttctggtatgcccccgaatccctc
tcggacaacatcttctctcgccagtcagacgtctggagcttcggggtcgtcctgtacgag
ctcttcacctactgtgacaaaagctgcagcccctcggccgagtttctgcggatgatggga
tgtgagcgggatgtccccgccctctgccttctcttggaactgctggaggagggccagagg
ctgccggcgcctcctgcctgccctgctgaggttcacgagctcatgaagctgtgctgggcc
cctagcccacaggaccggccatcattcagcaccctgggcccccagctggacgtgctgtgg
agcggaagccgggggtgtgagactcacgccttcactgctcacccagagggcaaaccacac
tccctgtcctttttatag
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