Cupriavidus necator H16: H16_B1300
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Entry
H16_B1300 CDS
T00416
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase complex, dehydrogenase (E1) component (lipoamide)
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
reh
Cupriavidus necator H16
Pathway
reh00010
Glycolysis / Gluconeogenesis
reh00020
Citrate cycle (TCA cycle)
reh00620
Pyruvate metabolism
reh00785
Lipoic acid metabolism
reh01100
Metabolic pathways
reh01110
Biosynthesis of secondary metabolites
reh01120
Microbial metabolism in diverse environments
reh01200
Carbon metabolism
reh01210
2-Oxocarboxylic acid metabolism
Module
reh_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
reh00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
H16_B1300 (aceE)
00020 Citrate cycle (TCA cycle)
H16_B1300 (aceE)
00620 Pyruvate metabolism
H16_B1300 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
H16_B1300 (aceE)
Enzymes [BR:
reh01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
H16_B1300 (aceE)
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Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF3135
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
CAJ96090
UniProt:
Q0K1N4
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Position
2:1455029..1457725
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AA seq
898 aa
AA seq
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MTDLASPHARLLAQAMPDGDDDPQETREWLDALEAVVAQCGQERARFLLGRLLDAAPALG
VSTTAQSNTPYLNTIPVECQPPYPGDLAMEERITGIVRWNALAMVVRANQAYGELGGHIS
SYASAADLFEVGFNHFFQGADAGNGGDLVYFQPHSAPGVYARAFLEGRLSEAQLDNFRRE
AGGQGLCSYPHPWLMPDFWQFPTGSMGLGPIQSVYQARFMRYMEHRGLQATSGRHVWGVF
GDGEMDEPESIAALPLAAREKLDNLTFVINCNLQRLDGPVRGNGQIVQELEALFRGAGWN
VIKVLWGSAWDPIFARDHSGALLRAFASTMDGQFQTYKAKDGHYGREHFFGQNEALKALV
AHMTPDEVAALNRGGHDLRKLHAAFAAARAHKGQPTVILAKTIKGYGMGNAGQAQNTTHQ
QKKLDIEALKAFRSRFGLELSDEDLESMRFYRPAEDSAELRYLRERRQVLGGYLPARQRQ
ADTVAVPPLAQYGQFAVAADQKEMSTTMAMVRMLTGLLKDKALGPRVVPIVADEARTFGM
ASLFRQVGIYSSQGQLYEPEDAGSMLYYREDIRGQILEEGITEAGAMSSWIAAGTAYSNH
GTAMLPLYIYYSMFGFQRIGDLIWAAGDQRARGFLVGATAGRTTLSGEGLKHQDGTSHII
AATIPNCRAYDPAYAYELAVIVDEGMRAMMERQEDVFYYLTVMNENYAQPSMPAGVERDI
VRGMYRLAQVEGGGRARVRLLGSGTILREVEAAAQMLAEDWQVDSEVFSVTSFSELEREA
RETARQRLHHPQDSIAPSHVEALLAGDAPVVAATDYVRAYPQLIAPYVPAPFTVLGTDGY
GRSDNRPSLRRFFEVDRAYVCVAALRALAAQGTVPASVVAEAITRYGIDTDKPAPSSL
NT seq
2697 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccttgcctccccacacgcccgcctgctcgcccaggccatgcccgacggcgac
gacgatccgcaggagacgcgcgaatggctggacgcgctggaggcagtggtggcgcaatgc
gggcaggagcgcgcgcgcttcctgctcggccggctgctcgatgccgcccccgcgctgggt
gtgtcgaccacggctcagagcaacacgccttacctgaacaccatcccggtcgagtgccag
ccgccttatccgggggatctggcgatggaagagcgcatcaccggcatcgtgcgctggaat
gcccttgccatggtggtgcgcgccaaccaggcctacggtgaactgggcgggcatatctcc
agctatgcctcggcggcggacctgttcgaggtcggcttcaaccacttcttccagggcgcc
gatgccggcaacggcggcgacctggtctacttccagccgcactcggccccgggcgtgtac
gcgcgcgccttcctggaaggacgcctgtccgaggcccagctcgacaacttccgccgcgag
gcgggggggcagggcctgtgctcgtatccgcacccctggctgatgccggacttctggcag
ttcccgaccggctcgatggggctgggcccgatccagtcggtctaccaggcgcgcttcatg
cgctacatggagcaccgggggctgcaggccacttcgggccggcacgtgtggggcgtgttc
ggcgacggcgagatggacgagcccgaatcgatcgccgcgctgccgctggcagcgcgcgag
aagctcgacaacctgacctttgtcatcaactgcaacctgcagcgcctggacggcccggtg
cgcggcaacggccagatcgtgcaggagctggaagcgctgttccgcggcgcgggctggaac
gtgatcaaggtgctgtggggcagcgcctgggacccgatcttcgcgcgcgatcactccggc
gcgttgctgcgcgccttcgcctcgaccatggacggccagttccagacttacaaggccaag
gacggccactatgggcgcgagcatttctttggccagaacgaagcgctgaaggcactggtc
gcgcatatgacgccggatgaggtggcggcgctgaaccgcggcggacacgacctgcgcaag
ctccatgcggcctttgccgcggcacgcgcgcacaagggccagcccacggtgatcctggcc
aagaccatcaagggctatggcatgggcaatgccggccaggcgcagaacaccacgcaccag
cagaagaagctcgacatcgaggcgctgaaggcattccgcagccgcttcggcctggagctg
tccgacgaggacctggaatcgatgcgcttctaccgcccggccgaggacagcgctgagctg
cgctacctgcgcgaacgccgccaggtgctgggcggctacctgccggcgcgccagcgccag
gccgacaccgtggcggtgccgccgctggcgcaatacggccagttcgcggtggcggccgac
cagaaggagatgtcgaccaccatggcaatggtgcgcatgctgaccggcctgctcaaggac
aaggcgctcggtccgcgcgtggtgcccatcgtcgccgacgaggcgcgcaccttcggcatg
gccagcctgttccgccaggtcggcatctattcatcgcagggccagctgtacgagcccgag
gacgccggctcgatgctgtactaccgcgaggacatccgcggccagatcctggaagagggc
atcaccgaggccggtgcgatgtcgtcgtggattgccgcgggcaccgcctacagcaaccat
ggcacggccatgctgccgctctatatctactactcgatgttcggcttccagcgcatcggc
gacctgatctgggccgccggcgaccagcgtgcgcgcggcttcctggtgggcgctacggca
ggccgcaccacgctgtccggcgaagggctgaagcaccaggacggcaccagccacatcatt
gccgccaccatccccaactgccgcgcctatgaccccgcctacgcctatgagctggcagtc
atcgtcgacgagggcatgcgcgcgatgatggagcgccaggaggacgtgttctattacctg
accgtgatgaacgagaactacgcccagccgtcgatgccggcgggcgtggagcgcgacatc
gtgcgcggcatgtaccggcttgcgcaggtggaaggcggcgggcgcgccagggtgcggctg
ctcggcagcggcaccatcctgcgcgaggtggaggccgcggcgcagatgctggccgaggac
tggcaggtcgacagcgaggtgttcagcgtcaccagcttctccgagctggagcgcgaggcg
cgcgagaccgcgcgccagcgcctgcatcatccgcaggacagcatcgcccccagccatgtg
gaagcgctgctggccggcgacgcgccggtggtggcggccactgactacgtgcgcgcctat
ccgcagctgattgcgccctacgtgccggctcccttcacggtgctgggcaccgacggctat
ggccgcagcgacaaccggccgtcgctgcgccgcttcttcgaggtcgatcgcgcctatgtc
tgcgtggcggcgctgcgcgcgcttgcggcgcagggcacggtgccggcgtcggtggtggcc
gaggcgatcacgcgctacggcatcgacacggacaagcctgcgccgtcctcgctctga
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