Prescottella equi: REQ_23110
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Entry
REQ_23110 CDS
T01352
Symbol
metH
Name
(GenBank) methionine synthase MetH
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
req
Prescottella equi
Pathway
req00270
Cysteine and methionine metabolism
req00450
Selenocompound metabolism
req00670
One carbon pool by folate
req01100
Metabolic pathways
req01110
Biosynthesis of secondary metabolites
req01230
Biosynthesis of amino acids
req04980
Cobalamin transport and metabolism
req04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
req00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
REQ_23110 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
REQ_23110 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
REQ_23110 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
REQ_23110 (metH)
04980 Cobalamin transport and metabolism
REQ_23110 (metH)
Enzymes [BR:
req01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
REQ_23110 (metH)
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Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding
B12-binding_2
CdhD
Senescence_reg
Motif
Other DBs
NCBI-ProteinID:
CBH48357
UniProt:
A0A3S5Y743
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Position
2436376..2439954
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AA seq
1192 aa
AA seq
DB search
MDGMSAPFHSALLDALKQRVVIGDGAMGTMLQAADLTLDDFLGLEGCNEILNETRPDVLR
DIHRAYFEAGADAVETNTFGCNLPNLADYDIAHRIRDLSERGTRIAREVADEMGPGRDGM
GRFVLGSMGPGTKLPTLGHAPFAVLRDAYTESALGMIEGGADAILVETCQDLLQVKAAII
GSQHAMEKLGRRLPIITHVTVETTGTMLLGSEIGAALTALEPLGIDMIGLNCATGPDEMS
EHLRHLSRHSKLPVSVMPNAGLPQLGPNGAEYPLSAEELAVALSGFVSEFGLSFVGGCCG
TTPEHIRQVADAVRRVEQAKRTPEPEDGTSSLYQAVPFDQDASILMIGERTNSNGSKAFR
EAMIAEDYQKCIDIAKDQTRDGAHMLDLNVDYVGRDGAADMAALASRFATASTLPIMLDS
TEPEVLRAGLEHLGGRCAVNSVNYEDGDGPNSRYQRIMKLVKEHGAAVVALTIDEEGQAR
TAEHKVRIAERLIQDITTTWGLSQSDIIIDALTFPISTGQEEVRRDGIETIEAIREIKRR
YPDVHFTLGISNISFGLNPAARQVLNSVFLHECTEAGLDTAIVHASKILPMARIPDEQRE
TALDLVYDRRREGYDPLQKLMELFEGVSAASARESRAEELAALPLFERLERRIVDGERNG
LEADLDAAMVERPPLEIINETLLSGMKTVGELFGSGQMQLPFVLQSAEVMKAAVAYLEPH
MESTGDEGKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNIGIKQPIATILDVALDKK
ADVIGMSGLLVKSTVVMKENLEELNAKGVAEQFPVLLGGAALTRSYVENDLSDVYQGEVS
YARDAFEGLHLMDTIMAVKRGEGPAPDSPEAIAAAEKAAERKARHERSKRIAEKRKAESA
PVEVPERSDVAADIVVPTPPFWGTRIVKGIALAEYSGLLDERALFLGQWGLRGQRAGDGP
TYEELVETEGRPRLRYWLDRLSTEGVLQHAAVVYGYFPAVSEGDDVIVLESPDPDAPERF
RFTFPRQQRDRFLCIADFVRSRDDARKDGQVDVLPMNLVTMGQPIADFANELFAANSYRD
YLEVHGIGVQLTEALAEYWHRRVREELVLPGGHNLAEQDPSDVEDFFKLEYRGARYSFGY
GACPDLEDRRKLVALLEPERIGVELSEEVQLHPEQSTDAFVLHHPEAKYFNV
NT seq
3579 nt
NT seq
+upstream
nt +downstream
nt
gtggacggcatgtctgcaccattccactctgccctgctcgatgcgctgaagcagcgcgtt
gtcatcggcgacggcgccatgggcacgatgttgcaggccgcggatctgactctcgacgac
ttcctcgggctcgaaggctgcaacgagattctcaacgagacccgtcccgacgtgctgcgc
gacatccaccgcgcgtacttcgaggccggcgccgacgcggtcgaaaccaacactttcggt
tgcaacctcccgaacctcgccgactacgacatcgcccaccgcatccgggacctgtccgag
cgcggtacccggatcgcccgcgaggtcgcggacgagatgggtcccggccgcgacggcatg
ggccggttcgtgctcggctcgatgggtccgggcaccaagctgcccaccctcggccacgcc
ccgttcgcggtcctgcgtgacgcctacaccgagtctgcgctcggcatgatcgaggggggc
gccgacgcgatcctcgtcgagacctgccaggacctgctccaggtgaaggctgcgatcatc
ggcagccagcacgcgatggagaagctggggcgccgcctgccgatcatcacccacgtcacg
gtcgagacgaccggcacgatgctgctcggcagcgagatcggcgccgcgctcacggcgctc
gagccgctcggcatcgacatgatcggcctcaactgcgccaccggcccggacgagatgagc
gagcacctgcggcacctgtcgcggcactcgaagctgccggtgtccgtgatgccgaacgcc
ggtctgccgcagctgggtccgaacggggccgagtacccgctgtcggccgaggaactcgcg
gtcgcgctgtcgggcttcgtgagcgagttcggtctgtcgttcgtcggtggctgctgcggc
accacccccgagcacatccgtcaggtcgccgacgccgtccgccgggtcgagcaggcgaag
cgcacgccggagcccgaggacgggacgtcgtcgctgtaccaggcggtgccgttcgatcag
gacgcctcgatcctgatgatcggtgagcggacgaactccaacggctccaaggcgttccgc
gaggccatgatcgccgaggactaccagaagtgcatcgacatcgcgaaggaccagacccgc
gacggcgcgcacatgctcgacctcaacgtcgactacgtcggtcgtgacggcgccgccgac
atggctgcgctcgcaagccgattcgcgaccgcgtcgacgctgccgatcatgctcgactcc
accgagcccgaggtgctccgcgccgggctcgagcatctcggcggccgctgcgccgtcaac
tcggtgaactacgaggacggcgacggcccgaactcgcgctaccagcgaatcatgaagctg
gtcaaggaacacggcgcagcggtcgtggcgctcacgatcgacgaggagggccaggcccgc
accgccgagcacaaggtccggatcgccgagcggttgatccaggacatcaccaccacgtgg
ggcctgtcgcagtcggacatcatcatcgacgcgttgacgttcccgatctcgacggggcag
gaggaggtccgccgcgacggcatcgagaccatcgaggcgatccgcgagatcaaacgccgc
tacccggacgtgcacttcacgctcggtatctcgaacatctcgttcggcctcaatcccgca
gcgcgccaggtgctgaactcggtgttcctgcacgagtgcacggaagccggcctcgacacg
gcgatcgtgcacgcgtcgaagatcctgccgatggcgcgcatccccgacgagcagcgcgag
accgcgctcgacctggtctacgaccgtcgccgcgaggggtacgacccgctgcagaagctc
atggagttgttcgagggcgtctcggcggcctccgcgcgcgagtcacgggccgaggagttg
gcggcgctgccgctgttcgagcggctcgagcggcgcatcgtcgacggcgagcggaacggg
ctcgaggccgacctcgatgccgcgatggtcgagcgtccgccgctcgagatcatcaacgag
accctgctctcgggcatgaagaccgtcggcgagctcttcggctccggccagatgcagttg
ccgttcgtgttgcagtcggccgaggtcatgaaggccgcggtcgcgtacctcgagccgcac
atggagtcgaccggcgacgagggcaagggccggatcgtgctcgccaccgtcaagggcgac
gtgcacgacatcggtaagaacctcgtcgacatcatcctgtccaacaacgggtacgaggtc
gtcaacatcggcatcaagcagccgatcgcgaccatcctcgacgtcgctctcgacaagaag
gccgacgtcatcggcatgtcgggtctgctcgtgaaatcgacggtcgtgatgaaggagaac
ctcgaggaactcaacgcgaagggtgtcgcggagcagttcccggtcctgctcggcggtgcg
gcgctcactcgctcgtacgtcgagaacgatctgtccgacgtctaccagggcgaggtttcc
tacgcgcgggacgcgttcgagggcctgcatctgatggacacgatcatggccgtcaagcgc
ggcgagggtccggcaccggacagcccggaggcgatcgcggccgcagagaaggcggccgag
cgcaaggccaggcatgagcgctccaagcggatcgcggagaagcgcaaggcagagtctgcg
cccgtcgaggttccggagcggtccgacgtcgccgccgacatcgtcgtgccgactccgccg
ttctggggtacccgcatcgtgaagggcatcgcactggccgagtattcgggtctactcgac
gagcgtgcgttgttcctggggcagtggggtctgcgcggtcagcgggccggcgacggcccg
acgtacgaggaactggtcgagaccgaggggcgtccgcgcctgcggtactggctggaccgg
ctgagcacggagggtgtgctccagcatgccgccgtcgtctacggatacttcccggccgtc
tccgagggcgacgacgtgatcgtcctcgagtcaccggaccccgatgcgcccgagcggttt
cggttcacgttcccgcgtcagcagcgcgatcggttcctgtgcatcgcggacttcgtgcgc
tcccgtgacgacgcccgcaaggacgggcaggtcgacgtgctgcccatgaacctcgtgacg
atgggccagcccatcgcggacttcgcgaacgagttgttcgccgcgaattcctaccgcgac
tacctcgaggtgcacggcatcggcgtccagctcaccgaggcgctggccgagtactggcac
cgccgggtccgcgaggaactggtgctgcccggcggtcacaacctcgccgagcaggacccc
tcggatgtcgaggacttcttcaagctcgaataccggggcgcgcgttattccttcggctac
ggcgcctgcccggacctcgaggatcggcgcaagctcgtcgcgctgctcgagccggagcgg
atcggcgtcgagctgtcggaggaggtccagctgcatcccgagcagtcgaccgacgcattc
gtcctgcatcacccggaggccaagtacttcaatgtttga
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