KEGG   Prescottella equi: REQ_23110
Entry
REQ_23110         CDS       T01352                                 
Symbol
metH
Name
(GenBank) methionine synthase MetH
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
req  Prescottella equi
Pathway
req00270  Cysteine and methionine metabolism
req00450  Selenocompound metabolism
req00670  One carbon pool by folate
req01100  Metabolic pathways
req01110  Biosynthesis of secondary metabolites
req01230  Biosynthesis of amino acids
req04980  Cobalamin transport and metabolism
req04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:req00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    REQ_23110 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    REQ_23110 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    REQ_23110 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    REQ_23110 (metH)
   04980 Cobalamin transport and metabolism
    REQ_23110 (metH)
Enzymes [BR:req01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     REQ_23110 (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding B12-binding_2 CdhD Senescence_reg
Other DBs
NCBI-ProteinID: CBH48357
UniProt: A0A3S5Y743
LinkDB
Position
2436376..2439954
AA seq 1192 aa
MDGMSAPFHSALLDALKQRVVIGDGAMGTMLQAADLTLDDFLGLEGCNEILNETRPDVLR
DIHRAYFEAGADAVETNTFGCNLPNLADYDIAHRIRDLSERGTRIAREVADEMGPGRDGM
GRFVLGSMGPGTKLPTLGHAPFAVLRDAYTESALGMIEGGADAILVETCQDLLQVKAAII
GSQHAMEKLGRRLPIITHVTVETTGTMLLGSEIGAALTALEPLGIDMIGLNCATGPDEMS
EHLRHLSRHSKLPVSVMPNAGLPQLGPNGAEYPLSAEELAVALSGFVSEFGLSFVGGCCG
TTPEHIRQVADAVRRVEQAKRTPEPEDGTSSLYQAVPFDQDASILMIGERTNSNGSKAFR
EAMIAEDYQKCIDIAKDQTRDGAHMLDLNVDYVGRDGAADMAALASRFATASTLPIMLDS
TEPEVLRAGLEHLGGRCAVNSVNYEDGDGPNSRYQRIMKLVKEHGAAVVALTIDEEGQAR
TAEHKVRIAERLIQDITTTWGLSQSDIIIDALTFPISTGQEEVRRDGIETIEAIREIKRR
YPDVHFTLGISNISFGLNPAARQVLNSVFLHECTEAGLDTAIVHASKILPMARIPDEQRE
TALDLVYDRRREGYDPLQKLMELFEGVSAASARESRAEELAALPLFERLERRIVDGERNG
LEADLDAAMVERPPLEIINETLLSGMKTVGELFGSGQMQLPFVLQSAEVMKAAVAYLEPH
MESTGDEGKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNIGIKQPIATILDVALDKK
ADVIGMSGLLVKSTVVMKENLEELNAKGVAEQFPVLLGGAALTRSYVENDLSDVYQGEVS
YARDAFEGLHLMDTIMAVKRGEGPAPDSPEAIAAAEKAAERKARHERSKRIAEKRKAESA
PVEVPERSDVAADIVVPTPPFWGTRIVKGIALAEYSGLLDERALFLGQWGLRGQRAGDGP
TYEELVETEGRPRLRYWLDRLSTEGVLQHAAVVYGYFPAVSEGDDVIVLESPDPDAPERF
RFTFPRQQRDRFLCIADFVRSRDDARKDGQVDVLPMNLVTMGQPIADFANELFAANSYRD
YLEVHGIGVQLTEALAEYWHRRVREELVLPGGHNLAEQDPSDVEDFFKLEYRGARYSFGY
GACPDLEDRRKLVALLEPERIGVELSEEVQLHPEQSTDAFVLHHPEAKYFNV
NT seq 3579 nt   +upstreamnt  +downstreamnt
gtggacggcatgtctgcaccattccactctgccctgctcgatgcgctgaagcagcgcgtt
gtcatcggcgacggcgccatgggcacgatgttgcaggccgcggatctgactctcgacgac
ttcctcgggctcgaaggctgcaacgagattctcaacgagacccgtcccgacgtgctgcgc
gacatccaccgcgcgtacttcgaggccggcgccgacgcggtcgaaaccaacactttcggt
tgcaacctcccgaacctcgccgactacgacatcgcccaccgcatccgggacctgtccgag
cgcggtacccggatcgcccgcgaggtcgcggacgagatgggtcccggccgcgacggcatg
ggccggttcgtgctcggctcgatgggtccgggcaccaagctgcccaccctcggccacgcc
ccgttcgcggtcctgcgtgacgcctacaccgagtctgcgctcggcatgatcgaggggggc
gccgacgcgatcctcgtcgagacctgccaggacctgctccaggtgaaggctgcgatcatc
ggcagccagcacgcgatggagaagctggggcgccgcctgccgatcatcacccacgtcacg
gtcgagacgaccggcacgatgctgctcggcagcgagatcggcgccgcgctcacggcgctc
gagccgctcggcatcgacatgatcggcctcaactgcgccaccggcccggacgagatgagc
gagcacctgcggcacctgtcgcggcactcgaagctgccggtgtccgtgatgccgaacgcc
ggtctgccgcagctgggtccgaacggggccgagtacccgctgtcggccgaggaactcgcg
gtcgcgctgtcgggcttcgtgagcgagttcggtctgtcgttcgtcggtggctgctgcggc
accacccccgagcacatccgtcaggtcgccgacgccgtccgccgggtcgagcaggcgaag
cgcacgccggagcccgaggacgggacgtcgtcgctgtaccaggcggtgccgttcgatcag
gacgcctcgatcctgatgatcggtgagcggacgaactccaacggctccaaggcgttccgc
gaggccatgatcgccgaggactaccagaagtgcatcgacatcgcgaaggaccagacccgc
gacggcgcgcacatgctcgacctcaacgtcgactacgtcggtcgtgacggcgccgccgac
atggctgcgctcgcaagccgattcgcgaccgcgtcgacgctgccgatcatgctcgactcc
accgagcccgaggtgctccgcgccgggctcgagcatctcggcggccgctgcgccgtcaac
tcggtgaactacgaggacggcgacggcccgaactcgcgctaccagcgaatcatgaagctg
gtcaaggaacacggcgcagcggtcgtggcgctcacgatcgacgaggagggccaggcccgc
accgccgagcacaaggtccggatcgccgagcggttgatccaggacatcaccaccacgtgg
ggcctgtcgcagtcggacatcatcatcgacgcgttgacgttcccgatctcgacggggcag
gaggaggtccgccgcgacggcatcgagaccatcgaggcgatccgcgagatcaaacgccgc
tacccggacgtgcacttcacgctcggtatctcgaacatctcgttcggcctcaatcccgca
gcgcgccaggtgctgaactcggtgttcctgcacgagtgcacggaagccggcctcgacacg
gcgatcgtgcacgcgtcgaagatcctgccgatggcgcgcatccccgacgagcagcgcgag
accgcgctcgacctggtctacgaccgtcgccgcgaggggtacgacccgctgcagaagctc
atggagttgttcgagggcgtctcggcggcctccgcgcgcgagtcacgggccgaggagttg
gcggcgctgccgctgttcgagcggctcgagcggcgcatcgtcgacggcgagcggaacggg
ctcgaggccgacctcgatgccgcgatggtcgagcgtccgccgctcgagatcatcaacgag
accctgctctcgggcatgaagaccgtcggcgagctcttcggctccggccagatgcagttg
ccgttcgtgttgcagtcggccgaggtcatgaaggccgcggtcgcgtacctcgagccgcac
atggagtcgaccggcgacgagggcaagggccggatcgtgctcgccaccgtcaagggcgac
gtgcacgacatcggtaagaacctcgtcgacatcatcctgtccaacaacgggtacgaggtc
gtcaacatcggcatcaagcagccgatcgcgaccatcctcgacgtcgctctcgacaagaag
gccgacgtcatcggcatgtcgggtctgctcgtgaaatcgacggtcgtgatgaaggagaac
ctcgaggaactcaacgcgaagggtgtcgcggagcagttcccggtcctgctcggcggtgcg
gcgctcactcgctcgtacgtcgagaacgatctgtccgacgtctaccagggcgaggtttcc
tacgcgcgggacgcgttcgagggcctgcatctgatggacacgatcatggccgtcaagcgc
ggcgagggtccggcaccggacagcccggaggcgatcgcggccgcagagaaggcggccgag
cgcaaggccaggcatgagcgctccaagcggatcgcggagaagcgcaaggcagagtctgcg
cccgtcgaggttccggagcggtccgacgtcgccgccgacatcgtcgtgccgactccgccg
ttctggggtacccgcatcgtgaagggcatcgcactggccgagtattcgggtctactcgac
gagcgtgcgttgttcctggggcagtggggtctgcgcggtcagcgggccggcgacggcccg
acgtacgaggaactggtcgagaccgaggggcgtccgcgcctgcggtactggctggaccgg
ctgagcacggagggtgtgctccagcatgccgccgtcgtctacggatacttcccggccgtc
tccgagggcgacgacgtgatcgtcctcgagtcaccggaccccgatgcgcccgagcggttt
cggttcacgttcccgcgtcagcagcgcgatcggttcctgtgcatcgcggacttcgtgcgc
tcccgtgacgacgcccgcaaggacgggcaggtcgacgtgctgcccatgaacctcgtgacg
atgggccagcccatcgcggacttcgcgaacgagttgttcgccgcgaattcctaccgcgac
tacctcgaggtgcacggcatcggcgtccagctcaccgaggcgctggccgagtactggcac
cgccgggtccgcgaggaactggtgctgcccggcggtcacaacctcgccgagcaggacccc
tcggatgtcgaggacttcttcaagctcgaataccggggcgcgcgttattccttcggctac
ggcgcctgcccggacctcgaggatcggcgcaagctcgtcgcgctgctcgagccggagcgg
atcggcgtcgagctgtcggaggaggtccagctgcatcccgagcagtcgaccgacgcattc
gtcctgcatcacccggaggccaagtacttcaatgtttga

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