KEGG   Roseburia faecis: ACIRUI_04390
Entry
ACIRUI_04390      CDS       T10789                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
rfc  Roseburia faecis
Pathway
rfc03030  DNA replication
rfc03410  Base excision repair
rfc03420  Nucleotide excision repair
rfc03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:rfc00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    ACIRUI_04390 (ligA)
   03410 Base excision repair
    ACIRUI_04390 (ligA)
   03420 Nucleotide excision repair
    ACIRUI_04390 (ligA)
   03430 Mismatch repair
    ACIRUI_04390 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:rfc03032]
    ACIRUI_04390 (ligA)
   03400 DNA repair and recombination proteins [BR:rfc03400]
    ACIRUI_04390 (ligA)
Enzymes [BR:rfc01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     ACIRUI_04390 (ligA)
DNA replication proteins [BR:rfc03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     ACIRUI_04390 (ligA)
DNA repair and recombination proteins [BR:rfc03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     ACIRUI_04390 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     ACIRUI_04390 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     ACIRUI_04390 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      ACIRUI_04390 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB BRCT PTCB-BRCT Nlig-Ia HHH_2 BRCT_2 Lar_restr_allev RUBY_RBDX DNA_ligase_ZBD
Other DBs
NCBI-ProteinID: XKQ66183
LinkDB
Position
complement(873273..875243)
AA seq 656 aa
METEKQRIEELVKQLNAASAAYYNGQDEIMPNYEWDALFDELTTLEEKTGYIIKDSPTQN
AGYEESGSGQKEPHEYPALSLAKTKQVEELQQWAGAYPIWLSWKLDGLTLVLTYDNGNLV
KILTRGNGNLGTNITFLKGAIGGFPQKISYQGHLVVRGEAAISYTDFAQINDMIEDDDEK
YANPRNLASGTLNLEDPAEVKARHVRFHAFTLVHLDEPMVSWGERMHFLEKLGFDVVDRE
ATTAQKLPEAIDRWTKLVESGKMDIPVDGLVICYDDTDYAASGSVTGHHATRAGFAFKWQ
DEAVDTKLKYIEWSCAVSTISPVAVFEPVQIEGTTVSRASLCNISEIERLGIGKECTLSV
IKANKIIPKCIAVKDAVGAPEIPSQCPVCHAPTKVHVSENSGTKTLHCTNPDCTAKNVKK
FTRFVSKWGMDIDGLSIQTMLRFMNAGFIHEFADIFRLKEHFGEISQMEGFGEKSVANME
QSIEKSRQVHPVNFIFALCIPLIGVDAGKKIVAAIGFEGFLQRLHQGDGFEDIEGIGAER
SRSIVTWYQNEKNHSGFEDLLHELSIEHVEVQDTSSGSCAGLSFVITGDVHHYKNRDEFK
AYVESQGGKVTGSVSKKTAYLVNNDVESASSKNRKAKELGIPIISEDTFIEQFGGR
NT seq 1971 nt   +upstreamnt  +downstreamnt
atggaaacagaaaagcaacggattgaagaactggtaaaacagttgaatgcagcatcagct
gcgtattataacggacaggatgaaatcatgccaaattatgagtgggatgctttgtttgat
gagcttaccacgctggaagaaaaaaccggatatattataaaggacagcccgacgcagaat
gccggatatgaagaatccggaagcggacaaaaagaaccgcatgagtatccggcactttct
ctggcgaagaccaaacaggtggaagaactgcagcaatgggcgggagcttatccgatctgg
ctgtcatggaaactggacggacttacgctggttctgacgtatgataacggaaatcttgta
aaaattcttaccagaggaaatggaaacctgggtaccaacattacatttttaaagggtgcg
atcggaggattcccgcaaaagatttcgtatcaggggcatctggttgtgcgaggagaagct
gccatatcctatacagattttgcacagatcaacgacatgattgaggatgacgatgaaaaa
tatgcaaatccgcgaaatctggcatccggaacgctgaatctggaagatccggcagaagtg
aaggcacgccatgtcaggtttcatgcatttacactggtgcatctggatgagccgatggta
tcgtggggagagcggatgcactttctggaaaaactgggatttgatgtggtagacagggaa
gcgacaaccgcccaaaaacttccggaagccattgaccgatggacgaaacttgtagagagc
ggaaaaatggatattccggtagatggtctggtgatctgttatgatgatacggattatgcg
gcatcgggaagcgtgaccgggcatcatgcgacacgtgccggttttgcgttcaaatggcag
gatgaggctgtagatacaaaactaaagtatatcgaatggtcgtgtgcggtatcaacaatt
tccccagttgccgtgtttgaaccggtacagattgagggaacgacagtatccagggcatcg
ctatgtaatatcagtgagatcgagcgtctggggattggaaaagagtgcacactttctgtg
atcaaagctaataagatcattccgaaatgtattgcggtaaaagatgctgtaggtgctccg
gagattccatcccagtgtccggtgtgccatgcaccgacaaaagttcatgtgagtgaaaac
agtggcacaaagaccctgcattgtaccaatccggactgtacagccaaaaatgtcaagaaa
tttacccgttttgtcagcaagtgggggatggatattgacggtctttccattcagacgatg
ctccgttttatgaatgcgggatttatccatgaatttgcggatattttccgtttgaaagag
catttcggggagatcagccagatggagggctttggtgaaaaatctgtggcaaatatggaa
cagtccattgaaaaaagccggcaggtacatccggtgaactttatatttgccctgtgcata
ccgctgatcggtgtggatgccgggaaaaaaattgttgccgccattggttttgaaggcttt
ttgcaacgtctgcatcagggggacgggtttgaggatattgaggggatcggagcggaacgt
tcccgatcaattgtaacctggtatcagaatgaaaaaaaccacagtgggtttgaggatctg
cttcatgaactttcgatagaacatgtagaagtgcaggatacttcttccggaagctgtgcg
ggactgagttttgtgatcaccggagatgtgcatcactataaaaacagggatgaatttaag
gcctatgtagaaagccagggcggaaaagtgacaggaagtgtctcaaaaaagacggcatat
cttgtcaacaatgacgtggaatccgcatcatctaagaatcgtaaggcaaaagaactggga
attccgattatttccgaagatacatttatagaacaatttggtgggaggtag

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