KEGG   Rhinolophus ferrumequinum (greater horseshoe bat): 117012414
Entry
117012414         CDS       T07722                                 
Symbol
IL6
Name
(RefSeq) interleukin-6
  KO
K05405  interleukin 6
Organism
rfq  Rhinolophus ferrumequinum (greater horseshoe bat)
Pathway
rfq01521  EGFR tyrosine kinase inhibitor resistance
rfq01523  Antifolate resistance
rfq04060  Cytokine-cytokine receptor interaction
rfq04061  Viral protein interaction with cytokine and cytokine receptor
rfq04066  HIF-1 signaling pathway
rfq04068  FoxO signaling pathway
rfq04151  PI3K-Akt signaling pathway
rfq04218  Cellular senescence
rfq04620  Toll-like receptor signaling pathway
rfq04621  NOD-like receptor signaling pathway
rfq04623  Cytosolic DNA-sensing pathway
rfq04625  C-type lectin receptor signaling pathway
rfq04630  JAK-STAT signaling pathway
rfq04640  Hematopoietic cell lineage
rfq04657  IL-17 signaling pathway
rfq04659  Th17 cell differentiation
rfq04668  TNF signaling pathway
rfq04672  Intestinal immune network for IgA production
rfq04931  Insulin resistance
rfq04932  Non-alcoholic fatty liver disease
rfq04933  AGE-RAGE signaling pathway in diabetic complications
rfq04936  Alcoholic liver disease
rfq05010  Alzheimer disease
rfq05020  Prion disease
rfq05022  Pathways of neurodegeneration - multiple diseases
rfq05132  Salmonella infection
rfq05133  Pertussis
rfq05134  Legionellosis
rfq05135  Yersinia infection
rfq05142  Chagas disease
rfq05143  African trypanosomiasis
rfq05144  Malaria
rfq05146  Amoebiasis
rfq05152  Tuberculosis
rfq05161  Hepatitis B
rfq05162  Measles
rfq05163  Human cytomegalovirus infection
rfq05164  Influenza A
rfq05166  Human T-cell leukemia virus 1 infection
rfq05167  Kaposi sarcoma-associated herpesvirus infection
rfq05168  Herpes simplex virus 1 infection
rfq05169  Epstein-Barr virus infection
rfq05171  Coronavirus disease - COVID-19
rfq05200  Pathways in cancer
rfq05202  Transcriptional misregulation in cancer
rfq05321  Inflammatory bowel disease
rfq05323  Rheumatoid arthritis
rfq05332  Graft-versus-host disease
rfq05410  Hypertrophic cardiomyopathy
rfq05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rfq00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    117012414 (IL6)
   04668 TNF signaling pathway
    117012414 (IL6)
   04066 HIF-1 signaling pathway
    117012414 (IL6)
   04068 FoxO signaling pathway
    117012414 (IL6)
   04151 PI3K-Akt signaling pathway
    117012414 (IL6)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    117012414 (IL6)
   04061 Viral protein interaction with cytokine and cytokine receptor
    117012414 (IL6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    117012414 (IL6)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    117012414 (IL6)
   04620 Toll-like receptor signaling pathway
    117012414 (IL6)
   04621 NOD-like receptor signaling pathway
    117012414 (IL6)
   04623 Cytosolic DNA-sensing pathway
    117012414 (IL6)
   04625 C-type lectin receptor signaling pathway
    117012414 (IL6)
   04659 Th17 cell differentiation
    117012414 (IL6)
   04657 IL-17 signaling pathway
    117012414 (IL6)
   04672 Intestinal immune network for IgA production
    117012414 (IL6)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    117012414 (IL6)
   05202 Transcriptional misregulation in cancer
    117012414 (IL6)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    117012414 (IL6)
   05161 Hepatitis B
    117012414 (IL6)
   05171 Coronavirus disease - COVID-19
    117012414 (IL6)
   05164 Influenza A
    117012414 (IL6)
   05162 Measles
    117012414 (IL6)
   05168 Herpes simplex virus 1 infection
    117012414 (IL6)
   05163 Human cytomegalovirus infection
    117012414 (IL6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    117012414 (IL6)
   05169 Epstein-Barr virus infection
    117012414 (IL6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    117012414 (IL6)
   05135 Yersinia infection
    117012414 (IL6)
   05133 Pertussis
    117012414 (IL6)
   05134 Legionellosis
    117012414 (IL6)
   05152 Tuberculosis
    117012414 (IL6)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    117012414 (IL6)
   05144 Malaria
    117012414 (IL6)
   05142 Chagas disease
    117012414 (IL6)
   05143 African trypanosomiasis
    117012414 (IL6)
  09163 Immune disease
   05323 Rheumatoid arthritis
    117012414 (IL6)
   05321 Inflammatory bowel disease
    117012414 (IL6)
   05332 Graft-versus-host disease
    117012414 (IL6)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    117012414 (IL6)
   05020 Prion disease
    117012414 (IL6)
   05022 Pathways of neurodegeneration - multiple diseases
    117012414 (IL6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    117012414 (IL6)
   05410 Hypertrophic cardiomyopathy
    117012414 (IL6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    117012414 (IL6)
   04932 Non-alcoholic fatty liver disease
    117012414 (IL6)
   04931 Insulin resistance
    117012414 (IL6)
   04933 AGE-RAGE signaling pathway in diabetic complications
    117012414 (IL6)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    117012414 (IL6)
   01523 Antifolate resistance
    117012414 (IL6)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:rfq04052]
    117012414 (IL6)
Cytokines and neuropeptides [BR:rfq04052]
 Cytokines
  Interleukins
   117012414 (IL6)
SSDB
Motif
Pfam: IL6 GCSF IL23 DUSP
Other DBs
NCBI-GeneID: 117012414
NCBI-ProteinID: XP_032944564
Ensembl: ENSRFEG00010009963
UniProt: A0A671EWV4
LinkDB
Position
20:complement(17685762..17690138)
AA seq 209 aa
MNSLSTSTFSPVAFSLGLLLVTATAFPTPVPRGEDSKDDTTSNRPPLTSTNQSENLIKSI
FYEISEVREKMCGNDDTCKNSREALTEDNLNLPKMSEKDGCFQSGFNQETCLMRITTGLL
EFQIYLEYLQNKFEENAKAMQMRTKALVLILKQRVKNPDEVTTPDPITNSSLLAKMRSQS
EWLENTTTHLILRSLEDFLQFTQRAVRIM
NT seq 630 nt   +upstreamnt  +downstreamnt
atgaactccctctccacaagcaccttcagtccagttgccttctccctggggctactcctg
gtgacggctactgctttccctacgccagttccccggggagaagattccaaagatgacacc
acctcaaacagaccaccactcacctctacaaaccaaagtgaaaacctcattaagtccatc
ttctacgaaatctctgaagtgagagagaagatgtgtggcaacgatgacacatgtaaaaac
agcagggaggcactgacagaagacaacctgaaccttccaaaaatgtcagaaaaagatgga
tgcttccagtctgggttcaatcaggagacttgcctgatgagaatcaccaccggtcttctg
gagtttcagatatacctggagtacctccagaacaagtttgaggagaacgccaaggcaatg
cagatgagaaccaaagccctggtcctgatcctgaagcaaagggtaaagaatccagatgaa
gtaaccacccctgacccaatcacaaactccagcctgctggctaagatgcggtcgcagagc
gagtggctggaaaacaccacaactcacctcatcctgcgaagccttgaggatttcctgcag
ttcacccagagggctgtgcgcataatgtag

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