Rhinolophus ferrumequinum (greater horseshoe bat): 117021767
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Entry
117021767 CDS
T07722
Symbol
IRS2
Name
(RefSeq) insulin receptor substrate 2 isoform X1
KO
K07187
insulin receptor substrate 2
Organism
rfq
Rhinolophus ferrumequinum (greater horseshoe bat)
Pathway
rfq04022
cGMP-PKG signaling pathway
rfq04068
FoxO signaling pathway
rfq04081
Hormone signaling
rfq04140
Autophagy - animal
rfq04152
AMPK signaling pathway
rfq04211
Longevity regulating pathway
rfq04213
Longevity regulating pathway - multiple species
rfq04910
Insulin signaling pathway
rfq04920
Adipocytokine signaling pathway
rfq04923
Regulation of lipolysis in adipocytes
rfq04930
Type II diabetes mellitus
rfq04931
Insulin resistance
rfq04932
Non-alcoholic fatty liver disease
rfq04935
Growth hormone synthesis, secretion and action
rfq05010
Alzheimer disease
rfq05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
rfq00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
117021767 (IRS2)
04022 cGMP-PKG signaling pathway
117021767 (IRS2)
04152 AMPK signaling pathway
117021767 (IRS2)
09133 Signaling molecules and interaction
04081 Hormone signaling
117021767 (IRS2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
117021767 (IRS2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
117021767 (IRS2)
04923 Regulation of lipolysis in adipocytes
117021767 (IRS2)
04920 Adipocytokine signaling pathway
117021767 (IRS2)
04935 Growth hormone synthesis, secretion and action
117021767 (IRS2)
09149 Aging
04211 Longevity regulating pathway
117021767 (IRS2)
04213 Longevity regulating pathway - multiple species
117021767 (IRS2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
117021767 (IRS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
117021767 (IRS2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
117021767 (IRS2)
04932 Non-alcoholic fatty liver disease
117021767 (IRS2)
04931 Insulin resistance
117021767 (IRS2)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
IRS
PH
PH_11
MEKK4_N
Mcp5_PH
Motif
Other DBs
NCBI-GeneID:
117021767
NCBI-ProteinID:
XP_032960996
Ensembl:
ENSRFEG00010007964
UniProt:
A0A671EJ09
LinkDB
All DBs
Position
4:complement(53101906..53130439)
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AA seq
1407 aa
AA seq
DB search
MASPPLHVPPGPAGGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGAGGDEA
TATAGGGPAPLPPRLEYYESEKKWRSKASAPKRVISLDCCLNINKRADAKHKYLIALYTK
DEYFAVAAENEQEQEGWYRALTDLVSEGRAGAGDAPPTAASAGSCSALPGALGGSAGADD
SYGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQL
MNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFRP
RSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRVR
TASEGDGGAAAGTGAVGGRPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRASKVTLAPAG
GALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPHLQHPLHHHAGQRPS
SGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPAREGSGSELYGYM
TMDRPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRA
TFSSSSGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGTDDGYMPMTPGAALM
GGGSGSCKSDDYMPMSPTSVSAPKQILQPRAATVALPPTGAAVPAPASAASRAFPVNGAS
YKASSPAESSPEDSGYMRMWCGSKLSMENTDSKLLPNGDYLNMSPSDAGASGTPPDFFSA
ALHGGGEMLRGVPGYCYSSLPRSYKAPYTCNGDNDQYVLMSSPVGRILEEERLEPQASSG
TTPSASVFVAGVGGGGHTQPPHSVVPSPGRLSGSGGGRPEGFLNQRCRAVRPTRLSLEGL
QTLPRMHEYPLPPEPKSPGEYINIDFGEAGAHLSPPAPPLLTSAASSSSLLSASSPASSL
GSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGLQSGDPVGSLDALLSPEASSRYPPLP
PRPAAPSSSLQPQLPPPPPPGELYRLPAASTSQGPSAASSSSSETGDNGDYTEMAFGVAA
TPPQPIVAPPKPEGARVTSPTSGVKRLSLMDQVSGVEAFLQAGQPPDPHRGAKVIRADPQ
GGRRRHSSETFSSTTTVTPVSPSFAHNSKRHNSASVENVSLRKSSEGGGSGVLSGGDEPP
TSPRQLQPPPPQQGRPWTPSQPGGLVGCPGGSGSPMRRETSAGFQNGLNYIAIDVRDEPG
LSPPPQQHPHPQQHPHPQPGDKSAWGRTRSLGGLISAVGANSTSGVCGGSGPGALPSTNT
YASIDFLSHHLKEATIVKDIHDLSRKTPFSSCAEEASWPPSAPSTLNASCSENLPLLDPL
PSATVATVVRGGQPHLAGQLWVTNPSG
NT seq
4224 nt
NT seq
+upstream
nt +downstream
nt
atggcgagcccgccgctgcatgtcccccctgggccggcgggcggcgacggccccaacctc
aacaacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcag
aagcacggacacaagcgcttcttcgtgctgcgcggccccggcgcgggcggcgacgaggca
acggcgacagcgggcgggggtccggcgccgctgccgccgcggctcgagtactacgaaagc
gagaagaagtggcggagcaaggcgagcgccccgaagcgggtcatctcgctcgactgctgc
ctgaacatcaacaagcgcgccgacgccaagcacaagtacctgatcgccctttacaccaag
gacgagtacttcgccgtggccgccgagaacgagcaggaacaggagggctggtaccgcgcg
ctcaccgacctggtcagcgagggccgcgcgggtgccggcgacgcgccccccactgccgcc
agtgccgggtcctgcagcgccttgcccggagccctgggcggctcagccggcgccgatgac
agctacgggctggtggcacccgccacggctgcctaccgcgaggtatggcaggtgaacctg
aagcccaagggcctgggccagagcaagaacctgacaggcgtgtaccgcctgtgcctgtcg
gcgcgcaccatcggcttcgtgaagctcaactgcgagcagccgtcggtgactctgcagctc
atgaacattcgccgctgcggccactcggacagtttctttttcatcgaggtgggccgctcg
gctgtcacgggacccggcgaactgtggatgcaggccgacgactcggtggtggcacagaac
atccacgagaccatcctggaggccatgaaggcgctcaaggagctcttcgagttccggccg
cgcagcaagagccagtcgtcgggctcgtcggccacgcaccccattagcgtccccggcgcg
cgccgccaccaccacctggttaatctgccccccagccagacgggtctggtgcgccgctcg
cgcaccgacagcctggctgccaccccgccggccgctaagtgcagctcctgccgggtgcgc
acagccagcgagggcgacggcggcgcggcggcagggactggggcggtgggcggcaggcct
gtgtcggtggcgggcagccccctgagtcccgggccggtgcgcgcgcccctgagtcgctcg
cacaccctgagtggcggctgcggcggccgcgcgagcaaggtgactctggcgccggcaggg
ggcgccctgcaacacagccgctccatgtccatgcctgtggcgcactcgcccccggctgcc
accagccccggcagcctgtcgtccagcagcggacacggctctggctcctaccctccgcct
ccgggcccgcacccgcacctgcagcaccccttgcaccatcatgcgggccagcggccctcc
agcggcagcgcctcagcctctggctcccccagtgaccccggtttcatgtccctggatgag
tatggctccagccctggggacttgagagctttttgtagccacaggagcaatacgcctgag
tccatcgccgagacacctccggccagggagggcagcgggagcgaattgtacgggtacatg
accatggacaggcccctgagccactgtggccgtccctaccgtcgagtctcaggggatgga
gctcaggacttggacagagggcttaggaagaggacttactccttgaccacacctgccagg
cagcggccggtgccccagccctcctccgcatccctggatgaatacaccctgatgcgggcc
accttctccagcagctctggccgcctctgcccttcctgccccgcgtcttctcccaaagtg
gcctaccacccctatcccgaggactacggggacattgagattgggtcccacaggagctcc
agcagtaacctgggcacggacgatggctacatgcccatgacccctggtgcagccctcatg
ggtggtggcagtggcagctgcaaaagtgacgactacatgcccatgagccccaccagcgtg
tctgccccaaagcagatcctgcagccacgggctgccactgtggccttgccccccacggga
gctgcagtgccagcgcctgcctctgcggccagcagggcctttccggtgaatggggccagc
tacaaggctagctccccggcggagagctcccccgaggacagtggatacatgcgcatgtgg
tgtggctccaagctgtccatggagaacacagacagcaagctgcttcccaatggggactac
ctcaacatgtcccccagcgacgcgggcgcgtcgggaaccccgccggacttcttctccgca
gccctgcatggcggaggggagatgctcaggggcgtccctggctactgctacagctccttg
cctcgctcctacaaggctccctacacctgcaacggggacaatgaccagtatgtgctcatg
agctcccccgtggggcgcatcctggaagaggagaggctggagccgcaggccagttcgggg
accacgccgtcggccagcgtcttcgtggctggggtgggtggtggtggccacacccagcct
cctcactctgtagtgccttcgcctgggagactgagtggcagcggcggtggccgcccggaa
ggcttcctgaaccagcgctgccgggcagtgcggcccacgcgcctgtccctggaggggctt
cagaccctgcctaggatgcacgagtatcctctgccacctgagcccaagagcccgggcgag
tacatcaacattgactttggcgaggcgggagcacatttgtcgccacctgcccctccgctg
ctgacgtcggcggcctcctcctcctcgctgttgtctgccagcagcccagcctcatccctg
ggctctggtacccctggcacgagcagcgacagccggcagcgctcccctctctccgactac
atgaacctcgacttcagctcgcccaagtcccccaagccgggtctccagagcggggaccca
gtgggctccttggatgccctcctgtcccccgaggcctcctcccggtacccaccgctgccc
ccacgccctgccgccccctcttcctccctgcagccacagctgcctccaccaccaccccca
ggagagctgtaccgcctgcctgcagcatccacgtcccagggccccagcgctgcctcctct
tcgtcctcggagactggggacaatggtgactacaccgagatggcctttggcgtggctgcc
accccgccacaacccatcgtggctcccccgaagccggaaggtgcccgcgtgaccagcccc
acgtctggcgtgaagaggctgagtctcatggatcaggtgtctggggttgaggccttcctg
caggctggccagcccccagacccacaccgaggggccaaggtcatccgcgcagacccgcag
gggggccgccgccgccacagctccgagaccttctcctcgaccaccactgtgacccccgtg
tccccgtccttcgcccacaactcgaagcgccacaactcagcctccgtggaaaatgtctct
ctcaggaaaagcagcgaagggggtggcagtggcgtcctcagtgggggcgacgagcccccc
acatccccccgccagttgcagccaccgcctccccagcaggggcggccatggacaccgagt
cagcctggaggcctggttggctgccccgggggaagtggctctccaatgcgcagggagacc
tctgccggcttccagaatggcctcaactacatcgccatcgacgtgagggatgagccagga
ctgtcgccgcccccacagcagcacccgcatccgcagcagcatccgcatccgcagccaggc
gacaagagcgcctggggccggacccgtagcctcggcggtctcatcagcgctgtgggggcc
aacagcaccagtggggtgtgtggggggtcgggccctggcgccctgccttccaccaacacc
tatgccagcattgacttcttgtcccatcacctgaaggaggccaccattgtgaaagacatc
catgatctatccaggaagacccccttctcctcctgtgcggaggaggcctcctggccacca
tcagccccctccacccttaatgcctcctgctctgaaaacctgccgctgctggaccctctg
ccctctgccacagtggccactgttgtcagaggagggcagccccacttggctgggcagctc
tgggttaccaacccatcaggctga
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