Rhinolophus hipposideros (lesser horseshoe bat): 308487514
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Entry
308487514 CDS
T12007
Symbol
HSD11B1
Name
(RefSeq) 11-beta-hydroxysteroid dehydrogenase 1 isoform 1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
rhii Rhinolophus hipposideros (lesser horseshoe bat)
Pathway
rhii00140
Steroid hormone biosynthesis
rhii00980
Metabolism of xenobiotics by cytochrome P450
rhii01100
Metabolic pathways
rhii05204
Chemical carcinogenesis - DNA adducts
Brite
KEGG Orthology (KO) [BR:
rhii00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
308487514 (HSD11B1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
308487514 (HSD11B1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
308487514 (HSD11B1)
Enzymes [BR:
rhii01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
308487514 (HSD11B1)
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Ortholog
Paralog
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
THF_DHG_CYH_C
DUF1776
Shikimate_DH
Pyr_redox_3
AdoHcyase_NAD
2-Hacid_dh_C
Pyr_redox_2
NmrA
Motif
Other DBs
NCBI-GeneID:
308487514
NCBI-ProteinID:
XP_080881978
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All DBs
Position
19:34803477..34848385
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AA seq
291 aa
AA seq
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MAFMKNSLLPILGLFLAYYYSTYEEFTPEMLRGKKVIVTGASKGIGKEMAYHLAKMGAHV
MVTARSEETLKKVVSHCQELGAASAHYIAGSMDDMTFAEQFVAKAGKLMGGLDMLILNHI
TSATMVPFNGDVHLVRKSMEVNFLSYVVLSMAALPMLKQSNGSIVVVSSVAGKIASPLVA
PYAASKFALDGFFSSIRMEYSVTKVNVSITLCILGLINTDTAIKAVSGILDTEASPKEEC
ALEIIKGGALRQEEVYYVNSVWTALLLKTPVRKILEFLSLRNYNMDKFIKN
NT seq
876 nt
NT seq
+upstream
nt +downstream
nt
atggcttttatgaaaaactctctgctccccattctggggctcttcttggcctactactat
tctacatatgaggaattcacaccagagatgctccgaggaaagaaagtgattgtcacaggg
gccagcaaggggatcggaaaagagatggcctatcatctggcgaagatgggagcccatgtg
atggtgacagcgaggtcagaagaaactctaaagaaggtggtgtcccactgccaggagctt
ggcgcagcctcggcacactacattgctggcagcatggacgacatgacttttgcagagcaa
tttgttgccaaagctggaaagctcatgggaggactagacatgctcattctcaaccacatc
accagcgctactatggtaccattcaatggtgatgtccacttagtgcgcaaaagcatggag
gtgaacttcctgagttacgtggtcctgagtatggctgccttgcccatgctgaagcagagc
aacggaagcattgttgtcgtctcctccgtggctgggaaaatagctagtccacttgttgct
ccctatgctgcaagcaaatttgccctggatgggtttttctcctccatcagaatggaatat
tcagtgaccaaagtcaatgtgtcgattactctctgtatcctcggactcataaacacagac
acagccataaaggcagtttctgggatacttgacacagaagcatctccaaaggaagaatgt
gccctggagattatcaaagggggagctctgcgtcaagaggaagtgtattatgtcaattca
gtatggactgctctcctactgaaaactccagtgagaaagatcctagaatttctctcccta
agaaattataatatggacaaatttataaaaaattag
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