Rhodococcus sp. p52: IM25_20225
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Entry
IM25_20225 CDS
T05434
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
rhq
Rhodococcus sp. p52
Pathway
rhq00010
Glycolysis / Gluconeogenesis
rhq00020
Citrate cycle (TCA cycle)
rhq00620
Pyruvate metabolism
rhq00785
Lipoic acid metabolism
rhq01100
Metabolic pathways
rhq01110
Biosynthesis of secondary metabolites
rhq01120
Microbial metabolism in diverse environments
rhq01200
Carbon metabolism
rhq01210
2-Oxocarboxylic acid metabolism
Module
rhq_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
rhq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
IM25_20225
00020 Citrate cycle (TCA cycle)
IM25_20225
00620 Pyruvate metabolism
IM25_20225
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
IM25_20225
Enzymes [BR:
rhq01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
IM25_20225
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AOD23615
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Position
4382321..4385170
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AA seq
949 aa
AA seq
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MTDLIHGSDSREGAAPGASGPDSSAKPASTKDNRVRVIREGVASYLPDIDPAETEEWLES
FDGMLEAAGPTRARYLLLRMLERANERKVSLPALTSTDYVNTIPTESEPWFPGDEEVERR
FRAYIRWNAAIMVTRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKDHPGGGDQVFIQ
GHASPGIYARAFLEGRIGTEQLDGFRQEHSHASLGGGLPSYPHPRLLPTFWEFPTVSMGL
GPMNAIYQARFNHYLHDRGIKDTSDQHVWAFLGDGEMDEPESRGLAHVAATEGLDNLTFV
VNCNLQRLDGPVRGNGKIIQELESFFRGSGWNVIKVVWGREWDALLHADKDGALVNLMNA
TPDGDYQTYKANDGAFVREHFFGRDPRTKELVKDLSDQQIWNLKRGGHDYRKIYAAYKAA
MEHKGQPTVILAHTIKGYTLGKHFEGRNATHQMKKLTLEDLKYFRDIQRIPISDEELEKD
PKMPPYYHPGFESPEIQYMLERRRALGGFLPERRTTAKPLALPAEKTYDVVRKGSGKQEV
ATTMATVRVLKELLRDKEIGKRIVPIIPDEARTFGMDSWFPSLKIYNRNGQLYTSVDADL
MLAYKESEVGQILHEGINEAGSTASFTAVGTSYATQGEPMIPVYIFYSMFGFQRTGDGLW
AAADQMARGFALGATAGRTTLTGEGLQHADGHSLLLASTNPAAVTYDPAFSYEIAHIFRD
GLRRMYGGTEGVDGFGGEDVFYYITIYNEPYSQPAEPEDLDVEGLLKGIYLYKRGPESGP
KAQILVSGVMMPEALRAQKMLADEWGVSADVWSVTSWGELRRDGVECDRQALLNPGEEAS
VPYVASVLNDAAGPFVAVSDWMRAVPDQIRKWVPGDYTVLGADGFGFSDTRGAARRVFNI
DAESTVVAVLSALGREGAIDREKAVEAARTYKIDDVTAAPVSMADPGVA
NT seq
2850 nt
NT seq
+upstream
nt +downstream
nt
ttgacagacctgatccacggatccgactcccgagaaggcgccgcaccgggcgcgtcggga
ccggattcctcggccaagccggcatcgaccaaggacaaccgtgtccgggtgatccgcgag
ggtgtggcctcctatctgccggacatcgatccggcggagaccgaagagtggctcgagtcg
ttcgacgggatgctcgaggccgcgggccccacccgcgcgcgctacctgctgctgcgcatg
ctcgagcgtgccaacgagcgcaaggtctcccttcccgccctgacctccaccgactacgtc
aacaccatccccaccgagagcgaaccgtggttccccggtgacgaggaggtcgagcgtcgc
ttccgcgcgtacatccggtggaacgcggcgatcatggtcacccgcgcgcagcgcccgggt
gtcggcgtcggtggtcacatctccacctacgcgtcgtccgccgccctgtacgaggtcggc
ttcaaccacttcttccgcggcaaggaccatcccggcggcggcgaccaggtcttcatccag
ggccacgcctcccccggtatctacgcccgagccttcctcgagggccgcatcggcacggag
cagctcgacggcttccgtcaggagcacagccacgcctcgctcggcggcggcctgccctcg
tacccgcacccgcgcctgctcccgaccttctgggagttcccgaccgtgtccatgggcctg
ggcccgatgaacgcgatctaccaggcacggttcaatcactacctgcacgaccggggcatc
aaggacacctccgatcagcacgtctgggcgttcctcggcgacggcgagatggacgagccg
gagtcgcgcggtctggcgcacgtcgcggccaccgagggtctcgacaacctgaccttcgtc
gtcaactgcaacctgcagcgtctcgacggcccggtgcgcggcaacggcaagatcatccag
gagctggagtcgttcttccgcggctccggctggaacgtcatcaaggtcgtgtggggccgc
gagtgggacgccctgctgcacgccgacaaggacggcgcactggtcaatctcatgaacgcc
acccccgacggcgactaccagacctacaaggccaacgacggcgcgttcgtgcgcgagcac
ttcttcggccgcgacccgcggacgaaggaactggtcaaggacctgtccgaccagcagatc
tggaacctcaagcgcggtggccacgactaccgcaagatctacgcggcctacaaggcggcg
atggagcacaagggtcagccgacggtgatcctcgcgcacaccatcaagggctacacgctc
ggtaagcacttcgagggccgcaacgcgacccaccagatgaagaagctcaccctcgaggac
ctcaagtacttccgcgacatccagcggatcccgatctcggacgaagagctcgagaaggat
ccgaagatgccgccgtactaccaccccggcttcgagtcgcccgagatccagtacatgctc
gagcgtcgccgggccctcggcggtttccttccggagcgccgcaccaccgcgaagccgttg
gcgctgcccgcggagaagacctacgacgtcgtccgcaagggttcgggcaagcaggaggtc
gccaccaccatggcgacggtccgtgtgctcaaggaactgttgcgcgacaaggagatcggc
aagcgcatcgtgccgatcatcccggacgaggcccgcaccttcggtatggactcgtggttc
ccgtcgctgaagatctacaaccgcaacggtcagctgtacacctcggtcgacgccgatctg
atgcttgcctacaaggagagcgaagtcgggcagatcctgcacgagggcatcaacgaggcc
ggttcgacggcgtcgttcacggcggtcgggacgtcctacgcaacgcagggcgagccgatg
atccctgtgtacatcttctactcgatgttcggtttccagcgcacgggcgacggcctgtgg
gcggcggccgaccagatggcacgcgggttcgccctcggcgcgacggccggtcgcaccacg
ctgaccggtgagggcctgcagcacgccgacgggcactcgctgctgctcgcgtcgaccaac
ccggccgcggtcacctacgacccggcgttctcctacgagatcgcccacatcttccgcgac
ggtctgcggcggatgtacggcggcacggagggtgtcgacggcttcggcggtgaggacgtc
ttttactacatcaccatctacaacgagccgtactcgcagccggccgagccggaggatctc
gacgtcgagggccttctcaagggcatctacctgtacaagcggggaccggagtcgggtccg
aaggcgcagatcctggtctcgggcgtgatgatgcccgaggcgctgcgtgcgcagaagatg
ctcgccgacgaatggggagtgtccgcggacgtctggtccgtcacttcgtggggcgagctg
cgccgcgacggcgtcgagtgcgaccgccaggcgctgctgaaccccggtgaggaagcctcg
gtgccgtacgtcgcgtcggtgctcaacgacgcggcgggtccgttcgtcgcggtgtccgac
tggatgcgcgcggtgcccgatcagatccgcaagtgggttccgggcgactacacggtgctc
ggcgccgacggcttcggcttctccgacacccgtggcgccgcccgccgcgtgttcaacatc
gacgccgagtccacggtggtcgcggtgctctcggcactcggccgcgaaggcgcgatcgat
cgtgagaaggccgtcgaggcggcccgcacctacaagatcgacgacgtgacggccgccccg
gtctcgatggcggatccgggcgtcgcctga
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