Rothia kristinae: I6G21_00205
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Entry
I6G21_00205 CDS
T06977
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
rkr
Rothia kristinae
Pathway
rkr00020
Citrate cycle (TCA cycle)
rkr00630
Glyoxylate and dicarboxylate metabolism
rkr00785
Lipoic acid metabolism
rkr01100
Metabolic pathways
rkr01110
Biosynthesis of secondary metabolites
rkr01120
Microbial metabolism in diverse environments
rkr01200
Carbon metabolism
rkr01210
2-Oxocarboxylic acid metabolism
Module
rkr_M00009
Citrate cycle (TCA cycle, Krebs cycle)
rkr_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
rkr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
I6G21_00205
00630 Glyoxylate and dicarboxylate metabolism
I6G21_00205
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
I6G21_00205
Enzymes [BR:
rkr01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
I6G21_00205
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
I6G21_00205
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
I6G21_00205
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
I6G21_00205
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Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QPT53686
UniProt:
A0A7T3CGE7
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All DBs
Position
46730..50542
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AA seq
1270 aa
AA seq
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MPDQPQHQIPEEFAGNEWLVDELFEKYQQDRNAVDEKWWPIFEQMQAAESGKRGVDAAAP
AAKTSSAKAPAEKASPDRAPQRSSGAAAKASAPAEQPEARTGAGKKETEAPKQAGTREKR
SGQKPIPAQLPHSEREEQEESQDRVTALRGPAKAIASNMEESLQVPTATTVRAVPAKVLI
DNRTMINDYLRRSRGGKISFTHLIGYAVIKALKEFPSQNVTYGQDEKGRPAVVQHAHVNF
GLAIDMPRPDGSRNLVVPNIKAAETLNFAEFWAAYDEMVTKARENKLSVEDFKGTTASLT
NPGGIGTVHSVPRLSAGQACIIGVGALDYPAERRGSSPKVLAREGVSKILTLTSTYDHRV
IQGAGSGEFLKLVDQYLQGEHGFYDEIFEVLRIPYEPVRWAVDNQVNPETEINKVARIQQ
LIHAYRVRGHLIAETNPLEYVMRKHPDLNIATYGLTLWDLDREWPTGGFGDASRLPLRTI
LQLLRDAYCGTLAVEYMHIESPQEREWFQQQLEHGYTKPSREEQLRVLGKLNAAEAFETF
LQTKFIGQKRFSLEGGESLIPLLDSIISGAADSGLAGVGIGMAHRGRLNVLSNIAGKSYA
QIFREFEGEQDPRLVGGSGDVKYHLGTEGVFTSDSGNETQVYLAANPSHLEAVDPVLEGI
VRAKQDLLDQGAEGEAAYGVLPILVHGDAAMAGQGIVAETMQMSQLRGFTVGGTVHIVVN
NQVGFTTTPGEGRSSTYATDVARMVQAPVFHVNADDPEAVVRVGRLAFEYRQRFHRDVVI
DLLCYRRRGHNEADDPSMTQPQMYQLIEAKRSTRKLYTESLVGRGDITQEEADRALKDYQ
ERLERVFKETHEAQQSKAPLVTGDAAAVSNIERPAAQQIEDSVYTPETTAIPAEAVARVG
QAHGQAPEGFQVHKKLGQLLKKRQQMAEQGGIDWGMGELIAFGSLLMDGFQIRMSGQDVQ
RGTFTQRHSVLHDTRSNAEWVPLTHLSEDQGKFMIYNSLLSEYGVLGFEYGYSVERPDSL
VVWEAQFGDFFNGAQTIIDEFISSAEQKWAQRSSLVLMLPHGYEGMGPDHSSARMERFLQ
LCAESNMTVAVPSTPANHAHLLRRQAYSRPHRPLVIMTPKQLLRLKAATSSVEDFTQGEF
QEVIPDQGGLTDAAVTKVVLVSGRLYYDLAARREKLGRQDVAIVRVEQLYPLPADQIKEQ
LARYAGAEVIWAQDEPANQGQWPFMVVNLLPLLDRQVRLISRPASASPATGVGKRHQAEL
EHLVAQIFES
NT seq
3813 nt
NT seq
+upstream
nt +downstream
nt
gtgccagatcagccacagcaccagatccccgaggagttcgccggcaacgaatggctcgtg
gacgagctgttcgagaagtaccagcaggaccggaacgccgtggacgagaagtggtggccc
atcttcgagcagatgcaggccgcggagtccggcaagcgcggtgtcgacgccgcagccccc
gccgcgaagacctcctccgcgaaggcccccgctgagaaggcctcccccgatcgcgccccg
cagcgctcgtcgggtgcggcggcgaaggcgtcggcccccgccgaacagccggaggcccgc
accggggcgggcaagaaggagaccgaggcgcccaagcaggccgggacccgggagaagcgc
tccgggcagaagccgatcccggcccagctgccgcacagcgagcgcgaggagcaggaggag
tcccaggaccgggtcaccgccctgcgcggaccggccaaggcgatcgcgtcgaacatggag
gagtccctccaggtgcccaccgcgaccacggtgcgcgccgtgccggcgaaggtgctcatc
gacaaccgcaccatgatcaacgactacctgcgccgctcccggggcgggaagatctccttc
acccacctcatcggctacgccgtgatcaaggcgctgaaggagttcccctcccagaacgtc
acctacggccaggacgagaagggccgccccgccgtcgtgcagcacgcgcacgtgaacttc
gggctggccatcgacatgccccgcccggacggctcccgcaacctcgtggtgccgaacatc
aaggccgccgagaccctgaacttcgccgagttctgggccgcctacgacgagatggtcacc
aaggcccgggagaacaagctctccgtggaggacttcaagggcaccaccgcctccctgacc
aacccgggcggcatcggcacggtgcactcggtgccgaggctgtcggccgggcaggcctgc
atcatcggcgtcggggccctggactacccggccgagcgccgcggctcctcccccaaggtg
ctggcccgggagggcgtgtccaagatcctgacgctgacctccacctacgaccaccgcgtg
atccagggggccggctccggggagttcctgaagctggtggaccagtacctgcagggcgag
cacgggttctacgacgagatcttcgaggtcctgcgcatcccctacgagccggtgcgctgg
gccgtggacaaccaggtcaacccggagacggagatcaacaaggtcgcccggatccagcag
ctgatccacgcctaccgggtgcgcggacacctcatcgcggagaccaacccgctcgagtac
gtgatgcgcaagcacccggacctgaacatcgccacctacgggctgaccctgtgggatctg
gaccgggagtggcccaccggcgggttcggggacgcctcccggctgccgctgcgcaccatc
ctgcagctgctgcgcgacgcctactgcggcacgctggccgtggagtacatgcacatcgag
tccccgcaggagcgggagtggttccagcagcagctggagcacggctacaccaagcccagc
cgcgaggagcagctgcgggtgctgggcaagctcaacgccgcggaggccttcgagaccttc
ctgcagaccaagttcatcgggcagaagcgcttctccctggagggcggggagtccctgatc
ccgctgctggactccatcatctcgggggccgcggacagcggcctggccggggtcggcatc
gggatggcccaccgcgggcgcctgaacgtgctgagcaacatcgccgggaagtcctacgcg
cagatcttccgcgagttcgagggcgagcaggacccgcgcctggtcggcggctccggggac
gtgaagtaccacctgggcaccgagggcgtgttcacctcggattccgggaacgagacccag
gtgtacctggccgcgaacccctcccacctggaggccgtggatccggtgctggaggggatc
gtgcgggccaagcaggacctgctggaccagggtgcggagggcgaggccgcctacggcgtg
ctgcccatcctggtgcacggggacgcggcgatggccgggcagggcatcgtcgccgagacc
atgcagatgtcccagctgcgcgggttcacggtgggcggcacggtgcacatcgtggtcaac
aaccaggtcggcttcaccacgacccccggtgagggccgctcctcgacctacgccaccgac
gtcgcccggatggtccaggcccccgtcttccacgtcaacgcggatgacccggaggccgtg
gtgcgcgtgggccggctggccttcgagtaccgccagcgcttccaccgcgacgtcgtcatc
gacctgctgtgctaccggcgccgcggacacaacgaggccgacgacccctcgatgacccag
ccgcagatgtaccagctgatcgaggccaagcgctcgacccgcaagctgtacaccgagtcc
ctggtgggccgcggggacatcacccaggaggaggcggaccgggcgctgaaggactaccag
gagcgcctggagcgggtcttcaaggagacccacgaggcccagcagtccaaggcgcccctg
gtcaccggggacgcggccgcggtgtcgaacatcgagcgtccggcggcccagcagatcgag
gactccgtgtacaccccggagaccacggcgatcccggccgaggccgtggcccgcgtcggg
caggcccacgggcaggcccccgagggcttccaggtgcacaagaagctgggtcagctgctg
aagaagcgccagcagatggccgagcagggcgggatcgactggggcatgggcgagctgatc
gccttcggctcgctgctgatggacggcttccagatccgcatgtccgggcaggacgtgcag
cgcgggacgttcacccagcgccactcggtcctgcacgacacccgctccaacgccgagtgg
gtgccgctgacgcacctgtccgaggaccagggcaagttcatgatctataactccctgctc
tccgagtacggggtgctgggcttcgagtacggctactccgtggagcgcccggactcgctg
gtggtgtgggaggcgcagttcggcgacttcttcaacggcgcccagacgatcatcgacgag
ttcatctcctcggccgagcagaagtgggcccagcgctcctcgctggtgctgatgctgccg
cacggctacgaggggatgggtccggatcactcctcggcgcgcatggagcggttcctgcag
ctgtgcgcggagtcgaacatgaccgtcgcggtgccctcgaccccggccaaccacgcgcac
ctgctgcgccggcaggcctactcccgcccgcaccgtccgctggtgatcatgacgccgaag
cagctgctgcgcctgaaggccgcgacctcctcggtcgaggacttcacccagggtgagttc
caggaggtcatcccggatcagggcgggctgaccgacgccgcggtgacgaaggtcgtgctg
gtctccgggcggctgtactacgacctggccgcccgccgggagaagctgggccgccaggat
gtggcgatcgtgcgggtcgagcagctgtacccgctgccggcggatcagatcaaggagcag
ctggcccgctacgccggggccgaggtgatctgggcccaggatgagcccgccaaccagggt
cagtggcccttcatggtggtcaacctgctgccgctgctggatcggcaggtgcggctcatc
tcccgtccggcctcggcctcccccgccaccggggtgggcaagcgccaccaggccgagctg
gagcacctggtcgcccagatcttcgagagctga
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