KEGG   Rhodothermus marinus SG0.5JP17-172: Rhom172_2432
Entry
Rhom172_2432      CDS       T01606                                 
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
rmg  Rhodothermus marinus SG0.5JP17-172
Pathway
rmg00270  Cysteine and methionine metabolism
rmg00450  Selenocompound metabolism
rmg00670  One carbon pool by folate
rmg01100  Metabolic pathways
rmg01110  Biosynthesis of secondary metabolites
rmg01230  Biosynthesis of amino acids
rmg04980  Cobalamin transport and metabolism
rmg04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:rmg00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    Rhom172_2432
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    Rhom172_2432
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    Rhom172_2432
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    Rhom172_2432
   04980 Cobalamin transport and metabolism
    Rhom172_2432
Enzymes [BR:rmg01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     Rhom172_2432
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: AEN74325
LinkDB
Position
2775835..2779545
AA seq 1236 aa
MRDTHPLARLLQERILILDGAMGTMIQRHRLSEEDFRGARFADHPHPLRGNNDLLVLTQP
ELIRDIHRAYLEAGADLIETNTFNANAISQADYGLEHLVYELNVAAARLAREAADEFTRR
TPERPRFVAGAIGPTNKTLSISPDVNNPAYRAVTFDEMVAVYREQVRGLLDGGVDVLLVE
TVFDTLNCKAALFAIQEEFRARARAVPVMVSGTIVDQSGRTLSGQTPEAFWISIAHMPHL
LSVGLNCALGSGQMRPFIEELARVATVFTSLYPNAGLPDELGQYRETPEYMAAQLADYAR
EGWLNLAGGCCGTTPEHIRAIAEALEGIPPRRIPEVPRTLRLSGLEPLVFRPDLNFVNIG
ERTNVTGSRRFARLIREGRYEEALDVAREQVENGAQMIDVNMDEGLLDGVQAMTTFLNLI
ATEPEIARVPVVIDSSKWEVIEAGLKCLQGKGVVNSLSLKDGEEVFKERARRVRQYGAAV
IVMAFDEQGQADTLERRIEICRRAYRILTEEVGFPPEDIIFDPNIYAVATGIPEHNRYAI
DFLEATRWIKTNLPYARVSGGISNLSFSFRGNEPVRRAMHTVFLYHAVQAGMDMGIVNPG
QLGIYEEIDPELRERIEDVLFDRRPDATERLIALAQTLTQSAADAAESETLAWRQAPVEE
RLRHALVKGITEFIEEDVEEARQKYGSPLAVIEGPLMDGMNVVGDLFGAGKMFLPQVVKS
ARVMKKAVAYLVPFLEAEKQKLGDTRPRARILLATVKGDVHDIGKNIVGVVLQCNGFEVI
DLGVMVPADRILEEARRHRVDLIGLSGLITPSLDEMVHVARELERAGFDTPLLIGGATTS
KVHTALKIDPCYHAPVVHVLDASRAVPVASALVDPDRRDAFAEEIRQEYEAIRRRHGRRT
DEQLLTIEEARANRFTCDWSAVPIMRPNRPGLTVFRNYPLAEIRRYIDWTPFFQAWELRG
KYPRILDDPKKGPEARRLFADANQLLDEIIAHGWLQAHGVVGLFPANSQGDDVLVFADEA
RRKVRAVLHFLRQQTPKRTGQPNRSLADYVAPVESGRADYIGAFAVTAGHGLEELVARFE
RAHDDYQAILAKALADRLAEAFAELLHERVRRELWGYAPDERLTNEELIAERYRGIRPAP
GYPACPDHTEKWTLWELLEAERHTGIRLTEHLAMHPAASVCGYYLAHPEASYFNVGHLGM
DQIEDYARRKGMTVEEVERWLAPRLAYDPAARADAA
NT seq 3711 nt   +upstreamnt  +downstreamnt
atgcgcgacacgcacccgctagcccggctacttcaggagcggattctgatcctcgacggg
gcgatgggcacgatgatccagcgccatcgcctctcggaagaagacttccgcggcgcgcgc
tttgccgaccatccccatccgctgcggggcaacaacgacctgctcgtcctgacgcaaccc
gaactgatccgcgacatccaccgcgcctatctcgaagcgggtgccgacctgatcgaaacg
aacaccttcaacgccaacgccatctcgcaggccgactacgggctggagcacctggtctat
gaactcaacgtggcggccgcgcgcctggcccgcgaggctgccgacgaatttacgcgccgc
acccccgagcgcccccgcttcgtggccggtgccatcggccccacgaacaagacgctttca
atctcgcccgacgtcaacaatccggcctaccgggccgtcaccttcgacgaaatggtggcc
gtctatcgggagcaggtgcgcgggctgctcgacggcggcgtcgatgtgctgctcgtcgag
accgtcttcgacacgctcaactgcaaggcggcgctctttgccattcaggaagaatttcgc
gcgcgcgcccgggccgtgcccgtcatggtctcgggcacgatcgtggaccagagcggccgt
acgctttcgggccagacgcccgaggccttctggatttccattgcgcacatgccgcacctg
ctttcggtgggactcaactgtgcgctcggctccggccagatgcgtccgttcatcgaggag
ctggcccgtgtggccaccgtcttcaccagcctctacccgaacgccgggctgcccgatgaa
ctcggtcagtatcgcgaaacgcccgagtacatggccgcgcaactggccgattacgcccgc
gagggctggctcaacctggccggcggctgctgcggcaccacgcccgagcacatccgcgcc
atcgccgaggcgctcgaaggcattccgccccgccgcatccccgaggtgccgcgcacgctg
cgcctttcgggcctggagccgctcgtcttccgacccgacctgaacttcgtcaacatcggc
gaacggacgaacgtcacgggctcgcgccgcttcgcccgcctgatccgcgagggtcgctac
gaagaagcgctcgacgtggcccgcgaacaggtggaaaacggcgctcagatgatcgacgtg
aacatggacgagggcctgctcgacggcgtgcaggccatgaccacgttcctgaacctgatc
gccaccgagccggaaatcgcccgcgtgcccgtggtgatcgactcgtcgaagtgggaggtg
atcgaagccgggctgaagtgcctgcagggcaagggcgtcgtcaactcgctttcgctcaaa
gacggcgaggaggtcttcaaggaacgcgcccggcgcgtgcgccagtacggggcggccgtc
atcgtgatggccttcgacgagcagggccaggccgacacgctcgaacgccgcatcgaaatc
tgccgccgcgcctaccgcatcctgaccgaagaggtcggctttccgcccgaagacatcatc
ttcgacccgaacatttacgccgtcgccaccggcatcccggagcacaaccgctacgccatc
gactttctggaggccacgcgctggatcaagacgaacctgccctacgcgcgcgtctcgggc
ggcatctcgaacctgtcgttttcgttccggggcaacgagccggtccgccgggccatgcac
acggtgtttctctaccacgccgtgcaggccggcatggacatgggcatcgtcaaccccggc
cagctcgggatctacgaagaaatcgatcccgagctgcgcgagcgcatcgaagacgtgctc
ttcgaccgccggcccgatgccaccgagcgtctgatcgcgctggcccagacgctgacgcaa
tcggccgccgacgccgccgagtccgaaacgctggcctggcgccaggcgcccgtcgaggag
cggctgcgccatgcgctcgtcaagggcatcacggagttcatcgaagaagacgtcgaggaa
gcccgccagaagtacggctcgccgctggccgtcatcgaagggccgctcatggacgggatg
aacgtggtgggcgacctgttcggcgcgggcaagatgttcctgccccaggtggtcaaaagc
gcccgcgtgatgaagaaggccgtggcctatctggtgcccttcctggaggccgaaaagcag
aaactgggcgacacgcggccgcgcgcccgcatcctgctggccacggtcaaaggcgacgtg
cacgacatcggcaagaacatcgtgggcgtggtgctccagtgcaatggcttcgaggtgatc
gacctgggtgtaatggtgcccgccgaccgcatcctcgaagaggcccgccgccaccgggtg
gacctgatcggcctgagcgggctgatcacgccgagcctcgacgagatggtgcacgtagcc
cgcgagctggagcgggccggcttcgacacaccgctgctgatcggcggcgctacgacctcg
aaggtgcacacagccctgaagatcgatccctgctaccacgcgcccgtcgtgcacgtgctc
gatgcctcgcgggccgtgccggtggccagcgcccttgtcgatccggaccgtcgtgatgcc
tttgcagaagaaatccgccaggagtacgaggcgatccgacggcgccacggtcgccgcacc
gacgagcaactactgaccatcgaagaagcgcgggccaaccgcttcacgtgtgactggtcg
gccgtgccgattatgcgcccgaaccgtccgggcctgaccgtcttccgcaactacccgctg
gcggagatccggcgctatatcgactggacgccgttcttccaggcctgggagctgcgcggc
aagtatccgcgcattctggacgacccgaaaaaaggtcccgaggcgcgacggctgtttgcc
gacgccaaccagctactggacgaaatcatcgcgcacggctggttgcaggcgcacggtgtc
gtcggactgtttccggccaacagccagggcgacgacgtgctggtgttcgccgacgaagcg
cgtcgcaaggtgcgggccgtgctgcacttcctgcgccagcagacccccaagcggacaggc
cagcccaaccgctcgctggccgactacgtggcgcccgtcgagagcggccgcgccgactac
atcggagccttcgccgtgacggccggccacgggctggaagaactggtggcccgcttcgag
cgcgcccacgacgactaccaggccattctggccaaagcgctggccgatcgcctggccgag
gcgttcgccgagctactgcacgaacgcgtccggcgcgagctgtggggctatgcgcccgac
gaacggctgacgaacgaggaactgattgccgagcgctaccgcggaattcgtccggcaccc
ggctatccggcctgtcccgaccacacggagaagtggacgctctgggagttgctggaggcc
gaacgccacacgggcattcggctcaccgagcatctggccatgcacccggccgcgtccgtg
tgcggctactacctggctcatcccgaggcgtcctatttcaacgtgggacacctgggtatg
gaccagatcgaagactacgcccggcgcaagggcatgaccgtcgaggaagtcgaacgctgg
ctggctccacgcctggcctacgacccggccgcccgcgccgacgccgcgtga

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