Rattus norvegicus (rat): 100364027 Help Entry 100364027         CDS       T01003                                  Symbol Hkdc1 Name (RefSeq) hexokinase HKDC1 isoform X1   KO K00844   hexokinase [EC:2.7.1.1] Organism rno  Rattus norvegicus (rat) Pathway rno00010   Glycolysis / Gluconeogenesis rno00051   Fructose and mannose metabolism rno00052   Galactose metabolism rno00500   Starch and sucrose metabolism rno00520   Amino sugar and nucleotide sugar metabolism rno00524   Neomycin, kanamycin and gentamicin biosynthesis rno01100   Metabolic pathways rno01200   Carbon metabolism rno01250   Biosynthesis of nucleotide sugars rno04066   HIF-1 signaling pathway rno04910   Insulin signaling pathway rno04930   Type II diabetes mellitus rno04973   Carbohydrate digestion and absorption rno05230   Central carbon metabolism in cancer Module rno_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate rno_M00549   Nucleotide sugar biosynthesis, glucose => UDP-glucose rno_M00892   UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc Brite KEGG Orthology (KO) [BR:rno00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     100364027 (Hkdc1)    00051 Fructose and mannose metabolism     100364027 (Hkdc1)    00052 Galactose metabolism     100364027 (Hkdc1)    00500 Starch and sucrose metabolism     100364027 (Hkdc1)    00520 Amino sugar and nucleotide sugar metabolism     100364027 (Hkdc1)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     100364027 (Hkdc1)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     100364027 (Hkdc1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     100364027 (Hkdc1)   09154 Digestive system    04973 Carbohydrate digestion and absorption     100364027 (Hkdc1)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     100364027 (Hkdc1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     100364027 (Hkdc1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:rno04131]     100364027 (Hkdc1) Enzymes [BR:rno01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      100364027 (Hkdc1) Membrane trafficking [BR:rno04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     100364027 (Hkdc1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 VPS13_mid_rpt CSD Motif Other DBs NCBI-GeneID:  100364027 NCBI-ProteinID:  XP_038955090 RGD:  2321830 Ensembl:  ENSRNOG00000049045 LinkDB All DBs Position 20:complement(30878037..30917044) Genome browser AA seq 915 aa AA seqDB search MFAVHLVAFYFTKLKEDQIKKVDRFLYHMRLSDETLVDIMARFQAEMEKGLGKDTNPTAS VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVSEEGKQNVQMESQFYPMPNEITR GNGTELFDYVADCLADFMKTKDLTHKKLPLGFTFSFPCRQNKLEEGFLLSWTKKFKARGV QDTDVVNRLATAMKKHKDLDVDILALVNDTVGTMMTCAYDDPNCEVGVIIGTGTNACYME DMSNIDLVEGDEGRMCINTEWGAFGDDGTLEDIRTEFDRELDLGSLNPGKQLFEKMISGL YMGELVRLILLKMAKVGLLFGGAKSSALHTKGKIETQHVAAMEMSKEGLANTREILVDLG LDPSESDCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKLARLRTTVGMDGTLYKTH PQYPKRLHKVVRRLVPNCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDKVLALFHLT REQLLGVRDKMRAELEYGLKKKTHALATVKMLPTYVYGMPDGTEKGKFLALDLGGTNFRV LLVKIRKRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGAQLPLGFTFS FPCRQTCIDKGTLVGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAIVNDTVGTMM TCGYEDPRCEIGLIAGTGSNVCYMEEMRNIELVDGDEGRMCVNTEWGGFGDNGCIDDIRT QYDKEVDEGSLNAGKQRYEKMTSGMYLGEIVRRILIDLTRQGLLFRGQISERLRTRGIFE TKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQMCGAGMAAIVE KRREDQGLQHFKVTVGVDGTLYKLHPHFSRILQETVKDLAPQCDVTFMLSEDGSGKGAAL ITAVAKRLQQLPKDN NT seq 2748 nt NT seq  +upstreamnt  +downstreamnt atgtttgcagttcacttagtggcgttttacttcaccaagctgaaagaggaccagatcaag aaggtggacaggttcctgtaccatatgcggctctcggatgagacccttgtggacatcatg gcccgattccaggccgagatggagaaaggcttagggaaggacaccaaccccactgcctca gtgaagatgctgcccacattcgtcagggccattccagatggctcagaaaacggggaattc ctttccctggatctcggagggtccaagtttcgggtcctgaaggtgcaagtctcggaagag ggcaagcaaaatgtccagatggagagccagttctacccaatgcccaatgaaatcacccgt gggaatggcacggagctctttgactatgtagctgactgcctggcagatttcatgaagacc aaagatctgacgcacaagaagctgcctctgggcttcaccttttcttttccctgcagacag aataagttggaggagggcttcctgctgtcatggaccaagaagttcaaggcccggggagtt caggacacagacgtggtgaaccgtctggccaccgccatgaaaaagcacaaggacctggac gtggacatcctggccttggttaacgacactgtggggaccatgatgacttgtgcttatgat gatcccaactgtgaggtcggcgttatcattggaacaggcaccaacgcgtgttacatggag gacatgagcaacatcgaccttgtggaaggggacgagggaaggatgtgcatcaacacggag tggggggccttcggggacgatggcactttggaggacattcgcaccgagtttgacagagag ttggacctgggctcactcaaccccgggaagcagctgttcgagaagatgatcagcgggctg tacatgggggagctggtcaggctcatcttgctgaagatggccaaagttggtctcctgttt gggggtgcaaagtcctccgctctccacacaaagggcaagattgaaacacagcacgtggct gccatggagatgagtaaagaaggcctggccaatacgagagagatcctggtggatttgggc ctggacccctctgagtcagactgcatcgctgtccagcacgtgtgcaccatcgtctctttt cgctcggccaatctctgcgccgctgcgctggcagccatcttgactcgcctccgagagaac aagaagctggcccggctccgcaccacggtgggcatggatggaaccctctacaaaacacac cctcagtaccccaaacgcctacacaaagtggtgaggaggctggtcccaaactgtgatgtc cgcttcctcctatcagagagcggaagcaccaaaggggctgccatggtgaccgcagtggcc tctcgggtgcaggcccagcgtaagcagatcgataaggtgctggctttgttccatttgacc cgagagcaactcctgggtgtgcgggacaagatgcgggctgaacttgagtatgggctgaag aaaaaaactcacgctctggctacagtgaagatgcttcccacctacgtctatgggatgccc gatggcacagagaaaggaaagttccttgccctggacttggggggaactaacttccgcgtc ctccttgtaaagatcaggaagaggtcggtgcgaatgtacaacaagatctttgccatccct ctggagatcatgcagggcactggagaggagctctttgaccacattgtgcagtgcatcgct gacttcctggactatatgggcctcaagggcgcccagctgcctttgggcttcacattctcc ttcccctgcagacaaacatgcatcgacaaggggactctagtaggatggaccaaaggcttc aaggccaccgactgtgaaggggaggacgtggtggacatgctcagagaagccatcaagagg agaaacgagtttgacctggacatagttgcaatcgtgaatgacacggtggggaccatgatg acctgtggctatgaggatccccggtgtgagattggcttgattgcagggacaggaagcaac gtgtgctacatggaagaaatgaggaacattgagctggtggacggggatgaaggccggatg tgcgtcaacacggagtggggcgggtttggcgacaacggctgcatagatgacatccgcacg cagtacgacaaggaggtggatgagggctccctgaatgccggcaaacagaggtacgagaaa atgaccagtgggatgtacctgggggagattgtgaggcggatcctgatcgacctcacccgg caggggctcctcttccgagggcagatttcagagcgactccggaccaggggtatctttgaa accaaattcctgtctcagattgaaagtgaccggctggccctcctgcaggtcaggaggatc ctgcagcagctgggcctggacagcacctgcgaagacagcattgtggtgaaggaggtgtgc ggggctgtgtctcggagggctgcccagatgtgcggcgccggcatggctgccatcgtggag aaaaggagagaagaccagggcctccagcacttcaaggtcactgtgggcgtggacggcacc ctgtacaagctgcacccacacttctcccggatactgcaggagacagtgaaggacctggct cctcagtgcgacgtgactttcatgttgtcagaagacggcagcgggaagggagcagctctg atcacagctgtagccaagaggttacagcagctgccgaaggacaactag

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