Rattus norvegicus (rat): 116689
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Entry
116689 CDS
T01003
Symbol
Ptpn6
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 6
KO
K05697
tyrosine-protein phosphatase non-receptor type 6 [EC:
3.1.3.48
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04148
Efferocytosis
rno04520
Adherens junction
rno04630
JAK-STAT signaling pathway
rno04650
Natural killer cell mediated cytotoxicity
rno04660
T cell receptor signaling pathway
rno04662
B cell receptor signaling pathway
rno05140
Leishmaniasis
rno05205
Proteoglycans in cancer
rno05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
116689 (Ptpn6)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
116689 (Ptpn6)
09144 Cellular community - eukaryotes
04520 Adherens junction
116689 (Ptpn6)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
116689 (Ptpn6)
04660 T cell receptor signaling pathway
116689 (Ptpn6)
04662 B cell receptor signaling pathway
116689 (Ptpn6)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
116689 (Ptpn6)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
116689 (Ptpn6)
09174 Infectious disease: parasitic
05140 Leishmaniasis
116689 (Ptpn6)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
rno01009
]
116689 (Ptpn6)
Enzymes [BR:
rno01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
116689 (Ptpn6)
Protein phosphatases and associated proteins [BR:
rno01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
116689 (Ptpn6)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Y_phosphatase
SH2
PTP-SAK
SH2_1
Tc-R-P
DSPc
PTPlike_phytase
Y_phosphatase3
PTP-NADK
FXMRP1_C_core
Motif
Other DBs
NCBI-GeneID:
116689
NCBI-ProteinID:
NP_446360
RGD:
620660
Ensembl:
ENSRNOG00000014294
UniProt:
P81718
Q499N7
LinkDB
All DBs
Position
4:complement(159212320..159237069)
Genome browser
AA seq
597 aa
AA seq
DB search
MLSRGWFHRDLSGPDAETLLKGRGVPGSFLARPSRKNQGDFSLSVRVDDQVTHIRIQNSG
DFYDLYGGEKFATLTELVEYYTQQQGILQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGG
QAESLLQAKGEPWTFLVRESLSQPGDFVLSVLNDQPKAGPGSPLRVTHIKVMCEGGRYTV
GGSETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESED
TAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKSKNRYKNILPFDHSRVILQGRDSNIPG
SDYINANYVKNQLLGPDENSKTYIASQGCLDATVNDFWQMAWQENTRVIVMTTREVEKGR
NKCVPYWPEVGTQRVYGLYSVTNCKEHDTAEYKLRTLQISPLDNGDLVREIWHYQYLSWP
DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMESVSTKGL
DCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEIIQSQRGQESEYGN
ITYPPALRSAHAKASRTSSKHKEEVYENVHSKNKKEEKVKKQRSADKEKNKGSLKRK
NT seq
1794 nt
NT seq
+upstream
nt +downstream
nt
atgctgtcccgcgggtggtttcaccgggacctcagtgggcctgatgccgagaccctgctc
aagggccggggagtccctgggagcttcctggctcggcccagtcgcaagaaccagggtgac
ttctccctctcagtcagggtggatgaccaggtgactcatattcggatccagaactcaggg
gacttctatgacctgtatggaggggagaagtttgcgacgttgacagagctggtggagtat
tacactcagcagcagggcatcctgcaggaccgagacggcaccatcatccacctcaagtac
ccactgaactgctcggaccccaccagcgagaggtggtatcatggtcacatgtctggaggg
caggcagagtcactgctgcaggccaagggcgagccctggacatttcttgtgcgtgagagt
ctcagccaacctggtgattttgtgctctctgtgctcaatgaccagcccaaggctggcccg
ggttccccgctcagggtcacgcacatcaaggttatgtgtgagggtggacgatacactgtg
ggtggctcagagacattcgacagcctcacagacctggtggagcacttcaagaagacgggg
attgaggaggcctcaggtgcctttgtctacctgaggcagccttactatgccactcgggta
aatgcagcagacattgagaaccgggtcttggaactgaacaagaagcaggagtcagaggac
acagccaaggccggcttctgggaggagtttgagagtctgcaaaagcaagaggtaaagaac
ttgcaccagcgtctggaagggcagcggccggagaacaagagcaagaaccgctacaagaac
attcttccctttgaccacagccgagtgatcctgcagggacgtgacagtaacatcccaggg
tctgattacatcaatgccaactacgttaagaaccagctgctaggtccggatgagaactct
aagacctacatcgccagtcagggctgtctggacgctaccgtcaatgacttctggcagatg
gcttggcaggagaacactcgtgtcatcgtcatgactaccagagaggtggagaaaggccgg
aacaaatgtgtcccatactggcctgaggtgggcactcagcgcgtctatgggctctactct
gtgaccaactgtaaagagcatgacacagcagagtacaaacttcgaacattgcagatctcc
ccactggacaatggggacctggttcgggagatatggcactaccagtacctgagctggcct
gaccatggggttcccagtgagcctggaggtgtcctcagcttcctggatcagatcaaccag
cggcaggaaagtttgcctcacgcggggcccatcattgtgcattgcagcgctggcatcggc
cgcacgggcaccatcatcgtcattgatatgctcatggagagcgtctccaccaaggggcta
gactgtgacattgacatccagaagaccatccagatggtacgggcacagcgctctggcatg
gtgcagacagaggcacagtacaagtttatttatgtggccatcgcccagttcatcgaaaca
accaagaagaaactggagatcatacaatcccagaggggccaggagtcggagtatgggaac
atcacctaccctccggctttgaggagtgcccacgccaaagcctcccgtacctcctccaaa
cacaaggaggaggtgtacgaaaacgtgcatagcaagaacaagaaggaagagaaagtaaag
aagcagcgatcggcagacaaggagaagaacaaaggttctctcaagaggaagtga
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