Rattus norvegicus (rat): 24716
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Entry
24716 CDS
T01003
Symbol
Ret
Name
(RefSeq) proto-oncogene tyrosine-protein kinase receptor Ret isoform a precursor
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04010
MAPK signaling pathway
rno04020
Calcium signaling pathway
rno04151
PI3K-Akt signaling pathway
rno05200
Pathways in cancer
rno05216
Thyroid cancer
rno05223
Non-small cell lung cancer
rno05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
24716 (Ret)
04020 Calcium signaling pathway
24716 (Ret)
04151 PI3K-Akt signaling pathway
24716 (Ret)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
24716 (Ret)
05230 Central carbon metabolism in cancer
24716 (Ret)
09162 Cancer: specific types
05216 Thyroid cancer
24716 (Ret)
05223 Non-small cell lung cancer
24716 (Ret)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rno01001
]
24716 (Ret)
Enzymes [BR:
rno01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
24716 (Ret)
Protein kinases [BR:
rno01001
]
Receptor tyrosine kinases (RTK)
RET family
24716 (Ret)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD4
RET_CLD1
RET_CLD3
Pkinase
RET_CRD
Cadherin
RIO1
Pkinase_fungal
Haspin_kinase
ABC1
Motif
Other DBs
NCBI-GeneID:
24716
NCBI-ProteinID:
NP_036775
RGD:
3556
Ensembl:
ENSRNOG00000014751
UniProt:
G3V9H8
LinkDB
All DBs
Position
4:complement(152998344..153040556)
Genome browser
AA seq
1115 aa
AA seq
DB search
MAKARSGAAGLGLKLFLLLPLLGEAPLGLYFSRDAYWERLYVDQPAGTPLLYVHALRDAP
GEVPSFRLGQYLYGVYRTRLHENDWIHIDSGTGLLYLNQSLDHSSWEQLSIRNGGFPLLT
VFLQVFLGSTAQREGECHWPGCARVYFSFINDTFPNCSSFKARDLCTPETGVSFRIRENR
PPGTFYQFRMLPVQFLCPNISVKYKLLEGDGLPFRCDPDCLEVSTRWALDRELQEKYVLE
AECAVAGPGANKEKVAVSFPVTVYDEDDSPPTFSGGVGTASAVVEFKRKEGTVVATLQVF
DADVVPASGELVRRYTSTLLSGDSWAQQTFRVEHTPNETLVQSNNNSVRATMHNYKLVLN
RSLSISESRVLQLVVLVNDSDFQGPGSGVLFLHFNVSVLPVTLNLPMAYSFPVNRRARRY
AQIGKVCVENCQEFSGVSIQYKLQPSSTNCSALGVVTSTEDTSGTLYVNDTEALRRPECT
ELQYTVVATDRQTRRQTQASLVVTVEGTYIAEEVGCPKSCAVNKRRPECEECGGLGSPTG
RCEWRQGDGKGITRNFSTCSPSTRTCPDGHCDALESRDINICPQDCLRGPIVGGHERGER
QGIKAGYGICNCFPDEKKCFCEPEDSQGPLCDELCRTVITAAVLFSFIISVLLSTFCIHR
YHKHAHKPPIASAEMTFCRPAQGFPISYSSSGTRRPSLDSMENQVSVDSFKIPEDPKWEF
PRKNLVLGKTLGEGEFGKVVKATAFRLKGRAGYTTVAVKMLKENASQSELRDLLSEFNLL
KQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRDSRKIGPAYVSSGGSRNSSSLD
HPDERVLTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDV
YEEDSYVKKSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPER
LFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKSRDYLDLA
ASTPSDSLLYDDGLSEEETPLVDCNSAPLPRSLPSTWIENKLYGMSDPNWPGESPVPLTR
ADGTSTGFPRYANDSVYANWMVSPSAAKLMDTFDS
NT seq
3348 nt
NT seq
+upstream
nt +downstream
nt
atggcgaaagcgaggtccggcgccgcagggctggggctgaagctgtttttgctgctgccg
ctactgggagaagccccgctgggtctctacttctcaagggatgcttactgggagaggctg
tatgtggaccagccagctggcacacctctgctctatgtccatgccctacgggatgcccct
ggagaagtgcccagcttccgcctgggccagtatctctatggcgtctaccgcacgcgtctg
catgagaatgactggatccacatcgattcgggcactggcctcctctacctcaatcagagc
ctggaccatagttcctgggagcagctcagcatccgcaatggcggcttccccttgctcacc
gtcttcctccaggtcttcctggggtccacagcccagagagagggagagtgtcattggcca
ggctgtgcccgtgtgtacttctccttcatcaacgacaccttcccaaattgtagctccttc
aaagcccgggatctctgcaccccggagacgggtgtgtccttccgcatcagggagaacagg
ccccctggcaccttctaccagttccgcatgctacctgtgcagttcctttgtcctaacatc
agtgtgaagtacaaactcttagaaggggacggtctgcccttccgttgtgaccccgactgt
ctggaggtgagcacgcggtgggcgctggatcgggagcttcaggagaagtatgtgctggag
gctgagtgcgcagtggcaggccctggagccaacaaggagaaggtggccgtgtccttcccg
gtgacggtgtatgatgaagacgactccccgcccaccttctccggaggtgtgggcaccgcc
agtgctgtggtggagtttaagcggaaggagggcactgtggtagccactctgcaggtgttt
gatgcagatgtggtgccagcatctggggagctggtgaggcggtacacaagcacactactc
tcaggggattcctgggcccagcagaccttccgggtggagcacacacccaacgagaccttg
gtccagtccaacaacaactccgtgcgggcaaccatgcacaattacaagctggttctcaac
aggagcctgtccatctcagagagccgagtcctgcagctagtagtcctggtcaatgactca
gacttccaggggcctgggtcaggtgttctcttcctccatttcaacgtgtctgtgctgcct
gtcaccctgaacctacccatggcctactccttcccagtgaataggagagcccgccgttat
gcccagattgggaaagtttgcgtggagaactgccaggagttcagcggtgtctccatccag
tacaagctgcagccctccagcaccaactgcagtgccctaggtgtggtcacctcaacagaa
gacacctcagggaccctatatgtaaatgacacggaggccctgcggcgacctgagtgtacc
gagcttcagtacacagtggtagccactgaccggcagacccgcaggcagacccaggcttcg
ttagtcgtcacagtggaggggacatacattgcagaagaagtgggctgccccaagtcctgt
gcagtaaacaagaggcgacctgagtgtgaggagtgtggtggcctgggttctccaactggc
agatgtgagtggcgtcagggagatggtaaagggatcaccaggaacttctccacctgttct
cctagcaccaggacctgtcctgatggccactgtgatgctctggagagccgggatatcaac
atttgcccccaggactgtctccgtggccccattgttggcgggcatgagcgaggggagcgc
caggggattaaagccggctatggcatctgcaactgtttccctgatgagaagaagtgcttc
tgcgagccagaggacagccagggcccattgtgcgatgagctgtgccgtacggtcatcaca
gccgctgtcctcttctccttcataatctctgtcctgctgtccaccttctgcatccaccgc
taccacaagcatgcgcacaagccacccatcgcgtcagccgaaatgaccttctgccggccg
gcccagggcttcccaatcagctattcttcctcgggcacccgccggccctcactggactcc
atggagaaccaggtctctgtggactctttcaagatcccggaggatccgaagtgggaattt
cctcggaagaacttagttcttgggaaaaccctgggagaaggcgagtttggaaaagtagtc
aaggccacagccttccgtctgaaaggccgggcaggatacaccacagtggctgtgaaaatg
ctgaaagaaaacgcctcccagagtgaactacgagacctgctctctgagttcaaccttctg
aaacaagtcaaccatccacatgtcatcaagttgtacggggcttgcagccaggatgggcca
cttcttctcattgtggagtatgcaaagtatggatccctgcgggggttcctgcgggacagc
cgcaagatcgggcctgcctatgtgagcagtggaggcagccgcaattccagctccctggac
cacccagacgaaagggtgctgaccatgggcgacctcatctccttcgcctggcagatctcg
aggggtatgcagtacttggctgaaatgaagctcgtacatcgagacttagctgccagaaac
atcttggtggcagagggacggaagatgaagatctctgactttgggctgtcccgagatgtt
tatgaagaagattcctatgtgaagaaaagcaagggccggattcccgtcaaatggatggca
atcgagtctctcttcgatcacatctataccactcaaagtgatgtgtggtcctttggagtg
ctgctatgggagattgtgaccctgggaggcaacccctaccctggaattcctcctgaacga
ctcttcaaccttctgaagacaggccacaggatggagaggccagacaactgcagcgaggaa
atgtaccgcctgatgctgcagtgctggaagcaggagccggacaagaggccagtatttgct
gacatcagcaaggatctggagaagatgatggtcaaaagcagagactacttggacctggct
gcatccaccccttcggactcactgctctatgacgatgggctctcggaagaggagacgccc
ctggtggactgtaacagtgctcccctcccgcgctccctcccttccacatggattgaaaac
aaactctatggcatgtcagacccgaactggcctggagagagtcctgtaccactcacgaga
gccgatggcactagcactgggttcccaagatatgcaaatgatagtgtatatgctaactgg
atggtttcaccctcagcggcaaaattaatggacacatttgatagttaa
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