KEGG   Rattus norvegicus (rat): 24861
Entry
24861             CDS       T01003                                 
Symbol
Ugt1a1
Name
(RefSeq) UDP-glucuronosyltransferase 1A1 precursor
  KO
K00699  glucuronosyltransferase [EC:2.4.1.17]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00040  Pentose and glucuronate interconversions
rno00053  Ascorbate and aldarate metabolism
rno00140  Steroid hormone biosynthesis
rno00830  Retinol metabolism
rno00860  Porphyrin metabolism
rno00980  Metabolism of xenobiotics by cytochrome P450
rno00982  Drug metabolism - cytochrome P450
rno00983  Drug metabolism - other enzymes
rno01100  Metabolic pathways
rno01240  Biosynthesis of cofactors
rno04976  Bile secretion
rno05204  Chemical carcinogenesis - DNA adducts
rno05207  Chemical carcinogenesis - receptor activation
Module
rno_M00014  Glucuronate pathway (uronate pathway)
rno_M00129  Ascorbate biosynthesis, animals, glucose-1P => ascorbate
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    24861 (Ugt1a1)
   00053 Ascorbate and aldarate metabolism
    24861 (Ugt1a1)
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    24861 (Ugt1a1)
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    24861 (Ugt1a1)
   00860 Porphyrin metabolism
    24861 (Ugt1a1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    24861 (Ugt1a1)
   00982 Drug metabolism - cytochrome P450
    24861 (Ugt1a1)
   00983 Drug metabolism - other enzymes
    24861 (Ugt1a1)
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    24861 (Ugt1a1)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    24861 (Ugt1a1)
   05207 Chemical carcinogenesis - receptor activation
    24861 (Ugt1a1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:rno01003]
    24861 (Ugt1a1)
Enzymes [BR:rno01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.17  glucuronosyltransferase
     24861 (Ugt1a1)
Glycosyltransferases [BR:rno01003]
 Others
  Hydrophobic molecule
   24861 (Ugt1a1)
SSDB
Motif
Pfam: UDPGT EryCIII-like_C Glyco_tran_28_C Glyco_transf_4 Pox_A14
Other DBs
NCBI-GeneID: 24861
NCBI-ProteinID: NP_036815
RGD: 3935
Ensembl: ENSRNOG00000018740
UniProt: Q64550 Q547Q8 Q5DT04
LinkDB
Position
9:96249143..96256264
AA seq 535 aa
MSVVCRSSCSLLLLPCLLLCVLGPSASHAGKLLVIPIDGSHWLSMLGVIQQLQQKGHEVV
VIAPEASIHIKEGSFYTMRKYPVPFQNENVTAAFVELGRSVFDQDPFLLRVVKTYNKVKR
DSSMLLSGCSHLLHNAEFMASLEQSHFDALLTDPFLPCGSIVAQYLSLPAVYFLNALPCS
LDLEATQCPAPLSYVPKSLSSNTDRMNFLQRVKNMIIALTENFLCRVVYSPYGSLATEIL
QKEVTVKDLLSPASIWLMRNDFVKDYPRPIMPNMVFIGGINCLQKKALSQEFEAYVNASG
EHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQN
DLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEM
TADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAA
HDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH
NT seq 1608 nt   +upstreamnt  +downstreamnt
atgtccgtggtgtgccggagctcatgttcgcttctgcttcttccgtgccttctgctgtgt
gtgttgggtccctctgcgtcccatgctgggaagctgttagtgatccccatagatggcagc
cactggctgagtatgctcggagttattcagcagctccagcaaaaggggcacgaagtggtg
gtcatagcacctgaagcttcgatacacataaaagaaggatcattttacactatgaggaag
taccctgtgccattccaaaatgaaaacgtgacagctgcttttgtggaacttgggcggagt
gtctttgatcaagatccttttctgctgcgtgtggttaaaacatacaacaaagtcaaaagg
gactccagtatgctgctgtctggctgctcccaccttctgcacaatgccgagtttatggcc
tctctggaacaaagccactttgatgctctgctgacagaccctttccttccgtgtggctcc
attgtggcccagtacctgtctctgcctgctgtgtacttcttgaatgcattgccatgcagc
ctggatttggaagccacccaatgccctgctccgttgtcctacgtgcccaagagtttgtcc
tcgaacacagatcgcatgaacttcctgcagcgggtgaagaacatgattattgctttgaca
gagaactttctatgcagagtggtttactccccctatgggtcacttgccactgaaatctta
cagaaagaggtgactgtcaaggaccttctgagtcctgcatctatctggctgatgagaaac
gactttgtgaaagattaccccaggcccatcatgcccaacatggtttttattggtgggata
aactgccttcagaaaaaagccctatcccaggaatttgaagcctatgtcaacgcctccgga
gaacatggcatcgtggttttctctttgggatccatggtctcagagattccagagaagaaa
gcgatggaaattgctgaggctttgggcagaattcctcagacggtcctgtggcgctacacc
ggaactagaccatcgaaccttgcaaagaacactattcttgtcaaatggctaccccaaaac
gatctgcttggtcatccaaaggctcgggcgttcatcacacactccggttcccatggtatt
tatgaaggaatatgcaatggggttccaatggtgatgatgcccttgtttggtgatcagatg
gacaacgccaagcgcatggaaactcggggagctggggtgaccctgaatgtcctggaaatg
actgccgatgatttggaaaacgcccttaaaactgtcatcaataacaagagttacaaggag
aacatcatgcgcctctccagccttcacaaggaccgtcctatcgagcctctggacctggct
gtgttctgggtggagtacgtgatgaggcacaagggggcgccacacctgcgccccgccgcc
cacgacctcacctggtaccagtaccactccttggacgtgattggctttctcctggccatc
gtgttgacggtggtcttcattgtctataaaagttgtgcctatggctgccggaaatgcttt
gggggaaagggtcgagtgaagaaatcacacaaatccaagacccactga

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