Rattus norvegicus (rat): 24954 Help Entry 24954             CDS       T01003                                  Symbol Insr Name (RefSeq) insulin receptor preproprotein   KO K04527   insulin receptor [EC:2.7.10.1] Organism rno  Rattus norvegicus (rat) Pathway rno04010   MAPK signaling pathway rno04014   Ras signaling pathway rno04015   Rap1 signaling pathway rno04022   cGMP-PKG signaling pathway rno04066   HIF-1 signaling pathway rno04068   FoxO signaling pathway rno04072   Phospholipase D signaling pathway rno04081   Hormone signaling rno04150   mTOR signaling pathway rno04151   PI3K-Akt signaling pathway rno04152   AMPK signaling pathway rno04211   Longevity regulating pathway rno04213   Longevity regulating pathway - multiple species rno04520   Adherens junction rno04910   Insulin signaling pathway rno04913   Ovarian steroidogenesis rno04923   Regulation of lipolysis in adipocytes rno04930   Type II diabetes mellitus rno04931   Insulin resistance rno04932   Non-alcoholic fatty liver disease rno04960   Aldosterone-regulated sodium reabsorption rno05010   Alzheimer disease rno05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:rno00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     24954 (Insr)    04014 Ras signaling pathway     24954 (Insr)    04015 Rap1 signaling pathway     24954 (Insr)    04066 HIF-1 signaling pathway     24954 (Insr)    04068 FoxO signaling pathway     24954 (Insr)    04072 Phospholipase D signaling pathway     24954 (Insr)    04022 cGMP-PKG signaling pathway     24954 (Insr)    04151 PI3K-Akt signaling pathway     24954 (Insr)    04152 AMPK signaling pathway     24954 (Insr)    04150 mTOR signaling pathway     24954 (Insr)   09133 Signaling molecules and interaction    04081 Hormone signaling     24954 (Insr)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     24954 (Insr)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     24954 (Insr)    04923 Regulation of lipolysis in adipocytes     24954 (Insr)    04913 Ovarian steroidogenesis     24954 (Insr)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     24954 (Insr)   09149 Aging    04211 Longevity regulating pathway     24954 (Insr)    04213 Longevity regulating pathway - multiple species     24954 (Insr)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     24954 (Insr)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     24954 (Insr)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     24954 (Insr)    04932 Non-alcoholic fatty liver disease     24954 (Insr)    04931 Insulin resistance     24954 (Insr)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:rno01001]     24954 (Insr)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:rno04090]     24954 (Insr) Enzymes [BR:rno01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      24954 (Insr) Protein kinases [BR:rno01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    24954 (Insr) CD molecules [BR:rno04090]  Proteins   24954 (Insr) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Ig_DSCAM-DSCAML_C Kinase-like DUF4476 Motif Other DBs NCBI-GeneID:  24954 NCBI-ProteinID:  NP_058767 RGD:  2917 Ensembl:  ENSRNOG00000029986 Vega:  OTTRNOG00000001719 UniProt:  A0A9K3Y780 T2CB11 LinkDB All DBs Position 12:complement(5991135..6129275) Genome browser AA seq 1384 aa AA seqDB search MGSGRGCETTAVPLLMAVAALLVGTAGHLYPGEVCPGMDIRNNLTRLHELENCSVIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDVCPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHKECL GNCSEPDDPTKCVACRNFYLDGQCVETCPPPYYHFQDWRCVNFSFCQDLHYKCRNSRKPG CHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCQILEGEKTIDSVTSAQELRGC TVINGSLIINIRGGNNLAAELEANLGLIEEISGFLKIRRSYALVSLSFFRKLHLIRGETL EIGNYSFYALDNQNLRQLWDWNKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIALKTNGDQASCENELLKFSFIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPQRSNDPKSQTPSHPGWLMRGLKPWTQYAIFVKTLVT FSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVY WERQAEDSELFELDYCLKGLKLPSRTWSPPFESDDSQKHNQSEYDDSASECCSCPKTDSQ ILKELEESSFRKTFEDYLHNVVFVPRKTSSGNGAEDTRPSRKRRSLEEVGNVTATTPTLP DFPNISSTIAPTSHEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPEERCSVAA YVSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHL CVSRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKII IGPLIFVFLFSVVIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPSSVYVPDEWEV PREKITLLRELGQGSFGMVYEGNAKDIIKGEVETRVAVKTVNESASLRERIEFLNEASVM KGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSHLRSLRPDAENNPGRPPPTLQEMIQ MTAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLL PVRWMSPESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDPP DNCPERLTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFYSEENKAPESEELE MEFEDMENVPLDRSSHCQREEAGCREGGSSLSIKRTYDEHIPYTHMNGGKKNGRVLTLPR SNPS NT seq 4155 nt NT seq  +upstreamnt  +downstreamnt atgggctccgggagaggatgtgagacgacggcggtgccgttgctgatggccgtggccgcg ttgctggtgggcacagccggccacctgtaccctggagaggtgtgcccgggaatggacatc cggaacaacctgaccaggttgcatgagctggagaactgctcggtcattgagggccatctg cagatcctcttgatgttcaagaccagacccgaagatttccgagacctcagtttccccaaa ctcatcatgatcacagactacctgcttcttttccgtgtctatggcctagaaagtctaaaa gacctcttcccaaacctcacagtcatccgaggctcccgtctcttcttcaactatgccctg gtcatcttcgagatggtccacctgaaggagctgggtctttacaacctcatgaacatcacc cggggctctgtccgcatcgagaagaataatgaactctgctacctggccactatcgactgg tcccgcatcctggattccgtggaggacaactacattgtactgaacaaagatgacaatgag gaatgtggggacgtctgtccaggcacagccaagggcaagaccaactgccctgccaccgtc atcaatgggcagtttgtggaacggtgctggacacacagtcattgtcagaaagtttgccca accatctgtaagtcacatggctgcacagctgaaggcctgtgctgtcacaaggagtgcctg ggcaactgttcagaacccgatgaccctaccaagtgtgtggcctgtcgaaacttctacctg gatggtcagtgtgtggagacctgcccaccaccctactatcacttccaggattggcgctgt gtaaacttcagcttctgccaagaccttcactacaaatgcaggaactctcggaagcctggc tgtcaccaatacgtcattcacaacaacaagtgcatccccgagtgcccgtctggctatacc atgaattccagcaacttgatgtgcaccccgtgtctgggaccctgtcctaaggtctgccaa atcctcgaaggcgagaagaccattgattccgtgacatctgcccaggagctccgaggctgc actgtgatcaatggcagcctgattatcaacatccgagggggcaacaacctggcagctgaa ctagaggctaaccttggcctcattgaagaaatctcagggttcctaaagatccgtcgctcc tatgctctggtgtcactttctttcttcaggaagctacatctgattcgaggagagaccttg gaaattgggaactattctttctacgccttggacaaccagaacctgaggcagctgtgggac tggaacaagcacaacctcacgatcactcagggcaagctcttcttccactacaaccccaaa ctctgcctgtctgagatccacaagatggaggaagtgtccggaaccaagggccgccaggag aggaacgacattgccctgaagaccaacggggaccaggcatcctgtgaaaatgaattactt aaattctctttcatccggacgtcttttgacaagatcttgctgaggtgggagccctactgg ccccccgacttccgagatctcctgggattcatgctgttctacaaagaggccccttatcag aacgtgacagagtttgacgggcaggatgcgtgtggctccaacagctggactgtggtggat attgacccgccccagaggtccaacgaccctaagtctcagaccccaagccaccctgggtgg ctgatgcggggcctcaaaccctggacccagtatgccatctttgtcaagaccttggttacc ttctctgatgaacgccggacctatggagccaaaagtgatatcatctatgtgcaaacagat gccaccaatccttccgttcccctggatcccatatcagtttccaactcctcatctcagatt atcttaaagtggaagcccccctcggaccccaatggcaacatcacacactacctggtctac tgggagaggcaggcggaggacagcgagctgttcgagttggattattgtctcaaagggctg aagctcccctcacgcacctggtccccaccttttgagtctgacgattctcaaaagcacaat cagagtgagtatgacgactcggccagcgagtgctgctcatgtcctaagactgactctcag atcctgaaggagctggaggagtcttcattcaggaagaccttcgaggattacctgcacaac gtggtttttgttcccagaaaaacctcttcaggcaatggtgctgaggacactaggccatcc cgaaagcgaagatcccttgaagaggtgggcaatgtgacagccactacacccacacttcca gattttcccaacatctcctccaccatcgcgcccacaagccacgaagagcacagaccattt gagaaagtagtaaacaaggagtcacttgtcatctctggcctgagacacttcactgggtac cgcattgagctgcaggcatgcaatcaggactccccagaagagaggtgcagcgtggctgcc tacgtcagtgcccggaccatgcctgaagctaaggcagatgacatcgttggccctgtgacc catgaaatctttgagaacaatgttgtacacttaatgtggcaagagccaaaggaacctaat ggtctgattgtgctatatgaagtgagctatcggcgatatggtgatgaggagctgcacctc tgtgtctcccggaagcattttgccctggagcggggctgcaggcttcgagggctctctcca ggaaactacagtgttcgagtccgggctacctctctggcaggaaatggctcctggacagaa cccacctatttttatgtgactgattatttagatgtcccatcaaatattgccaaaattatc atcgggcccctcatcttcgtcttcctcttcagtgtcgtgatcggaagtatttatctattc ttgaggaagaggcagccagatgggccaatgggaccactgtacgcttcttcaaacccagag tacctcagtgccagtgatgtctttccatcttccgtatacgttccggatgagtgggaggta cctcgagagaagatcaccctcctccgagagctggggcagggatccttcggtatggtgtac gaaggcaatgccaaggatatcatcaagggtgaggtagagacccgtgttgcggtgaagacg gtcaatgagtcagccagtcttcgagaacggatcgagttcctcaatgaggcatcagtcatg aagggcttcacctgtcatcacgtggtccgccttcttggggtggtgtccaaaggccagccc acattggtagtgatggaactgatggctcatggagacctgaaaagtcacctccgttctctg cggcccgatgctgagaacaacccaggccgtcctccccctaccttgcaagaaatgattcag atgacagcagaaattgccgatggcatggcatacttgaacgccaagaagtttgtgcaccgg gacctggcagctcggaactgcatggttgcccatgattttactgtcaaaatcggagacttt ggaatgacgagagacatctacgagacagattactatcggaaagggggcaaggggttgctg cccgtgaggtggatgtcacccgagtccctgaaggacggagtcttcactgcttcttccgac atgtggtcctttggggtggtcctttgggaaatcaccagcctggctgagcaaccttaccaa ggcctgtctaatgaacaggtgttgaaatttgtcatggatggaggctatctggatccccct gataactgtccagagagactcactgacctgatgcgcatgtgctggcagttcaaccccaag atgaggccgaccttcctggaaatcgtcaacctgctcaaggacgacctccaccccagcttt ccggaagtttccttcttctacagcgaggagaacaaggctcccgagagtgaagagctggag atggagttcgaggacatggagaatgtccccttggatcgttcctctcactgtcagagagaa gaggctggatgccgggagggagggtcctctctgagcatcaaacggacctatgatgaacac atcccctacacccacatgaacgggggcaagaagaatgggcgggtcctcaccctgccgagg tcgaacccttcctaa

DBGET integrated database retrieval system