Rattus norvegicus (rat): 25086 Help Entry 25086             CDS       T01003                                  Symbol Cyp2e1 Name (RefSeq) cytochrome P450 2E1   KO K07415   cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-] Organism rno  Rattus norvegicus (rat) Pathway rno00140   Steroid hormone biosynthesis rno00590   Arachidonic acid metabolism rno00591   Linoleic acid metabolism rno00980   Metabolism of xenobiotics by cytochrome P450 rno00982   Drug metabolism - cytochrome P450 rno00983   Drug metabolism - other enzymes rno01100   Metabolic pathways rno04932   Non-alcoholic fatty liver disease rno04936   Alcoholic liver disease rno05204   Chemical carcinogenesis - DNA adducts rno05208   Chemical carcinogenesis - reactive oxygen species Brite KEGG Orthology (KO) [BR:rno00001]  09100 Metabolism   09103 Lipid metabolism    00140 Steroid hormone biosynthesis     25086 (Cyp2e1)    00590 Arachidonic acid metabolism     25086 (Cyp2e1)    00591 Linoleic acid metabolism     25086 (Cyp2e1)   09111 Xenobiotics biodegradation and metabolism    00980 Metabolism of xenobiotics by cytochrome P450     25086 (Cyp2e1)    00982 Drug metabolism - cytochrome P450     25086 (Cyp2e1)    00983 Drug metabolism - other enzymes     25086 (Cyp2e1)  09160 Human Diseases   09161 Cancer: overview    05204 Chemical carcinogenesis - DNA adducts     25086 (Cyp2e1)    05208 Chemical carcinogenesis - reactive oxygen species     25086 (Cyp2e1)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     25086 (Cyp2e1)    04932 Non-alcoholic fatty liver disease     25086 (Cyp2e1)  09180 Brite Hierarchies   09181 Protein families: metabolism    00199 Cytochrome P450 [BR:rno00199]     25086 (Cyp2e1) Cytochrome P450 [BR:rno00199]  Cytochrome P450, animal type   CYP2 family    25086 (Cyp2e1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  p450 DUF6361 Sigma54_CBD Motif Other DBs NCBI-GeneID:  25086 NCBI-ProteinID:  NP_113731 RGD:  2475 Ensembl:  ENSRNOG00000012458 UniProt:  P05182 A6HXJ0 LinkDB All DBs Position 1:205269967..205280365 Genome browser AA seq 493 aa AA seqDB search MAVLGITIALLVWVATLLVISIWKQIYNSWNLPPGPFPLPILGNIFQLDLKDIPKSFTKL AKRFGPVFTLHLGSRRIVVLHGYKAVKEVLLNHKNEFSGRGDIPVFQEYKNKGIIFNNGP TWKDVRRFSLSILRDWGMGKQGNEARIQREAQFLVEELKKTKGQPFDPTFLIGCAPCNVI ADILFNKRFDYNDKKCLRLMSLFNENFYLLSTPWIQLYNNFADYLRYLPGSHRKIMKNVS EIKQYTLEKAKEHLQSLDINCARDVTDCLLIEMEKEKHSQEPMYTMENVSVTLADLFFAG TETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRVPAVRDRLDMPYMDAVVHEIQRF INLVPSNLPHEATRDTVFQGYVIPKGTVVIPTLDSLLYDSHEFPDPEKFKPEHFLNENGK FKYSDYFKAFSAGKRVCVGEGLARMELFLLLSAILQHFNLKSLVDPKDIDLSPVTVGFGS IPPQFKLCVIPRS NT seq 1482 nt NT seq  +upstreamnt  +downstreamnt atggcggttcttggcatcaccattgccttgctggtgtgggtggccaccctcctcgtcata tccatctggaagcagatctataacagttggaacctgcccccaggacctttccctcttccc atccttgggaacatttttcagctggatttgaaggatatccccaagtctttcaccaagttg gcaaagcgcttcgggccagtgttcacactgcaccttggctcaaggcgcatcgtggtcctg catggctacaaggctgtcaaggaggtgctactgaaccacaagaatgagttttctggacgg ggggacattcctgtgttccaggagtacaagaacaaggggattattttcaataatgggccc acatggaaggatgtgcggaggttttccctaagcattctccgagactggggaatggggaaa cagggtaatgaggcccgcatccaaagggaggcgcaattcctggtggaggagctcaaaaag accaaaggccagccttttgaccccacatttctgattggctgcgcaccctgcaatgtcatt gcggatatcctcttcaacaaacgtttcgactacaatgacaagaagtgtctgaggctcatg agtttgttcaatgaaaacttctacctgctgagcaccccctggatccagctttacaataac tttgcggattatctacgatacctacctggaagccatagaaaaatcatgaaaaatgtgtct gaaataaaacagtacacacttgaaaaagccaaggaacaccttcagtcactggacatcaac tgcgcccgggatgtgactgactgtctcctcatagagatggagaaggaaaaacacagccaa gaacccatgtacacaatggaaaatgtttctgtgactttggccgacctgttctttgcagga actgagaccaccagcacaactctgagatatgggctcctgatcctcatgaaatacccagaa attgaagagaaacttcatgaagaaattgacagggttattgggccaagccgcgtccctgct gtcagagacagactggatatgccctacatggatgctgtggtgcatgagatccagagattc atcaatcttgtcccttccaacctaccccatgaagcaaccagagatactgtgttccaagga tatgtcatccccaagggtacagttgtgattccaactctggactccctcttatatgacagc catgagtttccagatccagagaagtttaaacctgagcatttcctgaatgaaaatgggaag ttcaagtacagtgactatttcaaggcattttctgcaggaaagcgtgtgtgtgttggagaa ggcctggcccgcatggaattgtttctgctcctgtctgctattctgcagcattttaacctg aagtctctggttgaccctaaggatatcgacctcagtcctgtcacagttggctttggcagt atcccaccccaatttaaactctgtgtcattccccgttcatga

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