Rattus norvegicus (rat): 25166 Help Entry 25166             CDS       T01003                                  Symbol Casp1 Name (RefSeq) caspase-1   KO K01370   caspase 1 [EC:3.4.22.36] Organism rno  Rattus norvegicus (rat) Pathway rno04148   Efferocytosis rno04217   Necroptosis rno04613   Neutrophil extracellular trap formation rno04621   NOD-like receptor signaling pathway rno04623   Cytosolic DNA-sensing pathway rno04625   C-type lectin receptor signaling pathway rno05014   Amyotrophic lateral sclerosis rno05132   Salmonella infection rno05133   Pertussis rno05134   Legionellosis rno05135   Yersinia infection rno05164   Influenza A rno05171   Coronavirus disease - COVID-19 rno05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:rno00001]  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     25166 (Casp1)   09143 Cell growth and death    04217 Necroptosis     25166 (Casp1)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     25166 (Casp1)    04621 NOD-like receptor signaling pathway     25166 (Casp1)    04623 Cytosolic DNA-sensing pathway     25166 (Casp1)    04625 C-type lectin receptor signaling pathway     25166 (Casp1)  09160 Human Diseases   09172 Infectious disease: viral    05171 Coronavirus disease - COVID-19     25166 (Casp1)    05164 Influenza A     25166 (Casp1)   09171 Infectious disease: bacterial    05132 Salmonella infection     25166 (Casp1)    05135 Yersinia infection     25166 (Casp1)    05133 Pertussis     25166 (Casp1)    05134 Legionellosis     25166 (Casp1)   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     25166 (Casp1)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     25166 (Casp1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:rno01002]     25166 (Casp1)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:rno04131]     25166 (Casp1) Enzymes [BR:rno01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.36  caspase-1      25166 (Casp1) Peptidases and inhibitors [BR:rno01002]  Cysteine peptidases   Family C14: caspase family    25166 (Casp1) Membrane trafficking [BR:rno04131]  Autophagy   Other autophagy associated proteins    TRIM-directed selective autophagy     25166 (Casp1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 CARD Motif Other DBs NCBI-GeneID:  25166 NCBI-ProteinID:  NP_036894 RGD:  2274 Ensembl:  ENSRNOG00000007372 UniProt:  Q91W32 LinkDB All DBs Position 8:10746338..10882295 Genome browser AA seq 402 aa AA seqDB search MADKILRAKRKQFINSVSVGTINGLLDELLEKRVLNQEEMDTIKLANITVMEKARDLCDH VTKKGPRASQMFITYICNEDCYLAEILELQSGPSAETVFVTEDSKGGHPFSSETKEKLNK EGGAFPGPSGSLKFCPLEIAQKLWKENHSEIYPIMKTPTRTRLALIICNTDFQHLSRRVG ADVDLREMKLLLQDLGYTVKVKENLTALEMTKELKEFAACPEHKTSDSTFLVFMSHGLQE GICGITYSNEVADILKVDTIFQMMNTLKCPSLKDKPKVIIIQACRGEKQGVVLLKDSVGN SEEGFLTDAIFEDDGIKKAHIEKDFIAFCSSTPDNVSWRHPVQGSLFIESLIKHMKEYAW SCDLEDIFRKVRFSFEQPDSRLQMPTTERVTLTKRFYLFPGH NT seq 1209 nt NT seq  +upstreamnt  +downstreamnt atggctgacaagatcctgagggcaaagaggaagcaatttatcaactcagtgagtgtaggg acaataaatggattgctggatgaacttttagagaagagagtcctgaaccaggaagagatg gatacaatcaaacttgcaaatatcactgttatggaaaaggcacgagacctgtgcgatcat gtcactaaaaaaggaccccgggcaagccagatgtttatcacttacatttgtaatgaagac tgctacctggcagaaattctggagcttcagtcaggtccatcagctgaaactgtttttgtt acagaagattctaagggaggacatcctttctcctcagaaacaaaagaaaaactgaacaaa gaaggtggcgcatttcctggaccgagtggttccctcaagttttgccctttagaaatagcc cagaagttatggaaagaaaatcattcagagatttatccaataatgaaaacacccactcgt acacgtcttgccctcattatctgcaacacagactttcaacatctttctcggagagtcgga gctgatgttgacctcagagaaatgaagttgctgctgcaggatctggggtatactgtgaaa gtcaaagaaaatctcacagctctggagatgacaaaagaattgaaagaatttgctgcctgc ccagagcacaagacttctgacagtaccttccttgtattcatgtctcatggtctccaggag ggaatatgtgggatcacatactctaatgaagttgcagatattttaaaggttgacacaatc tttcaaatgatgaacacattgaagtgcccaagcttgaaagacaagcccaaggttatcatt attcaggcatgccgtggagagaaacaaggagtggtgttgttaaaagattcagtagggaac tccgaagagggattcttaacagatgcaatttttgaagatgatggcattaagaaggcccat atagagaaagattttattgctttctgctcttcaacaccagataatgtgtcctggagacat cctgtccagggatctctcttcattgagtcactcatcaaacacatgaaagaatatgcctgg tcttgtgacttggaggacattttcagaaaggttcgattttctttcgaacaaccagactct agactacagatgccaaccactgaaagggtgaccctgacaaaacgtttctacctcttccca ggacattaa

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