Rattus norvegicus (rat): 25313
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Entry
25313 CDS
T01003
Symbol
Egf
Name
(RefSeq) pro-epidermal growth factor precursor
KO
K04357
epidermal growth factor
Organism
rno
Rattus norvegicus (rat)
Pathway
rno01521
EGFR tyrosine kinase inhibitor resistance
rno04010
MAPK signaling pathway
rno04012
ErbB signaling pathway
rno04014
Ras signaling pathway
rno04015
Rap1 signaling pathway
rno04020
Calcium signaling pathway
rno04066
HIF-1 signaling pathway
rno04068
FoxO signaling pathway
rno04072
Phospholipase D signaling pathway
rno04151
PI3K-Akt signaling pathway
rno04510
Focal adhesion
rno04540
Gap junction
rno04630
JAK-STAT signaling pathway
rno04810
Regulation of actin cytoskeleton
rno05160
Hepatitis C
rno05165
Human papillomavirus infection
rno05200
Pathways in cancer
rno05207
Chemical carcinogenesis - receptor activation
rno05208
Chemical carcinogenesis - reactive oxygen species
rno05210
Colorectal cancer
rno05212
Pancreatic cancer
rno05213
Endometrial cancer
rno05214
Glioma
rno05215
Prostate cancer
rno05218
Melanoma
rno05219
Bladder cancer
rno05223
Non-small cell lung cancer
rno05224
Breast cancer
rno05226
Gastric cancer
rno05231
Choline metabolism in cancer
rno05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
25313 (Egf)
04012 ErbB signaling pathway
25313 (Egf)
04014 Ras signaling pathway
25313 (Egf)
04015 Rap1 signaling pathway
25313 (Egf)
04630 JAK-STAT signaling pathway
25313 (Egf)
04066 HIF-1 signaling pathway
25313 (Egf)
04068 FoxO signaling pathway
25313 (Egf)
04020 Calcium signaling pathway
25313 (Egf)
04072 Phospholipase D signaling pathway
25313 (Egf)
04151 PI3K-Akt signaling pathway
25313 (Egf)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
25313 (Egf)
04540 Gap junction
25313 (Egf)
09142 Cell motility
04810 Regulation of actin cytoskeleton
25313 (Egf)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
25313 (Egf)
05207 Chemical carcinogenesis - receptor activation
25313 (Egf)
05208 Chemical carcinogenesis - reactive oxygen species
25313 (Egf)
05231 Choline metabolism in cancer
25313 (Egf)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
25313 (Egf)
09162 Cancer: specific types
05210 Colorectal cancer
25313 (Egf)
05212 Pancreatic cancer
25313 (Egf)
05226 Gastric cancer
25313 (Egf)
05214 Glioma
25313 (Egf)
05218 Melanoma
25313 (Egf)
05219 Bladder cancer
25313 (Egf)
05215 Prostate cancer
25313 (Egf)
05213 Endometrial cancer
25313 (Egf)
05224 Breast cancer
25313 (Egf)
05223 Non-small cell lung cancer
25313 (Egf)
09172 Infectious disease: viral
05160 Hepatitis C
25313 (Egf)
05165 Human papillomavirus infection
25313 (Egf)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
25313 (Egf)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides [BR:
rno04052
]
25313 (Egf)
Cytokines and neuropeptides [BR:
rno04052
]
Cytokines
Growth factors (RTK binding)
25313 (Egf)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ldl_recept_b
FXa_inhibition
cEGF
EGF
EGF_CA
EGF_3
hEGF
Plasmod_Pvs28
DUF5050
Vgb_lyase
Tr-sialidase_C
LtrA
Motif
Other DBs
NCBI-GeneID:
25313
NCBI-ProteinID:
NP_036974
RGD:
2542
Ensembl:
ENSRNOG00000053979
UniProt:
P07522
A0A0G2KAF5
LinkDB
All DBs
Position
2:complement(220893660..220976331)
Genome browser
AA seq
1132 aa
AA seq
DB search
MLFSLTFLSVFLKITVLSVTAQQTRNCQSGPLERSGTSTYAAAGPPRFLIFLQGNSIFRI
NTDGTNHQQLVVDAGVSVVMDFHYKEERLYWVDLERQLLQRVFFNGSGQETVCKVDKNVS
GLAINWIDGEILRTDRWKGVITVTDMNGNNSRVLLSSLKRPANILVDPTERLIFWSSVVT
GNLHRADLGGMDVKTLLEAPERISVLILDILDKRLFWAQDGREGSHGYIHSCDYDGGSIH
HIRHQARHDLLTMAIFGDKILYSALKEKAIWIADKHTGKNVVRVNLDPASVPPRELRVVH
LHAQPGTENRAQASDSERCKQRRGQCLYSLSERDPNSDSCACAEGYTLSRDRKYCEDVNE
CALQNHGCTLGCENIPGSYYCTCPTGFVLLPDGKRCHELVACPGNRSECSHDCILTSDGP
LCICPAGSVLGKDGKTCTGCSSPDNGGCSQICLPLSLASWECDCFPGYDLQLDRKSCAAS
GPQPFLLFANSQDIRHMHFDGTDYKTLLSRQMGMVFALDYDPVESKIYFAQTALKWIERA
NLDGSQRERLITEGVDTPEGLAVDWIGRRIYWTDSGKSVIEGSDLSGKHHQIIIKESISR
PRGIAVHPKARRLFWTDTGMSPRIESSSLQGSDRTLIASSNLLEPSGIAIDYLTDTLYWC
DTKLSVIEMADLDGSKRRRLTQNDVGHPFSLAVFEDHVWFSDWAIPSVIRVNKRTGQNRV
RLRGSMLKPSSLVVVHPLAKPGADPCLHRNGGCEHICQESLGTAQCLCREGFVKAPDGKM
CLTRKDDQILAGDNADLSKEVASLDNSPKAYVPDDDRTESSTLVAEIMVSGLNYEDDCGP
GGCGSHAHCISEGEAAVCQCLKGFAGDGNLCSDIDECELGSSDCPPTSSRCINTEGGYVC
QCSEGYEGDGIYCLDVDECQQGSHGCSENATCTNTEGGYNCTCAGCPSAPGLPCPDSTSP
SLLGKDGCHWVRNSITGCPPSYDGYCLNGGVCMYVESVDRYVCNCVIGYIGERCQHRDLR
WWKLRHADYGQRHDITVVSVCVVALALLLLLGMWGTYYYRTRKQLSESSKKPSEESSSNV
SSNGPDSSGAGVSSGPQPWFVVLEEHQQPKNGRLPAAGTNGAVVEAGLSSSL
NT seq
3399 nt
NT seq
+upstream
nt +downstream
nt
atgctgttctcgctcaccttcctgtcggtgtttttaaagattactgtactcagtgtcaca
gcacagcagaccaggaactgtcagtcaggtcctctcgagagaagcgggacttccacgtat
gccgccgccggtcctcccaggttcctgattttcttacaaggaaacagcatctttcggatt
aacacagatggaacaaatcaccagcaattggtggtggatgccggcgtctcagtggtcatg
gattttcattacaaggaagagagactctattgggtggatttagaaagacaacttttgcaa
agagttttctttaatgggtcaggacaagagacagtgtgcaaggtggataagaatgtttct
gggctggccataaactggatagatggggagattctccggacggaccgatggaagggagtc
atcacagtaacagatatgaacgggaacaattcccgtgttcttctgagttccttaaaacgt
cctgcaaatatattagtggatccaacagagaggttgatattttggtcttcagtggtgact
ggcaaccttcacagagcagatctcgggggtatggatgtaaaaacactgctggaggcacca
gagaggatatcagtgctgattctggatatcctggacaaaaggctcttctgggctcaggac
ggtagagaaggaagccacggttacattcactcctgtgactatgacggtggctccatccat
catatcagacatcaagcacggcacgatttgcttactatggccattttcggtgacaagatc
ttatactcagcactgaaagagaaggcgatttggatagccgacaaacacactgggaagaat
gtggttcgagttaacctcgatccagcctctgtgccgccaagagaactgagagtcgtgcac
ctacatgcacagcccgggacagagaaccgtgctcaggcctctgactccgaacgatgcaaa
cagagaagaggacagtgtctctacagtctctctgagcgagaccccaactcagactcgtgc
gcatgcgctgaaggctatacgttaagccgagaccggaagtactgcgaagatgtcaatgag
tgtgccttgcagaatcacggctgtactcttgggtgtgaaaacatccctggatcctattac
tgcacatgccctacaggctttgttctgcttcctgatgggaaacgatgtcacgaacttgtt
gcctgtccaggcaacagatcagagtgtagccatgattgcatcctgacatcagatggtcct
ctgtgcatctgtccagcaggttcagtgctcggaaaagatgggaagacatgcactggttgt
tcatctcctgataatggtggatgcagccagatctgccttcctctcagcctagcatcctgg
gaatgtgattgctttcctgggtacgacctacaattggaccgaaagagctgtgcagcttca
ggaccgcagccatttttactgtttgcaaattcccaggacatacgacacatgcattttgat
ggaacagactacaaaactctgctcagccggcagatgggaatggtttttgccttggattat
gaccccgtggaaagcaagatatattttgcacagacagccctgaagtggatagagagggct
aatctggatggctcccagcgagaaagacttatcacggaaggagtagacacgccagaaggt
cttgccgtggactggattggccggagaatctactggacggacagtgggaagtccgtcatt
gaagggagtgatttgagcgggaagcatcatcaaataatcatcaaagagagcatctcaagg
ccacgaggaatagctgtgcatccaaaggccaggagactattctggacggacacggggatg
tctccgcggattgaaagctcttcccttcaaggttctgaccggacgctgatagccagctct
aatctactggaacccagtggaatcgcgattgactacttaacagacactttgtactggtgt
gacaccaagctgtctgtgattgaaatggccgatctagatggttccaaacgccgcagactt
acccagaacgatgtaggtcacccattctctctagctgtgtttgaggatcacgtgtggttc
tcggattgggctatcccatcggtaataagggtgaacaagaggactggtcaaaacagggta
cgtctccgaggcagcatgctgaagccctcgtcactggttgtggtccacccattggcaaaa
ccaggtgcagacccctgcttacacaggaatggaggctgtgaacacatctgccaagagagc
ctgggcacggctcagtgtctgtgtcgggaaggattcgtgaaggccccagatgggaaaatg
tgtctcactcggaaggatgatcagatactggccggtgacaatgctgatcttagtaaagag
gtagcatcgttggacaactcccctaaggcttatgtaccagacgatgacaggacagagtcc
tccacactagtggctgagatcatggtgtcagggctgaactatgaagatgactgcggccct
ggtgggtgtggcagccatgcccactgtatttcagagggagaggcagctgtgtgtcagtgt
ttgaaaggatttgctggcgatggaaacctgtgttctgatatagacgaatgtgagctgggt
agctcagactgtcctcccacctcgtccaggtgcatcaacaccgaaggtggctatgtctgc
caatgctcagaaggctacgagggagatgggatctactgtctcgacgttgatgagtgccag
caggggtcgcacggctgcagcgagaatgccacctgcaccaacacggagggaggctacaac
tgcacctgtgcaggctgcccatcagcacctggactgccttgccctgactctacctcaccc
tctctccttggaaaagatggctgccactgggtccgaaacagtatcacaggatgcccgccg
tcgtacgatgggtactgcctcaatggtggcgtgtgcatgtatgttgaatccgtggaccgc
tacgtgtgcaactgtgtcattggctatattggagaacgatgtcagcaccgagacttacgt
tggtggaagctgcgccatgctgactacgggcagaggcacgacatcactgtggtgtctgtc
tgtgtggtggcgctggccctgctgctcctcttagggatgtgggggacttactactacagg
actcggaagcagctatcagagagctcaaagaagccttccgaagagtcaagcagcaacgtg
agcagtaacgggcctgacagcagcggggctggggtgtcttctggtccccaaccttggttt
gtggtcctagaggaacaccaacagcccaagaatgggcgtctgcctgccgctggcacgaac
ggcgcagtagtagaggctggcctgtcttcctccctgtaa
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integrated database retrieval system
