KEGG   ORTHOLOGY: K04357
Entry
K04357                      KO                                     

Symbol
EGF
Name
epidermal growth factor
Pathway
map01521  EGFR tyrosine kinase inhibitor resistance
map04010  MAPK signaling pathway
map04012  ErbB signaling pathway
map04014  Ras signaling pathway
map04015  Rap1 signaling pathway
map04020  Calcium signaling pathway
map04066  HIF-1 signaling pathway
map04068  FoxO signaling pathway
map04072  Phospholipase D signaling pathway
map04151  PI3K-Akt signaling pathway
map04510  Focal adhesion
map04540  Gap junction
map04630  JAK-STAT signaling pathway
map04810  Regulation of actin cytoskeleton
map05160  Hepatitis C
map05165  Human papillomavirus infection
map05200  Pathways in cancer
map05207  Chemical carcinogenesis - receptor activation
map05208  Chemical carcinogenesis - reactive oxygen species
map05210  Colorectal cancer
map05212  Pancreatic cancer
map05213  Endometrial cancer
map05214  Glioma
map05215  Prostate cancer
map05218  Melanoma
map05219  Bladder cancer
map05223  Non-small cell lung cancer
map05224  Breast cancer
map05226  Gastric cancer
map05231  Choline metabolism in cancer
map05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Disease
H00020  Colorectal cancer
H01210  Hypomagnesemia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04357  EGF; epidermal growth factor
   04012 ErbB signaling pathway
    K04357  EGF; epidermal growth factor
   04014 Ras signaling pathway
    K04357  EGF; epidermal growth factor
   04015 Rap1 signaling pathway
    K04357  EGF; epidermal growth factor
   04630 JAK-STAT signaling pathway
    K04357  EGF; epidermal growth factor
   04066 HIF-1 signaling pathway
    K04357  EGF; epidermal growth factor
   04068 FoxO signaling pathway
    K04357  EGF; epidermal growth factor
   04020 Calcium signaling pathway
    K04357  EGF; epidermal growth factor
   04072 Phospholipase D signaling pathway
    K04357  EGF; epidermal growth factor
   04151 PI3K-Akt signaling pathway
    K04357  EGF; epidermal growth factor
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K04357  EGF; epidermal growth factor
   04540 Gap junction
    K04357  EGF; epidermal growth factor
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K04357  EGF; epidermal growth factor
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04357  EGF; epidermal growth factor
   05207 Chemical carcinogenesis - receptor activation
    K04357  EGF; epidermal growth factor
   05208 Chemical carcinogenesis - reactive oxygen species
    K04357  EGF; epidermal growth factor
   05231 Choline metabolism in cancer
    K04357  EGF; epidermal growth factor
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K04357  EGF; epidermal growth factor
  09162 Cancer: specific types
   05210 Colorectal cancer
    K04357  EGF; epidermal growth factor
   05212 Pancreatic cancer
    K04357  EGF; epidermal growth factor
   05226 Gastric cancer
    K04357  EGF; epidermal growth factor
   05214 Glioma
    K04357  EGF; epidermal growth factor
   05218 Melanoma
    K04357  EGF; epidermal growth factor
   05219 Bladder cancer
    K04357  EGF; epidermal growth factor
   05215 Prostate cancer
    K04357  EGF; epidermal growth factor
   05213 Endometrial cancer
    K04357  EGF; epidermal growth factor
   05224 Breast cancer
    K04357  EGF; epidermal growth factor
   05223 Non-small cell lung cancer
    K04357  EGF; epidermal growth factor
  09172 Infectious disease: viral
   05160 Hepatitis C
    K04357  EGF; epidermal growth factor
   05165 Human papillomavirus infection
    K04357  EGF; epidermal growth factor
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K04357  EGF; epidermal growth factor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K04357  EGF; epidermal growth factor
Cytokines and growth factors [BR:ko04052]
 Growth factors
  Growth factors (RTK binding)
   K04357  EGF; epidermal growth factor
Other DBs
GO: 0005155
Genes
HSA: 1950(EGF)
PTR: 461435(EGF)
PPS: 100975632(EGF)
GGO: 101153700(EGF)
PON: 100455021(EGF)
NLE: 100588963(EGF)
MCC: 698619(EGF)
MCF: 102123415(EGF)
CSAB: 103236114(EGF)
CATY: 105571434(EGF)
PANU: 101026665(EGF)
RRO: 104682421(EGF)
RBB: 108541026(EGF)
TFN: 117085785(EGF)
PTEH: 111547933(EGF)
CJC: 100388651(EGF)
SBQ: 101052478(EGF)
MMUR: 105872305(EGF)
MMU: 13645(Egf)
MCAL: 110291005(Egf)
MPAH: 110320006(Egf)
RNO: 25313(Egf)
MCOC: 116093773(Egf)
MUN: 110553196(Egf)
CGE: 100763146(Egf)
PLEU: 114682692(Egf)
NGI: 103742642(Egf)
HGL: 106007527(Egf)
CCAN: 109700925(Egf)
OCU: 100008808(EGF)
TUP: 102490423(EGF)
CFA: 403657(EGF)
VVP: 112934223(EGF)
VLG: 121492863(EGF)
AML: 100467733
UMR: 103661742(EGF)
UAH: 113255562(EGF)
ORO: 101377629(EGF)
ELK: 111156359
MPUF: 101682951(EGF)
EJU: 114222658(EGF)
MLX: 118027092(EGF)
FCA: 493978(EGF)
PTG: 102959656(EGF)
PPAD: 109248153(EGF)
AJU: 106983657(EGF)
HHV: 120236138(EGF)
BTA: 530315(EGF)
BOM: 102285914(EGF)
BIU: 109559983(EGF)
BBUB: 102416325(EGF)
CHX: 106502173(EGF)
ODA: 120862277(EGF)
SSC: 397083(EGF)
CFR: 102523769(EGF)
CBAI: 105067960(EGF)
CDK: 105089905(EGF)
BACU: 103004366(EGF)
LVE: 103073883(EGF)
OOR: 101283152(EGF)
DLE: 111186135(EGF)
PCAD: 102977431(EGF)
ECB: 106782874(EGF)
EPZ: 103543333
EAI: 106829795(EGF)
MYB: 102264252(EGF)
MYD: 102758044(EGF)
MMYO: 118672981(EGF)
MNA: 107534373(EGF)
HAI: 109379436(EGF)
DRO: 112296254(EGF)
SHON: 118977074(EGF)
AJM: 119057431(EGF)
MMF: 118634494(EGF)
PALE: 102891552(EGF)
PGIG: 120591156(EGF)
RAY: 107508819(EGF)
MJV: 108408073(EGF)
TOD: 119243624(EGF)
LAV: 100670137(EGF)
TMU: 101355971
MDO: 100619143(EGF)
SHR: 100933169(EGF)
PCW: 110218605(EGF)
OAA: 100074960(EGF)
GGA: 408035(EGF)
PCOC: 116231267(EGF)
MGP: 100543460(EGF)
CJO: 107313609(EGF)
NMEL: 110399042(EGF)
APLA: 101795002(EGF)
ACYG: 106038683(EGF)
TGU: 100218747(EGF)
LSR: 110467994(EGF)
SCAN: 103826255(EGF)
PMOA: 120502809(EGF)
GFR: 102034269(EGF)
FAB: 101819290(EGF)
PHI: 102112980(EGF)
PMAJ: 107203603(EGF)
CCAE: 111927782(EGF)
CCW: 104697130(EGF)
ETL: 114062174(EGF)
FPG: 101916879(EGF)
FCH: 102049265(EGF)
CLV: 102083886(EGF)
EGZ: 104135535(EGF)
NNI: 104021157(EGF)
ACUN: 113479739(EGF)
PADL: 103926035(EGF)
AAM: 106491937(EGF)
ASN: 102388605(EGF)
AMJ: 102560233(EGF)
CPOO: 109309386(EGF)
GGN: 109301074(EGF)
PSS: 102453328(EGF)
CMY: 102933086(EGF)
CPIC: 101934754(EGF)
TST: 117877887(EGF)
CABI: 116827248(EGF)
ACS: 100562822(egf)
PVT: 110087292(EGF)
PBI: 103061516(EGF)
PMUR: 107290128(EGF)
PGUT: 117679942(EGF)
PMUA: 114604055(EGF)
ZVI: 118083713(EGF)
GJA: 107122699(EGF)
XLA: 108710179(egf.L)
XTR: 100127663(egf)
NPR: 108798307(EGF)
DRE: 403045(egf)
CAUA: 113114148
IPU: 108268549(egf)
PHYP: 113547167
AMEX: 103045727(egf)
EEE: 113579942(egf)
TRU: 101061284(egf)
LCO: 104917921(egf)
NCC: 104953729(egf)
CGOB: 115014303(egf)
ELY: 117260540(egf)
PLEP: 121947780(egf)
SLUC: 116052916(egf)
ECRA: 117951707(egf)
PFLV: 114563345(egf)
GAT: 120818259(egf)
MSAM: 119888559(egf)
CUD: 121516668(egf)
MZE: 101487082(egf)
ONL: 100706539(egf)
OAU: 116335758(egf)
OLA: 101167023(egf)
OML: 112141457(egf)
XMA: 102219388(egf)
XCO: 114138665(egf)
XHE: 116714467(egf)
PRET: 103471828(egf)
CVG: 107095811(egf)
CTUL: 119772614(egf)
NFU: 107374766(egf)
KMR: 108236662(egf)
ALIM: 106513245
AOCE: 111588376(egf)
CSEM: 103390644(egf)
POV: 109625474(egf)
LCF: 108885177(egf)
SDU: 111232468(egf)
SLAL: 111648180(egf)
XGL: 120785682(egf)
HCQ: 109524192(egf)
BPEC: 110153711(egf)
MALB: 109964289
SASA: 106611584(egf)
OTW: 112256330(egf)
OMY: 110505117(egf)
SALP: 111968192(egf)
SNH: 120061877
ELS: 105027559(egf)
SFM: 108938717(egf)
PKI: 111849374(egf)
LOC: 102689722(egf)
LCM: 102348800 102356822(EGF)
CMK: 103180890(egf)
RTP: 109929559(egf)
SKO: 102807105
ADF: 107331023
 » show all
Reference
PMID:3491360
  Authors
Bell GI, Fong NM, Stempien MM, Wormsted MA, Caput D, Ku LL, Urdea MS, Rall LB, Sanchez-Pescador R
  Title
Human epidermal growth factor precursor: cDNA sequence, expression in vitro and gene organization.
  Journal
Nucleic Acids Res 14:8427-46 (1986)
DOI:10.1093/nar/14.21.8427
  Sequence
[hsa:1950]
Reference
  Authors
Hermann PM, van Kesteren RE, Wildering WC, Painter SD, Reno JM, Smith JS, Kumar SB, Geraerts WP, Ericsson LH, Smit AB, Bulloch AG, Nagle GT
  Title
Neurotrophic actions of a novel molluscan epidermal growth factor.
  Journal
J Neurosci 20:6355-64 (2000)
DOI:10.1523/JNEUROSCI.20-17-06355.2000
  Sequence
[mmu:13645]
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