Rattus norvegicus (rat): 291450
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Entry
291450 CDS
T01003
Symbol
Aldh7a1
Name
(RefSeq) alpha-aminoadipic semialdehyde dehydrogenase
KO
K14085
aldehyde dehydrogenase family 7 member A1 [EC:
1.2.1.31
1.2.1.8
1.2.1.3
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00010
Glycolysis / Gluconeogenesis
rno00053
Ascorbate and aldarate metabolism
rno00071
Fatty acid degradation
rno00260
Glycine, serine and threonine metabolism
rno00280
Valine, leucine and isoleucine degradation
rno00310
Lysine degradation
rno00330
Arginine and proline metabolism
rno00340
Histidine metabolism
rno00380
Tryptophan metabolism
rno00410
beta-Alanine metabolism
rno00561
Glycerolipid metabolism
rno00620
Pyruvate metabolism
rno00670
One carbon pool by folate
rno01100
Metabolic pathways
rno04936
Alcoholic liver disease
Module
rno_M00032
Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
rno_M00135
GABA biosynthesis, eukaryotes, putrescine => GABA
rno_M00555
Betaine biosynthesis, choline => betaine
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
291450 (Aldh7a1)
00053 Ascorbate and aldarate metabolism
291450 (Aldh7a1)
00620 Pyruvate metabolism
291450 (Aldh7a1)
09103 Lipid metabolism
00071 Fatty acid degradation
291450 (Aldh7a1)
00561 Glycerolipid metabolism
291450 (Aldh7a1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
291450 (Aldh7a1)
00280 Valine, leucine and isoleucine degradation
291450 (Aldh7a1)
00310 Lysine degradation
291450 (Aldh7a1)
00330 Arginine and proline metabolism
291450 (Aldh7a1)
00340 Histidine metabolism
291450 (Aldh7a1)
00380 Tryptophan metabolism
291450 (Aldh7a1)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
291450 (Aldh7a1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
291450 (Aldh7a1)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
291450 (Aldh7a1)
Enzymes [BR:
rno01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.3 aldehyde dehydrogenase (NAD+)
291450 (Aldh7a1)
1.2.1.8 betaine-aldehyde dehydrogenase
291450 (Aldh7a1)
1.2.1.31 L-aminoadipate-semialdehyde dehydrogenase
291450 (Aldh7a1)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Aldedh
DUF1487
Motif
Other DBs
NCBI-GeneID:
291450
NCBI-ProteinID:
NP_001258034
RGD:
1308614
Ensembl:
ENSRNOG00000014645
UniProt:
Q64057
A6IX60
LinkDB
All DBs
Position
18:complement(52208035..52240293)
Genome browser
AA seq
539 aa
AA seq
DB search
MLRLARPLCVQTVKASKLSRLWSRPAALMSTLLIHHPQYAWLQDLGLREDNEGVFNGSWG
GRGEVITTYCPANNEPIARVRQASMKDYEETIGKAKKAWNIWADIPAPKRGEIVRKIGDA
LREKIQLLGRLVSLEMGKILVEGIGEVQEYVDVCDYAAGLSRMIGGPTLPSERPGHALME
QWNPLGLVGIITAFNFPVAVFGWNNAIALITGNVCLWKGAPTTSLVSIAVTKIIAKVLED
NLLPGAICSLTCGGADMGTAMARDERVNLLSFTGSTQVGKQVALMVQERFGKSLLELGGN
NAIIAFEDADLSLVLPSALFAAVGTAGQRCTTVRRLFLHESIHDEVVDRLKNAYSQIRVG
NPWDPNILYGPLHTKQAVSMFVQAVEEAKKEGGTVVYGGKVMDHPGNYVEPTIVTGLVHD
APIVHKETFAPILYVFKFKNEEEVFEWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGI
VNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSTALPLAQGIKFQ
NT seq
1620 nt
NT seq
+upstream
nt +downstream
nt
atgttgcgtctggctcgcccgctctgcgtgcagactgtgaaggccagcaaactttcccgc
ctttggagtaggcctgccgcccttatgtctactctgctgatccatcatccccagtatgcc
tggctgcaagacctgggtctccgcgaagataacgagggcgtgtttaatggaagctggggc
ggccggggagaggtaattacgacctattgtcctgctaacaatgagccaatagcaagagtc
cgacaggccagcatgaaagactatgaagagactatagggaaagccaagaaagcttggaac
atctgggcagatattcctgccccaaagcgaggagaaatagtcagaaagattggcgatgcc
ttgcgggagaagatccaattactgggaagactggtgtctttggagatggggaaaatctta
gtggaaggaataggggaggttcaggagtacgtggacgtctgcgattatgctgccggcttg
tcgaggatgatcgggggacccaccttgccctctgaaagacccggccatgctctcatggaa
cagtggaatccgttaggcctggtgggaatcatcactgccttcaacttccctgtggctgtg
tttggctggaacaatgccatagctctgatcacaggcaacgtctgcctttggaaaggagca
ccaacaacttccctcgttagtatagctgtcacaaagatcatagccaaggttttggaggac
aacctgctgcctggtgccatttgctccctgacctgtggtggagcagatatgggcacagca
atggccagagatgagcgtgtgaacctgctgtcgttcactgggagcactcaggtggggaag
caggtggccctcatggtgcaggagaggtttgggaaaagcttgttggagctcggaggaaac
aatgccatcattgctttcgaggacgccgacctcagcttggttcttccctccgctctgttt
gccgccgtgggaacagccggccagaggtgtaccactgtgaggcgactgtttttgcacgaa
agcatccatgatgaagttgtagacagactgaaaaatgcctactcacagatccgtgtcggg
aacccctgggaccccaatatcctctatggaccgctccacaccaaacaggcggtgagcatg
tttgtgcaagccgtggaagaagcaaagaaagaaggaggcacggtggtctatgggggcaag
gtcatggaccaccctggcaattatgtggaacccaccattgtgactggtcttgtccatgat
gcgcccattgttcacaaggagacttttgccccaattctctatgtcttcaaattcaagaat
gaagaagaggtctttgaatggaacaatgaagtaaaacagggactttcgagtagtatcttt
accaaggatctgggcagaatcttccgctggcttggacctaagggttcagactgtggcatt
gtgaacgtcaatattcctaccagcggggctgagatcggcggtgcgtttggaggcgagaag
cacacgggcggtggcagggaatctggcagcgatgcctggaagcagtacatgcggagatct
acgtgtaccatcaactacagcacggccctccctctggctcaaggtatcaagtttcagtga
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