KEGG   Rattus norvegicus (rat): 301595
Entry
301595            CDS       T01003                                 
Symbol
Ugt1a8
Name
(RefSeq) UDP-glucuronosyltransferase 1A8 precursor
  KO
K00699  glucuronosyltransferase [EC:2.4.1.17]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00040  Pentose and glucuronate interconversions
rno00053  Ascorbate and aldarate metabolism
rno00140  Steroid hormone biosynthesis
rno00830  Retinol metabolism
rno00860  Porphyrin metabolism
rno00980  Metabolism of xenobiotics by cytochrome P450
rno00982  Drug metabolism - cytochrome P450
rno00983  Drug metabolism - other enzymes
rno01100  Metabolic pathways
rno01240  Biosynthesis of cofactors
rno04976  Bile secretion
rno05204  Chemical carcinogenesis - DNA adducts
rno05207  Chemical carcinogenesis - receptor activation
Module
rno_M00014  Glucuronate pathway (uronate pathway)
rno_M00129  Ascorbate biosynthesis, animals, glucose-1P => ascorbate
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    301595 (Ugt1a8)
   00053 Ascorbate and aldarate metabolism
    301595 (Ugt1a8)
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    301595 (Ugt1a8)
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    301595 (Ugt1a8)
   00860 Porphyrin metabolism
    301595 (Ugt1a8)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    301595 (Ugt1a8)
   00982 Drug metabolism - cytochrome P450
    301595 (Ugt1a8)
   00983 Drug metabolism - other enzymes
    301595 (Ugt1a8)
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    301595 (Ugt1a8)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    301595 (Ugt1a8)
   05207 Chemical carcinogenesis - receptor activation
    301595 (Ugt1a8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:rno01003]
    301595 (Ugt1a8)
Enzymes [BR:rno01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.17  glucuronosyltransferase
     301595 (Ugt1a8)
Glycosyltransferases [BR:rno01003]
 Others
  Hydrophobic molecule
   301595 (Ugt1a8)
SSDB
Motif
Pfam: UDPGT EryCIII-like_C Glyco_tran_28_C AMPK1_CBM OYE-like_second_a-b Pox_A14
Other DBs
NCBI-GeneID: 301595
NCBI-ProteinID: NP_787040
RGD: 708474
Ensembl: ENSRNOG00000018740
UniProt: A6JQH6 M0RB50
LinkDB
Position
9:96174899..96256264
AA seq 530 aa
MAPSGCPPSLPLCVCLFLASGFAQAGRLLVVPMDGSHWFTMQMIVEKLSHRGHEVVVVIP
EVSWHMGKSLNFTVKTYSVSYTLEDLNYHFKFFAHNQWKTQEVGMFSLLKHSGKGFFELL
FSHCRSLFKDKKLVEYLKQSSFDAVFLDPFDVCGLILAKYFSLPSVVFSGGIFCHYLDEG
AQCPSPPSYVPRILSKFTDTMTFKERVWNHLSYMKERAFCPYFFKTAVEIASEVLQTPVT
MRDLFSPVSIWMFRTDFVLEFPRPVMPNMVYIGGINCHQGKPLSKEFEAYVNASGEHGIV
VFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGH
PKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDL
ENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTW
YQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH
NT seq 1593 nt   +upstreamnt  +downstreamnt
atggctccttcaggctgtccaccctcccttcctctgtgtgtttgtctgttcctggcctct
ggctttgcccaggcaggcaggctgctggtagtgcccatggacgggagccactggttcacc
atgcagatgattgtggagaaactgagtcacagagggcatgaggtggtggtagtcatccca
gaggtgagttggcacatgggaaagtcgctgaattttaccgtgaaaacttactcagtttct
tacactctggaagatttaaactaccacttcaagttttttgctcacaaccaatggaaaact
caagaagtagggatgttttctctactgaagcattcaggcaaaggtttcttcgaattactg
ttttcacactgtaggagtttgtttaaggacaagaagttagtggagtacttgaagcagagt
tcgtttgatgctgtgtttctggatccttttgatgtgtgtggcttaattcttgccaagtac
ttttctctcccgtccgtggtcttcagcgggggaatattttgccactaccttgatgagggt
gcccagtgccccagtcctccttcttatgttcccagaattctctcaaaattcacagacacc
atgactttcaaggagagagtgtggaaccatctctcctacatgaaggagcgtgcattttgc
ccctactttttcaaaactgccgtagaaattgcctctgaagttctccagaccccggtgact
atgagagacctcttcagcccagtgtccatttggatgtttcgaactgactttgtgctggag
ttccccagacctgtgatgcccaacatggtctacattggtgggatcaactgccaccagggg
aagccactttccaaggaatttgaagcctatgtcaacgcctccggagaacatggcatcgtg
gttttctctttgggatccatggtctcagagattccagagaagaaagcgatggaaattgct
gaggctttgggcagaattcctcagacggtcctgtggcgctacaccggaactagaccatcg
aaccttgcaaagaacactattcttgtcaaatggctaccccaaaacgatctgcttggtcat
ccaaaggctcgggcgttcatcacacactccggttcccatggtatttatgaaggaatatgc
aatggggttccaatggtgatgatgcccttgtttggtgatcagatggacaacgccaagcgc
atggaaactcggggagctggggtgaccctgaatgtcctggaaatgactgccgatgatttg
gaaaacgcccttaaaactgtcatcaataacaagagttacaaggagaacatcatgcgcctc
tccagccttcacaaggaccgtcctatcgagcctctggacctggctgtgttctgggtggag
tacgtgatgaggcacaagggggcgccacacctgcgccccgccgcccacgacctcacctgg
taccagtaccactccttggacgtgattggctttctcctggccatcgtgttgacggtggtc
ttcattgtctataaaagttgtgcctatggctgccggaaatgctttgggggaaagggtcga
gtgaagaaatcacacaaatccaagacccactga

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