Rattus norvegicus (rat): 309262
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Entry
309262 CDS
T01003
Symbol
Nsdhl
Name
(RefSeq) sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating
KO
K07748
sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating) [EC:
1.1.1.170
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00100
Steroid biosynthesis
rno01100
Metabolic pathways
Module
rno_M00101
Cholesterol biosynthesis, FPP => cholesterol
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09103 Lipid metabolism
00100 Steroid biosynthesis
309262 (Nsdhl)
Enzymes [BR:
rno01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.170 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
309262 (Nsdhl)
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Gene cluster
GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
GDP_Man_Dehyd
NAD_binding_10
RmlD_sub_bind
NAD_binding_4
Polysacc_synt_2
NmrA
NAD_binding_2
3HCDH_N
Motif
Other DBs
NCBI-GeneID:
309262
NCBI-ProteinID:
NP_001009399
RGD:
1359337
Ensembl:
ENSRNOG00000057814
UniProt:
Q5PPL3
A6KSY6
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All DBs
Position
X:155817301..155848224
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AA seq
362 aa
AA seq
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MEQAVRSESKKGQVTGTDLINEVSKAKKCTVIGGSGFLGQHMVEQLLSRGYAVNVFDVRQ
GFDNPRVQFFIGDLCNQQDLYPALKGVSTVFHCASPPSNSNNKELFYRVNSTGTKTVIET
CKEAGVQKLILTSSASVVFEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLDANDPKK
NFLTAAIRPHGIFGPRDPQLVPVLIDAARKGKMKFMIGNGKNLVDFTFVENVVHGHILAA
EHLSRDAGLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYRVAYYLAFLLSLLV
MVLSPLIQIQTTFTPFRVALAGTFHYYSCEKAKKLIGYRPLVTMDDAVERTVQSFHHLRK
DK
NT seq
1089 nt
NT seq
+upstream
nt +downstream
nt
atggaacaggctgttcgtagtgaatcaaagaaaggccaggtcacagggacagatttgata
aatgaagtttccaaagctaagaagtgcacagtgattggaggctctgggttcctggggcag
cacatggtagagcagttgctatcgcgaggctatgctgtcaatgtatttgatgtccgccaa
ggctttgataaccctcgggtgcagttcttcataggtgacctgtgcaaccaacaggacctg
tacccagctctcaaaggtgtaagcacagttttccactgtgcgtcacccccgtcaaacagt
aacaacaaggagctcttttatagagtgaattccactggcaccaagactgtcattgaaacc
tgcaaagaggctggagttcagaaactcattttaaccagctctgccagtgttgtctttgag
ggtgtcgatataaaaaatggaactgaagacctcccttatgccatgaagcccattgactac
tatacagagaccaagatcttgcaggaaagagcagtactggatgccaacgaccctaagaag
aattttttaactgcagccattcgtcctcatggcatatttggcccaagagatccccagttg
gtcccagtcttaattgatgcagctagaaaaggcaaaatgaagttcatgattggaaatggg
aagaacctggtggacttcaccttcgtggagaatgtagttcatggacacatcttagcagct
gagcacctctctcgagatgcaggtctgggtgggaaggcatttcacatcaccaacgatgag
ccaatccctttctggacgttcctgtcccgcattctgacaggcctcaattatgaggccccc
aagtaccacatcccctacagggtggcctactatcttgctttcctgctatctctactggta
atggtgctcagccctctcatccaaatccagacaacttttacaccatttcgggtggcactg
gctggaacattccactattacagttgtgagaaagccaaaaagctcattgggtaccggcca
ctggtcaccatggatgatgctgtggaaaggactgtgcagagtttccaccacctgcggaag
gacaagtga
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