Rattus norvegicus (rat): 311567
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Entry
311567 CDS
T01003
Symbol
Itch
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04120
Ubiquitin mediated proteolysis
rno04144
Endocytosis
rno04330
Notch signaling pathway
rno04668
TNF signaling pathway
rno04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
311567 (Itch)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
311567 (Itch)
04668 TNF signaling pathway
311567 (Itch)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
311567 (Itch)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
311567 (Itch)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
rno04131
]
311567 (Itch)
04121 Ubiquitin system [BR:
rno04121
]
311567 (Itch)
Enzymes [BR:
rno01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
311567 (Itch)
Membrane trafficking [BR:
rno04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
311567 (Itch)
Ubiquitin system [BR:
rno04121
]
Ubiquitin ligases (E3)
HECT type E3
311567 (Itch)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
311567
NCBI-ProteinID:
NP_001005887
RGD:
1359556
Ensembl:
ENSRNOG00000059043
UniProt:
A0A0G2K9T1
A6KI19
Q5YB86
LinkDB
All DBs
Position
3:164102490..164193932
Genome browser
AA seq
864 aa
AA seq
DB search
MSDSAPQLDSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPMSKLCFRVWSHQTLKSDVLLGTAGLDIYETLKSNNMKLEEVVMTL
QLVGDKEPTETMGDLSVCLDGLQVEAEVVTNGETSCSEGATQNDAGCRPKDETRVSTNGS
EDPEVAASGENKRANGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSTNSDSD
GSSTGSLPPTNTNVNSSASEGAASGLIIPLTISGGSGPRPLNTVSQAPLPPGWEQRVDQH
GRVYYVDHVEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQ
WQLQRSQLQGAMQQFNQRFIFGNQDLFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNH
NTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRATTYIDPRTGKSALDNG
PQIAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWV
IFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFR
FIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEEC
GLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFE
GFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIVWFWQFVKEI
DNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPP
YKSYEQLKEKLLFAIEETEGFGQE
NT seq
2595 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtgcaccacagctcgattcaatgggtagcctgaccatgaaatctcaactt
cagattactgtcatctcagccaaacttaaagaaaataaaaagaattggtttggaccaagt
ccttatgtagaagtcacagtagatgggcagtcaaagaagacagaaaaatgcaacaataca
aacagccccaagtggaagcagcccctcacagttatcgttacccctatgagtaaattatgt
tttcgtgtgtggagtcaccagaccctgaaatctgatgttttattgggaactgctggatta
gatatttatgaaacattaaagtcaaacaatatgaaacttgaggaagtagttatgactttg
cagcttgtaggtgacaaagagccaacagagacaatgggagatttgtcagtttgtcttgat
gggctgcaagtagaagctgaagttgttactaatggtgaaacttcatgctcagagggtgct
acacagaatgacgctggctgcagacccaaagatgaaacaagagtgagcacaaatggatca
gaggaccctgaggttgcagcctcgggggaaaacaagagggccaatgggaacaattctcca
tccctttcaaatggtggttttaagccttctagacctcctagaccttcaagaccacctcca
cccaccccacgaagaccagcttctgtcaatggctcaccatccacgaactctgacagcgat
ggatctagcacaggctctttgccacccacaaatacaaatgtaaattcaagtgcatcggaa
ggagcagcatctgggttaataattcctctgaccatctctgggggctcaggccctaggccg
ctgaatactgtcagtcaagctcccctcccacctgggtgggagcagagagtagatcagcat
gggcgtgtttactatgtagaccatgttgaaaagcgaacaacatgggatagaccggaacct
ctacctcctggctgggaacggcgtgtggacaatatgggacgtatttattatgttgaccat
ttcacgagaaccacaacatggcagaggccgaccttggaatctgtccggaactatgagcag
tggcagctccagcgtagtcaacttcagggagcaatgcagcagtttaaccagagattcatc
tttgggaatcaagatttgtttgctacatcacaaaacaaagagtttgatccccttggtcct
ttgccccctggatgggagaagagaactgatagcaacggcagagtgtattttgtcaaccac
aacactcggattacacagtgggaagaccccagaagccaaggtcagttaaatgaaaagccc
ttaccagaaggctgggaaatgcgattcacagtggatggaattccatattttgtggaccac
aatagaagagcaactacctacatagatccacgcacaggaaagtcagccttagacaacgga
ccccagatagcctatgttcgggacttcaaggcaaaagttcagtatttccggttctggtgt
cagcaactggccatgccacagcatataaagatcacagtgacaagaaaaacattgtttgag
gattcctttcaacagatcatgagcttcagtccgcaagatctgagaagacgtttgtgggtg
attttcccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttctt
ttgtcacatgaagtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataac
tactgcctgcagataaaccccgcttcttatatcaacccagaccacctgaaatacttccgt
tttattggcagatttattgccatggctctattccatgggaaattcatagataccggattt
tctttaccattctataaacgtatcttgaataaaccagtgggacttaaggatttagaatct
atcgatccagaattttacaattctctcatctgggttaaagaaaacaatatcgaggaatgt
ggtttggaaatgtacttctcagttgataaagaaattctgggtgaaattaagagtcatgat
ttgaaacccaatggtggcaatattctggtgacagaagaaaataaggaagagtacatcagg
atggtcgctgagtggaggttgtctcggggagttgaagagcagacacaagctttctttgag
ggctttaatgaaattcttcctcagcaatatttgcaatattttgatgcgaaggaattagag
gtccttttgtgtgggatgcaggagatcgatttgaatgactggcagagacacgccatctac
cgtcactataccaggacgagcaagcagatcgtgtggttttggcagtttgttaaagaaatt
gataacgagaagaggatgcgacttctgcagtttgttaccggaacctgccgattgccagtg
ggaggatttgctgacctcatggggagtaatggaccacagaagttctgcatcgaaaaagtt
ggcaaagaaaattggttacccagaagccatacttgttttaaccgcctggacctcccaccc
tacaagagctatgagcaactgaaggaaaagctgttatttgccattgaagaaacagaagga
tttggacaagagtaa
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