Rattus norvegicus (rat): 312299
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Entry
312299 CDS
T01003
Symbol
Ezh2
Name
(RefSeq) histone-lysine N-methyltransferase EZH2
KO
K11430
[histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:
2.1.1.356
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00310
Lysine degradation
rno01100
Metabolic pathways
rno03083
Polycomb repressive complex
rno05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
312299 (Ezh2)
09120 Genetic Information Processing
09126 Chromosome
03083 Polycomb repressive complex
312299 (Ezh2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
312299 (Ezh2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
rno03036
]
312299 (Ezh2)
Enzymes [BR:
rno01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.356 [histone H3]-lysine27 N-trimethyltransferase
312299 (Ezh2)
Chromosome and associated proteins [BR:
rno03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
312299 (Ezh2)
Polycomb repressive complex (PRC) and associated proteins
PRC2.1
312299 (Ezh2)
PRC2.2
312299 (Ezh2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ezh2_MCSS
PRC2_HTH_1
SET
EZH2_WD-Binding
preSET_CXC
Motif
Other DBs
NCBI-GeneID:
312299
NCBI-ProteinID:
NP_001128451
RGD:
1595860
Ensembl:
ENSRNOG00000006048
UniProt:
F7F5Z0
B5DFE2
LinkDB
All DBs
Position
4:complement(77624223..77698598)
Genome browser
AA seq
746 aa
AA seq
DB search
MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKTMFSSNRQKILERTETLNQEW
KQRRIQPVHIMTSVSSLRGTRECSVTSDLDFPAQVIPLKTLNAVASVPIMYSWSPLQQNF
MVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQ
YNDDDDDDDGDDPDEREEKQKDLDDSRDDKETCPPRKFPADKIFEAISSMFPDKGTAEEL
KEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFH
ATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRRGRLPN
NSSRPSTPTISVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQTPIKM
KPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPV
PTEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVIAQ
NFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVS
CKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDK
YMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGE
ELFFDYRYSQADALKYVGIEREMEIP
NT seq
2241 nt
NT seq
+upstream
nt +downstream
nt
atgggccagactgggaagaaatctgagaagggaccggtttgttggcggaagcgtgtaaag
tcagagtacatgagactgagacagctcaagaggttcagaagagctgacgaagtaaagact
atgtttagttccaatcgtcagaaaattttggaaagaactgaaaccttaaatcaagaatgg
aagcagcgaaggatacagcctgtgcacatcatgacttctgtgagctcattacgcgggact
agggagtgttcagtgaccagtgacttggattttccagcacaagtcatcccgttaaagacc
ctaaatgctgtcgcatcggtgcccataatgtattcttggtctcccttacaacagaatttt
atggtggaagatgaaactgttttacataacattccttatatgggggatgaagttctggat
caggatggcactttcattgaagaattaataaaaaattatgatggaaaagtgcatggagac
agagaatgtggatttataaatgatgaaatttttgtggagttggtaaatgctcttggtcaa
tataatgatgatgacgatgatgatgatggagacgatcctgatgaaagagaagaaaaacag
aaagatctagacgatagtcgagatgataaagaaacttgcccacctcggaaatttcctgct
gataaaatatttgaagccatttcctcaatgtttccagataagggcacagcagaagaactg
aaagaaaagtataaagaactcacggagcagcagctccccggtgctctacctcctgaatgt
accccaaacatcgatggaccaaatgccaaatctgttcagagggagcaaagtttacattca
tttcatacgctcttttgtcgacgatgttttaagtatgactgcttcctacatccctttcat
gcaacacccaacacatataagaggaagaacacagaaacagctctggacaacaagccttgt
ggaccacagtgttatcagcatctggagggagctaaggagtttgctgctgcccttactgct
gagcggataaagacaccacctaaacgtccagggggccgcagaagaggaagacttccgaat
aacagtagcagacccagcacccccaccatcagtgtgctggagtcaaaggatacagacagt
gacagagaagcagggactgaaaccgggggagagaacaacgataaagaagaagaagagaaa
aaagatgagacttccagttcctctgaagcaaattctcggtgtcaaacaccaataaagatg
aagccaaatattgaacctcctgagaatgtggagtggagtggtgctgaagcctccatgttt
agagtcctcattggtacttactacgataacttttgtgccattgctaggctaattgggacc
aaaacatgtagacaggtgtatgagtttagagtcaaagagtccagtatcatagcacctgtt
cccactgaggatgtggacactcctccaagaaagaagaaaagaaaacatcggttgtgggct
gcacactgcagaaagatccaactgaaaaaggacggctcctctaaccatgtttacaactat
caaccctgtgaccatccacggcagccttgtgacagttcgtgcccttgtgtgatagcacaa
aatttttgtgaaaagttttgtcaatgtagttcagagtgtcaaaaccgctttcctggatgc
cggtgcaaagcacaatgcaacaccaagcagtgtccgtgctacctggctgtccgagagtgt
gatcctgacctctgtctcacttgtggagctgctgaccactgggacagtaaaaatgtgtcc
tgcaagaactgtagcattcagcggggctctaaaaagcacttactgctggcaccgtctgat
gtggcaggctggggcatctttatcaaagatccagtacagaaaaatgaattcatctcagaa
tactgtggagagattatttctcaggatgaagcagacagaagagggaaagtgtatgacaaa
tacatgtgcagctttctgttcaacttgaacaatgattttgtggtggatgcaacccgcaag
ggcaacaaaattcgttttgctaatcattcagtaaatccaaactgctatgcaaaagttatg
atggttaatggtgaccacaggataggcatctttgctaagagagctatccagactggtgaa
gagttgttctttgattacagatacagccaggctgatgccctgaagtatgtgggcatcgaa
cgagaaatggaaatcccttga
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integrated database retrieval system
