Rattus norvegicus (rat): 313050
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Entry
313050 CDS
T01003
Symbol
Lck
Name
(RefSeq) proto-oncogene tyrosine-protein kinase LCK
KO
K05856
lymphocyte cell-specific protein tyrosine kinase [EC:
2.7.10.2
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04064
NF-kappa B signaling pathway
rno04380
Osteoclast differentiation
rno04650
Natural killer cell mediated cytotoxicity
rno04658
Th1 and Th2 cell differentiation
rno04659
Th17 cell differentiation
rno04660
T cell receptor signaling pathway
rno05135
Yersinia infection
rno05166
Human T-cell leukemia virus 1 infection
rno05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
rno05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
313050 (Lck)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
313050 (Lck)
04660 T cell receptor signaling pathway
313050 (Lck)
04658 Th1 and Th2 cell differentiation
313050 (Lck)
04659 Th17 cell differentiation
313050 (Lck)
09158 Development and regeneration
04380 Osteoclast differentiation
313050 (Lck)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
313050 (Lck)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
313050 (Lck)
09171 Infectious disease: bacterial
05135 Yersinia infection
313050 (Lck)
09163 Immune disease
05340 Primary immunodeficiency
313050 (Lck)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rno01001
]
313050 (Lck)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
rno03036
]
313050 (Lck)
Enzymes [BR:
rno01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
313050 (Lck)
Protein kinases [BR:
rno01001
]
Non-receptor tyrosine kinases
SRC family
313050 (Lck)
Chromosome and associated proteins [BR:
rno03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
313050 (Lck)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_2
SH3_9
ABC1
SH2_1
Haspin_kinase
SH3_16
Kdo
SH3_3
Motif
Other DBs
NCBI-GeneID:
313050
NCBI-ProteinID:
NP_001094179
RGD:
2994
Ensembl:
ENSRNOG00000009705
UniProt:
Q01621
LinkDB
All DBs
Position
5:complement(147172642..147201267)
Genome browser
AA seq
509 aa
AA seq
DB search
MGCVCSSNPEDDWMENIDVCENCHYPIVPLDSKSTLPIRTGSEVRDPLVTYEGSLPPASP
LQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKAN
SLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKH
YKIRNLDNGGFYISPRITFPGLHDLVRHYTNASDGLCTKLSRPCQTQKPQKPWWEDEWEV
PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHPRL
VRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLNVNKLLDMAAQIAEGMAFIEEQNY
IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK
SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLEKGYRMVRPDNCPEELYHLMMLCWKER
PEDRPTFDYLRSVLDDFFTATEGQYQPQP
NT seq
1530 nt
NT seq
+upstream
nt +downstream
nt
atgggctgtgtctgcagctcaaaccccgaagatgactggatggagaacattgacgtgtgt
gaaaactgccactatcccatagtcccactggacagcaagagtacgctgcccatccggacc
ggctctgaagttcgggacccactggtcacctatgagggctccctcccaccagcctccccg
ctgcaagacaacctagttattgccctgcacagctatgagccctcccatgatggagacttg
ggctttgaaaagggtgaacagctccgaatcctggagcagagcggtgagtggtggaaggct
cagtccctgaccactggccaagaaggcttcatccccttcaacttcgtggcgaaagcaaac
agcctggagcctgaaccttggttcttcaaaaatctgagccgtaaggacgccgagcggcag
cttttggcgcccgggaacacgcatggatccttcctgatccgggaaagcgaaagcaccgcc
ggatccttttcactgtcagtcagagacttcgaccagaaccagggagaagtggtgaaacat
tacaagatccgtaacctagacaacggtggcttctacatctcccctcgtatcacttttccc
ggactacacgatctggtccgccattacaccaacgcctctgatgggctgtgcacaaaattg
agccgtccttgccagacccagaagccccagaaaccatggtgggaggacgaatgggaagtt
cccagagagacattgaagttggttgagcggctgggagctggccagttcggggaagtgtgg
atgggatactacaatggacacacgaaggtggcagtgaaaagtctgaagcaagggagtatg
tctcctgatgccttcctggcagaggctaacctcatgaagcagctgcagcacccgcggctc
gtccggctttatgcagtggtcacccaggagcccatctacattatcacagaatacatggag
aacgggagcctagtagatttcctcaagactccctcgggcatcaagttgaacgtcaacaaa
cttttggacatggcagcccagattgcagagggcatggcgttcatcgaagagcagaattac
atccatcgtgacctgcgggctgccaacatcctggtgtctgacacgctgagctgcaaaatt
gcagactttggcctggcacgtctgattgaggacaatgaatacacggcccgggagggggcc
aagtttcccattaagtggacagcaccagaagccattaactatgggacctttaccatcaag
tcagatgtgtggtccttcgggatcctgctgacagagatcgtcacccatggccggatccct
tacccaggaatgaccaaccctgaagtcattcagaacctggaaaaaggctaccgaatggtg
cgacctgacaactgcccggaagagctgtaccacctcatgatgctgtgctggaaggagcgc
ccagaggacaggcccacgtttgactaccttcggagcgttctggatgacttcttcacagcc
acagagggccagtaccagccccagccttga
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