Rattus norvegicus (rat): 314856 Help Entry 314856            CDS       T01003                                  Symbol Mdm2 Name (RefSeq) E3 ubiquitin-protein ligase Mdm2   KO K06643   E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27] Organism rno  Rattus norvegicus (rat) Pathway rno01522   Endocrine resistance rno01524   Platinum drug resistance rno04068   FoxO signaling pathway rno04110   Cell cycle rno04115   p53 signaling pathway rno04120   Ubiquitin mediated proteolysis rno04144   Endocytosis rno04151   PI3K-Akt signaling pathway rno04218   Cellular senescence rno04625   C-type lectin receptor signaling pathway rno04919   Thyroid hormone signaling pathway rno05163   Human cytomegalovirus infection rno05165   Human papillomavirus infection rno05169   Epstein-Barr virus infection rno05200   Pathways in cancer rno05202   Transcriptional misregulation in cancer rno05203   Viral carcinogenesis rno05205   Proteoglycans in cancer rno05206   MicroRNAs in cancer rno05214   Glioma rno05215   Prostate cancer rno05218   Melanoma rno05219   Bladder cancer rno05220   Chronic myeloid leukemia Brite KEGG Orthology (KO) [BR:rno00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04120 Ubiquitin mediated proteolysis     314856 (Mdm2)  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     314856 (Mdm2)    04151 PI3K-Akt signaling pathway     314856 (Mdm2)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     314856 (Mdm2)   09143 Cell growth and death    04110 Cell cycle     314856 (Mdm2)    04115 p53 signaling pathway     314856 (Mdm2)    04218 Cellular senescence     314856 (Mdm2)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     314856 (Mdm2)   09152 Endocrine system    04919 Thyroid hormone signaling pathway     314856 (Mdm2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     314856 (Mdm2)    05202 Transcriptional misregulation in cancer     314856 (Mdm2)    05206 MicroRNAs in cancer     314856 (Mdm2)    05205 Proteoglycans in cancer     314856 (Mdm2)    05203 Viral carcinogenesis     314856 (Mdm2)   09162 Cancer: specific types    05214 Glioma     314856 (Mdm2)    05220 Chronic myeloid leukemia     314856 (Mdm2)    05218 Melanoma     314856 (Mdm2)    05219 Bladder cancer     314856 (Mdm2)    05215 Prostate cancer     314856 (Mdm2)   09172 Infectious disease: viral    05163 Human cytomegalovirus infection     314856 (Mdm2)    05169 Epstein-Barr virus infection     314856 (Mdm2)    05165 Human papillomavirus infection     314856 (Mdm2)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     314856 (Mdm2)    01522 Endocrine resistance     314856 (Mdm2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:rno04131]     314856 (Mdm2)    04121 Ubiquitin system [BR:rno04121]     314856 (Mdm2) Enzymes [BR:rno01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      314856 (Mdm2) Membrane trafficking [BR:rno04131]  Endocytosis   Clathrin-mediated endocytosis    Ubiquitin E3 ligases     314856 (Mdm2) Ubiquitin system [BR:rno04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    MDM2/MDM4 proteins     314856 (Mdm2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  zf-C3HC4_3 Zn_ribbon_RanBP SWIB zf-RING_2 DUF4194 zf-FPG_IleRS Motif Other DBs NCBI-GeneID:  314856 NCBI-ProteinID:  NP_001101569 RGD:  1305332 Ensembl:  ENSRNOG00000006304 UniProt:  A6IGT1 D3ZVH5 LinkDB All DBs Position 7:complement(55176558..55201757) Genome browser AA seq 458 aa AA seqDB search MCNTNMSVSTEGAAGTSQIPASEQETLIIFYIGQYIMTKRLYDEKQQHIVYCSNDLLGDV FGVPSFSVKEHRKIYAMIYRNLVVVSQQDSGTSPSESRCQPEGGSDLKDPVQASQEEKPS SSDVVSRPSTSSRRRAISETEENTDELPGERQRKRHRALSFDESLGLCVLREICCERSSS SEATDTPSHQDLDDGVSDHSADCLDQDSVSDQFSVEFEVESLDSEDYSLSDEGHELSDED DEVYRVTVYQAGESDADSFEGDPEISLADYWKCTSCNEMNPPLPSHCNRCWTLRENWLPD DKGKDKVEISEKAKLESSDQAEEGLDVPDGKKVTEDDAKESSAEDSEEKVAQMLLSQESD DYSQPSTSSSIVYSSQESGKELKEDTQDKEESMESSFSLNAIEPCVICQGRPKNGCIVHG KTGHLMSCFTCAKKLKKRNKPCPVCRQPIQMIVLTYFN NT seq 1377 nt NT seq  +upstreamnt  +downstreamnt atgtgcaataccaacatgtctgtgtctaccgagggtgctgcaggcacctcacagattcca gcgtcggaacaagagactctgattatattttatattggacagtatattatgactaaaaga ttatatgatgagaagcagcagcacattgtgtattgctcaaatgatctcctaggagatgtg ttcggagtcccaagtttctctgtgaaggagcacaggaaaatatatgcaatgatctacaga aacttagtggttgtaagtcaacaagactctggaacatcgccgagtgagagcagatgtcag cctgaaggtgggagtgacctgaaggaccccgtgcaagcatcacaagaagagaaaccttca tcttctgatgtagtttctagaccatctacctcatctagaaggagagcaattagtgaaaca gaagagaacacagatgaactacctggggaacgacagaggaagcgccacagagccctgtcc tttgatgagagcctgggtctgtgtgtgctcagggagatatgctgtgaaagaagcagcagc agcgaggccacagacaccccctcacatcaggatcttgatgatggcgtaagtgaccattct gctgattgcctggatcaggattcagtttctgatcaattcagtgtagaatttgaagttgag tctcttgactcagaagattacagcctgagtgatgaagggcatgagctctcagatgaggat gatgaggtctatcgggtcacagtctatcaggcaggagaaagcgatgcagactcttttgag ggagatcctgaaatttccttagctgactattggaaatgcacctcgtgcaatgaaatgaat cctccccttccatcacactgcaacagatgttggacccttcgtgagaactggcttccagac gataaggggaaagataaagtggaaatttctgaaaaagccaaactggaaagctcagatcag gcagaagaaggcttagatgtgcctgatggcaaaaaagtgacagaggatgatgctaaggag tcatctgctgaggatagcgaggaaaaagtggcccagatgctcctgtcacaggagagtgac gactattcccagccgtcgacttccagtagcattgtttacagcagccaagaaagtggcaaa gagttgaaggaggacacacaagacaaagaggaaagtatggaatccagcttctctctgaac gccatcgagccatgtgtgatttgccaggggcggcctaaaaatggttgcattgttcacggc aaaaccggacacctgatgtcatgtttcacgtgtgcaaagaagctaaagaagaggaataag ccctgccccgtgtgcagacagccgatccaaatgattgtgctcacgtacttcaactag

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