Rattus norvegicus (rat): 315330
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Entry
315330 CDS
T01003
Symbol
Espl1
Name
(RefSeq) separin
KO
K02365
separase [EC:
3.4.22.49
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04110
Cell cycle
rno04114
Oocyte meiosis
rno05166
Human T-cell leukemia virus 1 infection
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
315330 (Espl1)
04114 Oocyte meiosis
315330 (Espl1)
09160 Human Diseases
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
315330 (Espl1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
rno01002
]
315330 (Espl1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
rno03036
]
315330 (Espl1)
Enzymes [BR:
rno01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.22 Cysteine endopeptidases
3.4.22.49 separase
315330 (Espl1)
Peptidases and inhibitors [BR:
rno01002
]
Cysteine peptidases
Family C50: separase family
315330 (Espl1)
Chromosome and associated proteins [BR:
rno03036
]
Eukaryotic type
Sister chromatid separation proteins
Separase
315330 (Espl1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Peptidase_C50
CHAT
Motif
Other DBs
NCBI-GeneID:
315330
NCBI-ProteinID:
NP_001164073
RGD:
1306266
Ensembl:
ENSRNOG00000012835
UniProt:
D3ZDT7
LinkDB
All DBs
Position
7:135302460..135329570
Genome browser
AA seq
2109 aa
AA seq
DB search
MRNFKGVKFATLLCCKRETQELLPDLKEFLSRSRTDSVSSRTDAERRQVCDTILRACTQQ
LTAKLDGPGHLRSILDLAELACDGYLLSTPQRPPLYLERILFILLRNGLTQGNPDAVLRL
AQPLHACLVQNSREAAPQDYEAVTRGTFSLLWKGAEALSERRAAFSARLKALSFLVLLED
GSLPCEVPHFASPTACRVVAAYQLFDATGQGLDAADADFVYDLLSRHVIRVLVGEGGRAS
GPLSPQRALCLLELTLEHCRRLCWNQHHHKATIAVEKTRDHLGNSNVAPSLQLCQMGVEL
LEAVEERPGAVAQLLMKAAAILNSSMDGPSPPLRALYDSCQFFLSGLERTIKRHYGVDAI
LNLFAFLGGYHSLVRHLREASEASSKQQQSLLQMHFHTLHLFTGIVYDFAQGCQVAELAQ
LVDSCRSAVVWMLEALEGLSGGELADYLGVTASYTSNLAYSFFSQKLYEEACAISEPVCQ
HLGLAKSGACPEVPPEKLHRCFRLHVESLKKWGKQAQGCKMVTLWLAALKPYGLQHMVEP
VTFWVRVKMDAAKAGDKELQLQTLRDSLSCWDPEMQSLLLREELQAYKAVRADTGQERFN
VICDLLELSPEDTAAGAWARATHLVELAQVLCYHSFAQQTNCSALDAIQEALQLLESVSP
EAQEQDRLLDDKAQALLWLYICTLEAKMQEGIERDRRAQAPSNLEEFEVNDLNYEDKLQE
DRFLYSNIAFNLAADAAQSRCLDQALTLWKEVLTKEPAPAVRCLQQTAASLQILVAIYQL
VAKPLQALETLLLLQIVSKRLQDHAKAVSSSCQLTQLLLNLGCPSYAQLYLEEAESSLKN
LDQATDTCQLLSLTCALLRSQLCWACQKVTEGVSLLLSVLRDPALQKSSKAWYLLRVQAL
QILAFYLSLSSNLLSSALREELWDQGWQTPETALIDAHKLLRSIIILLMGGDVLSVQKAA
VESPFLDYGENLVQKWQVLTEVLTCSERLVSRLGRLGNVSEAKAFCLEALKLTTKLQIPR
QCALFLVLKGELELARGDTDLCQSDLQQVLFLLESSTEFGVVTQHPDSVKRVHTQKGTHK
AQVPCSPPLPEEEPFLRGPALELVATVLKEPGPIQPSGNSSPVLKTKASPKPGFLSHLPS
CDCLLCASPALSTVCLRWVLVTAGVRLTTGHKAQGLDLLQAVLKGCPAATKRFTQNLQTS
LNHKAPPSCVPSLFDEIMAQVYTHLALECLNQTSEKSLGKVLASGLKFVATRIQYLEFWQ
ASLLLVQALAKLARFSCCTSELFASAWGWQPPLVKIPPVLEPSKIRRQKCSGQGRQRVAS
APSPLHSSSQEGLEEGPPCTPKPPGRARQAGPRVPFTIFEDIHPTKSKLKVPLAPRVHRR
AQTRLKVNFSDDSDLEDLVSAETQLVEEPKRRGTASRTRGQSRKGPSLKTDAAVAVGSTP
GHPSLSGRTRRARKVASRHCEGVGASLGPEIMRSIPEEELMDSQLEKSFEILRASDGEDS
ASGEKAAAAEPGLPIGEREVLRRDSSKAERPVLYPDTEADSDLSPWLPPFSIPAPIDLST
LDSIADSLSIAFRGISHCPPSGLYAHLCRFLALCLGHRDPYATAFLVAESVSITCRHQLL
THLHRQLSKAQKQQGSPELAEHLQRLDLKERPGGVPLARVQHLFSFRALGSGCFPQAEKD
SFQKRLALIPSGVTVCVLALATLQPGTLSNTLLLTRLEKDNPPITVKIPTAQSKFPLSAV
LKEFDAIQKDQKENSGCTEKRAWWTGRLALDQRMEELITSLEEHVLGCWRGLLLPCSTDP
GLSQEASQLQELLHECGWEYPDYTLLKVILSGARILSSQDVQALACGLCPAQPERAQVLL
SEAVGRVQSQAAPPSQHLVLVLDKDLQKLPWESMPCLRALPVTRLPSLRFLLSYSIAKEA
GASSVLSQGVDPRNTFYVLNPHSNLSSTEERFRASFSSEAGWKGVIGEVPSLEQVQAALT
EHDLYIYAGHGAGARFLDGQAVLRLNCRAVALLFGCSSAALAVHGNLEGAGIVLKYIMAG
CPLFLGNLWDVTDRDIDRYTEALLQGWLGAGPGAPLLHYVSQARQAPRLKYLIGAAPVAY
GLPVSLQTS
NT seq
6330 nt
NT seq
+upstream
nt +downstream
nt
atgaggaacttcaaaggagtcaagttcgccactctactttgctgcaagagagagacccag
gagttgctgcctgacttgaaggagttcctgtctagatctcgaactgattcagtcagcagc
agaaccgatgctgagagaagacaggtctgtgacaccatcctgagggcttgcacccagcag
ctgactgccaagcttgacggccctggtcacctgagaagtatcctggacctggcagagctg
gcctgtgacggctacttgttgtctaccccacagcgccctcccctctatctggaacgcatt
ctttttatcttacttcggaatggtttgactcagggaaacccagacgctgtgctccgcctt
gcccagcctctccatgcctgcttggtacagaactctcgagaggctgcccctcaggactat
gaggctgtgacccggggtactttttctctgctttggaagggagcagaagccctgtcagag
cggcgagctgcattctcagctaggctgaaggccttgagtttcttagtgcttttggaggat
ggcagcctcccttgtgaggtccctcactttgcttctccaacagcctgtcgggtagttgcc
gcctatcagctgtttgatgctactggacaaggtctagatgcagctgacgctgacttcgtc
tatgacttgctttctaggcatgtgatcagagtcttagtaggcgagggtggtagggcttct
ggtccgctctctcctcagagggccctctgcctcttggaactcaccttggaacattgtcgt
cgactctgctggaaccagcaccaccacaaggctaccatagcagtggagaagactcgagat
cacctaggaaatagcaatgtagctcccagcctccaactgtgccagatgggggttgagctg
ctggaagctgtggaagaaagaccaggggcagtggcccagctcctgatgaaggcagctgct
attctgaacagcagtatggatgggccatcacccccgctccgggcattgtatgacagctgc
cagttcttcctttcaggcctggagagaaccatcaagaggcactatggagttgatgccata
ttgaatctctttgcttttcttgggggataccactcccttgtccggcacctgcgagaagcc
tccgaagcgtcctctaagcagcagcagagcctgctccagatgcacttccataccctccac
ctcttcactgggattgtgtatgactttgcccaaggctgtcaggtagctgagcttgctcag
ctagtggacagttgcagatctgctgttgtctggatgttggaggccttagagggcctgtct
ggtggagagctggctgactacctgggcgtgactgcctcttacaccagcaacttggcctac
agcttctttagtcagaagctctatgaggaggcttgtgccatctcagagccagtctgtcag
cacttgggcttggctaagtcaggcgcttgtcccgaagtgcctcctgagaagctacatagg
tgcttccggctgcatgtggagagtttgaagaaatggggtaaacaggcccagggctgcaag
atggtgaccttatggctggcagctctgaaaccctacggtctccaacacatggttgagcca
gtcactttctgggttcgggtcaaaatggatgcagccaaggcaggagacaaggagctacaa
ctgcagactttgcgagacagcctaagttgctgggacccagagatgcagtctctgctactg
agggaggagctgcaggcctataaggcagtacgggctgacactgggcaggaacgcttcaac
gtcatctgcgatctgcttgagctcagccctgaggacacagcagctggagcctgggcacga
gctacccacctggtggaattggcccaagtgctgtgctaccatagctttgcccagcagaca
aactgctctgccttggatgctatccaggaggccctgcagcttctggagtccgtgagtccc
gaggcacaggagcaggaccgccttctagatgacaaagcacaggccctgctatggctctac
atctgcaccttggaggccaaaatgcaggaaggtatcgagcgggatcggagggcccaggcc
cctagtaacttggaggaatttgaagtcaatgacctgaactatgaagataaactgcaggaa
gatcgctttctatacagtaacattgccttcaatctggctgctgatgcagcgcagtccaga
tgcctggaccaggccctgactctgtggaaggaagtgctcaccaaggagccagccccagct
gtgcggtgtctccagcagacggcagcctccctgcaaatcctggtggccatctatcagttg
gtggcaaagcccttgcaggctctggagaccctcctgctccttcagattgtatctaagaga
ctacaggatcatgcaaaggcagtcagctcttcctgccagcttacccagctactcttgaac
cttggctgtcccagctatgcccagttgtatctggaagaggcagagtcaagcctgaagaat
ctggaccaagcgactgacacgtgccagctgctttccctgacctgtgctctgcttcgaagc
cagctctgctgggcttgccagaaggtgactgagggcgtttctctgttgctttctgtcctt
cgagatcctgccctccagaagtcatccaaggcttggtacttgctacgtgtccaggccctg
caaattctggctttctacctcagcctctcgtccaacctcctctcaagtgccctacgagag
gagctctgggatcaaggctggcagaccccagagacagcactgatagatgcccacaagctt
ctgagaagcatcatcatcttgctgatgggtggcgatgtgctctccgttcagaaagcagct
gtggagtcgccctttctggattacggtgagaatctggtgcagaaatggcaagttctcaca
gaggtgctgacctgctcggagaggctggtcagccgcctgggccgcctggggaacgtgagt
gaagccaaggccttttgcttggaggccctaaaacttaccaccaagctgcagatacctcgc
cagtgtgccctgttccttgtactgaagggtgagctggagctggcccggggagacactgac
ctctgtcagtcagacttgcagcaggttctgttcttgctcgagtcttccacagagtttggt
gtggtgacacagcacccagactcagtgaagagggtgcacacgcagaaagggacgcataag
gctcaagtcccctgttccccacctctaccagaagaggaacccttcctgagaggccctgcc
cttgagctggtggccactgtgctcaaggagcccggtcccatccaaccctctggaaactcc
tccccggtcctcaagaccaaggcatcacccaagcctggcttcctgtctcacttgcccagc
tgtgattgcttactgtgtgccagtcctgccctctccaccgtctgtctgcgctgggtgttg
gtcactgcaggagtgaggctcaccacaggtcataaagctcagggtctggatctgctgcaa
gctgtgctgaagggttgccctgcagccaccaagcgcttcacacagaatcttcaaacttct
ctgaatcacaaagcacccccctcttgtgttccaagcctctttgatgagatcatggctcaa
gtgtacacacacttggcattagagtgcctgaatcagacatctgaaaagagcctgggaaag
gtcctggcgtcaggactgaagtttgtggcaacacggatacaatacttagagttctggcaa
gccagcctgctcttggttcaggcccttgcaaagctggcccgcttcagctgctgtactagc
gaactctttgcaagcgcctggggctggcagccaccattagtaaaaatcccgccagtcctt
gagccttctaagattcggagacaaaaatgctctggacaggggcgccagcgggtagcctct
gccccctcacccctccatagcagctctcaggaaggtctggaagaagggccaccttgtaca
cctaagcccccaggccgtgctaggcaagccggccctcgtgtccctttcaccatatttgaa
gacatccaccccacaaagagcaagcttaaggttcccttggctcccagggtccacaggcgg
gcccagactcgactcaaggtgaacttcagcgatgacagcgacctggaagaccttgtctca
gctgaaacacaacttgtggaggaacctaagaggcgagggactgcttcccgcacccggggt
cagagtaggaagggccctagcttaaagacagatgcagcggttgccgtaggtagtacccct
ggacatcccagtctcagtgggaggactcggagggccaggaaggtggcttcaagacattgt
gaaggtgtcggggccagcctgggacccgaaatcatgagaagcatccctgaagaggagctg
atggacagccagctagaaaagagctttgagattctcagggcttctgatggggaagactca
gcctcaggcgagaaggcagcagctgcagagcctggtctacccataggagagcgtgaggtg
ttgagacgggactccagcaaggcagagcgacctgtcttgtaccctgatacagaggccgat
agtgaccttagtccttggctcccacccttctcaattcctgcacccattgatctttctacc
ctggattccatcgctgactcattgagcattgcttttcgtggtattagtcactgccctcca
agtgggctctacgctcacctctgccgctttttggccttgtgtctgggccaccgggatccc
tatgccactgcgttccttgtagcagagtctgtctccatcacctgccgtcaccagctactc
acccatttgcaccgacagctcagcaaggcccagaagcagcaaggctcacctgaactagca
gagcatctacagaggctggacttgaaggagaggcccggaggtgtcccactggcccgcgtg
cagcacctcttttccttcagggctttgggatctggctgcttcccccaggcagagaaggac
agtttccagaagcgcctggctctcatccccagtggggtgactgtctgcgtgttggccctg
gccaccctccagcctggaaccttgagcaacactctcttactgacccgcctggaaaaggac
aaccccccaattactgtgaagatccccactgcccaaagtaagttcccactaagtgcggtg
ctgaaagagttcgatgccatccagaaggaccagaaagagaacagcggctgtactgagaaa
cgagcgtggtggacgggccggctagcactagaccaaaggatggaggaactcattacctcc
ctagaggagcatgtgctgggctgctggagggggctgctgctgccgtgtagcaccgaccct
ggcctttcccaggaggcctcccaactacaagagttgctgcacgaatgtggctgggaatat
cctgattacactctcctaaaagtcattcttagtggggccagaatcctctccagccaggat
gttcaggccttggcatgtgggctgtgcccagcccaacctgagcgagcccaagtgctcctg
agcgaggcagtaggacgggtacagagccaggcagcccctccgagtcaacatcttgtactg
gtgttagacaaggacctgcagaagctgccgtgggaaagcatgccatgcctccgagcactg
ccggtcacccggctgccctccctccgcttcctgctcagctactcaatcgctaaggaggct
ggggcctcatcagtgctgagccaaggtgttgatccacgcaataccttctatgtgctaaac
cctcacagtaacctgtcgagcacggaggagagatttcgagccagttttagcagtgaagcc
ggatggaaaggcgtgattggggaagtgcccagccttgagcaggtgcaggctgccctgaca
gagcatgatttatatatctatgcaggacatggagctggtgcccgcttccttgatgggcag
gctgtcctgcggctgaactgccgggcagtggccctactgttcggctgcagcagtgcagcc
ctcgcagtgcatggaaacctggagggagctggtattgtgctcaagtacatcatggctggc
tgccccttgttcctaggtaatctctgggatgtgactgaccgtgatattgaccgttacaca
gaggctttgctgcagggctggctgggagcaggcccaggggctccccttctccactatgtc
agccaagcccgccaggccccacgactcaagtatcttattggtgctgcacctgtagcctac
ggcctacctgtctctctacaaacatcctga
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