Rattus norvegicus (rat): 363984
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Entry
363984 CDS
T01003
Symbol
Ikbke
Name
(RefSeq) inhibitor of nuclear factor kappa-B kinase subunit epsilon
KO
K07211
inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:
2.7.11.10
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04620
Toll-like receptor signaling pathway
rno04621
NOD-like receptor signaling pathway
rno04622
RIG-I-like receptor signaling pathway
rno04623
Cytosolic DNA-sensing pathway
rno04625
C-type lectin receptor signaling pathway
rno04657
IL-17 signaling pathway
rno04936
Alcoholic liver disease
rno05160
Hepatitis C
rno05161
Hepatitis B
rno05162
Measles
rno05164
Influenza A
rno05165
Human papillomavirus infection
rno05167
Kaposi sarcoma-associated herpesvirus infection
rno05168
Herpes simplex virus 1 infection
rno05169
Epstein-Barr virus infection
rno05171
Coronavirus disease - COVID-19
rno05207
Chemical carcinogenesis - receptor activation
rno05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
363984 (Ikbke)
04621 NOD-like receptor signaling pathway
363984 (Ikbke)
04622 RIG-I-like receptor signaling pathway
363984 (Ikbke)
04623 Cytosolic DNA-sensing pathway
363984 (Ikbke)
04625 C-type lectin receptor signaling pathway
363984 (Ikbke)
04657 IL-17 signaling pathway
363984 (Ikbke)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
363984 (Ikbke)
09172 Infectious disease: viral
05161 Hepatitis B
363984 (Ikbke)
05160 Hepatitis C
363984 (Ikbke)
05171 Coronavirus disease - COVID-19
363984 (Ikbke)
05164 Influenza A
363984 (Ikbke)
05162 Measles
363984 (Ikbke)
05168 Herpes simplex virus 1 infection
363984 (Ikbke)
05167 Kaposi sarcoma-associated herpesvirus infection
363984 (Ikbke)
05169 Epstein-Barr virus infection
363984 (Ikbke)
05165 Human papillomavirus infection
363984 (Ikbke)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
363984 (Ikbke)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
363984 (Ikbke)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rno01001
]
363984 (Ikbke)
Enzymes [BR:
rno01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
363984 (Ikbke)
Protein kinases [BR:
rno01001
]
Serine/threonine kinases: Other
IKK family [OT]
363984 (Ikbke)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TBK1_CCD1
Pkinase
TBK1_ULD
PK_Tyr_Ser-Thr
ABC1
Pkinase_fungal
Kinase-like
RH_dom
Motif
Other DBs
NCBI-GeneID:
363984
NCBI-ProteinID:
NP_001102324
RGD:
1308352
Ensembl:
ENSRNOG00000025100
UniProt:
A6IC17
D4A5E7
LinkDB
All DBs
Position
13:complement(45264404..45290737)
Genome browser
AA seq
717 aa
AA seq
DB search
MQSTTNYLWHTDDLLGQGATANVYKARNKKSGEVVAVKVFNSASYRRPPEVQVREFEVLR
RLDHENIVKLFAVEETGGSRQKVLVMEYCSSGSLLSVLEDPENTFGLPEEEFLVVLRCVV
AGMNHLRENGIVHRDIKPGNIMRLVGKEGQSIYKLSDFGAARKLDDDEKFVSVYGTEEYL
HPDMYERAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFIPFGGPRRNKEIMYRITTE
KPAGAISGTQKQENGPLEWSYSLPITCRLSVGLQSQLVPILANILEAEQAKCWGFDQFFA
ETSDILQRTVIHVFSLPQAVLHHIYIHAHNTIAIFLEAVYEQTNVAPKHQEYFFEGHPCV
LEPSLSAQHIAHTAASSPLTLFSMASDTPKGLAFRDPALDVPKFVPKVDLQADYSTAKGV
LGAGYQALWLARVLLDGQALMLRGLHWVLVVLQNTCQQTLEITRTALLFLSSSLGTERLS
SGAGMLDIQELKEATELRSRLQTFSEVLSKCSHNVTETQRSLSCLVGELLKSRDQIHEDN
RSIQKIQCCLDKMHFIYKQFKKSRMRPGLSYNEEQIHKLDKVNFSHLAKRLLQVFQEECA
QTYQVSLVTHGKRMRQVQKAQNHLHLIGHSVATCNSEARGAQESLAKMFDQLLLDRASKQ
GAEVSPQPMATHPGPDPKDLVFHMQELCNDMKLLAFDLQDNNRLIERLHRVPPTPEV
NT seq
2154 nt
NT seq
+upstream
nt +downstream
nt
atgcagagtaccactaactacctgtggcatactgatgacctgctagggcagggggccact
gccaatgtgtacaaggcccggaataagaaatccggggaggtggttgctgtaaaggtcttc
aactcagccagctaccggcggccccctgaggtacaagtgagggagttcgaggtcttgcgg
aggctggatcatgagaacatcgtgaagctattcgcagtggaggaaacgggaggcagccgg
cagaaggtgctagtgatggagtactgctccagtgggagcctgctgagcgtgctggaagac
cctgagaacacattcggccttcctgaggaggagttcctggtggtactgcgctgtgtggtg
gctggcatgaaccacctgcgggagaatggcattgtccaccgtgacatcaagcccgggaat
atcatgcgcctggtaggcaaggaggggcagagcatctacaagctgtctgacttcggggct
gcccggaagctggacgacgatgagaagtttgtttctgtctatggtacagaggagtacctg
caccctgacatgtatgagcgggcagtgcttcgcaaaccccagcaaaaggcgttcggggtg
acagtggatctctggagtattggggtgaccttgtaccacgcagccaccggtagtctgccc
ttcatcccctttggtgggccccggcgcaacaaggagatcatgtataggatcaccacagag
aagccagctggggccatttccgggactcagaagcaggaaaatggtcccctggaatggagc
tacagcctccccatcacctgtagactgtctgtggggctgcagagtcagctagtgcccatc
ctggccaacatcctggaggccgaacaggctaaatgctggggcttcgatcagttctttgca
gagaccagtgacatcctgcagcgaactgtcatccatgtcttctccctgccccaggcggtt
ttgcatcacatctacatccatgcccacaacacgattgccatctttttggaggctgtatat
gaacagaccaacgtggcccccaaacaccaagaatacttcttcgagggtcacccttgtgtc
ctcgagccaagcctctcagcccagcacatcgcccacacagctgccagcagccctctaact
ctgttcagcatggccagcgacacacccaaggggctggccttcagggaccctgctctggat
gtcccaaagttcgtccctaaggttgacctacaggccgattacagcaccgctaagggcgtg
ctgggcgctggttaccaggccttgtggctggcgcgggtcctgctggatggacaggcgttg
atgcttcgagggttacactgggtcctggtggtgcttcagaacacgtgccaacagacactg
gagatcacacggacagccctcctcttcctcagtagcagcctgggcactgaaaggctcagc
agtggagctgggatgcttgacatccaggaactaaaggaagccacggagctgaggtccagg
ctgcagactttctcagaggtcctgtctaagtgttcccacaatgtcacagaaacccaaagg
agcctgagttgtctggttggagagcttttgaagagccgggatcagattcatgaggataac
agaagtatccagaagattcagtgttgtttggacaagatgcacttcatctacaaacagttc
aagaagtctaggatgaggccaggcctcagctacaatgaggagcagatccacaagctggat
aaggtaaattttagtcacctagccaagaggctgctgcaggtgttccaggaggagtgtgca
cagacgtatcaggtgtcactggtcacacatggcaagcggatgaggcaggtgcagaaggcc
cagaaccacctgcacctcattggccactccgtggctacctgtaactcagaagcccgggga
gcccaggagagcctggccaagatgtttgatcagctcctcctggacagagcttccaaacag
ggagctgaggtctcaccacaacctatggcaactcatcccggccccgatccgaaggacctg
gtcttccacatgcaggaactttgtaatgatatgaagctattggcctttgatctccaggac
aacaacagactcatcgaacggctacatagagttccaccaacaccagaagtctga
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