Rattus norvegicus (rat): 497672
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Entry
497672 CDS
T01003
Symbol
Brca1
Name
(RefSeq) breast cancer type 1 susceptibility protein homolog
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno01524
Platinum drug resistance
rno03440
Homologous recombination
rno03460
Fanconi anemia pathway
rno04120
Ubiquitin mediated proteolysis
rno04151
PI3K-Akt signaling pathway
rno05206
MicroRNAs in cancer
rno05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
497672 (Brca1)
09124 Replication and repair
03440 Homologous recombination
497672 (Brca1)
03460 Fanconi anemia pathway
497672 (Brca1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
497672 (Brca1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
497672 (Brca1)
09162 Cancer: specific types
05224 Breast cancer
497672 (Brca1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
497672 (Brca1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
rno01009
]
497672 (Brca1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
rno04121
]
497672 (Brca1)
03036 Chromosome and associated proteins [BR:
rno03036
]
497672 (Brca1)
03400 DNA repair and recombination proteins [BR:
rno03400
]
497672 (Brca1)
Enzymes [BR:
rno01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
497672 (Brca1)
Protein phosphatases and associated proteins [BR:
rno01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
497672 (Brca1)
Ubiquitin system [BR:
rno04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
497672 (Brca1)
Multi subunit type E3
BRCC complex
497672 (Brca1)
Chromosome and associated proteins [BR:
rno03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
497672 (Brca1)
DNA repair and recombination proteins [BR:
rno03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
497672 (Brca1)
BRCA1-A complex
497672 (Brca1)
BRCA1-B complex
497672 (Brca1)
BRCA1-C complex
497672 (Brca1)
BRCA complex
497672 (Brca1)
FA (Fanconi anemia) pathway
Downstream FA components
497672 (Brca1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-C3HC4
zf-C3HC4_2
zf-RING_UBOX
zf-C3HC4_4
zf-RING_2
BRCT_2
zf-C3HC4_3
zf-RING_5
RING_XB3-XBAT31
zf-RING_6
zf-ANAPC11
zf-Nse
zf-RING_10
zf-rbx1
Prok-RING_4
RTT107_BRCT_5
Baculo_IE-1
Motif
Other DBs
NCBI-GeneID:
497672
NCBI-ProteinID:
NP_036646
RGD:
2218
Ensembl:
ENSRNOG00000020701
UniProt:
O54952
A6HJD2
G3V8S5
Structure
PDB
PDBj
LinkDB
All DBs
Position
10:complement(86917693..86978012)
Genome browser
AA seq
1817 aa
AA seq
DB search
MDLSAVRIQEVQNVLHAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
CPLCKNEITKRSLQGSARFSQLVEELLKIIDAFELDTGMQCANGFSFSKKKNSSSELLNE
DASIIQSVGYRNRVKKLRQIESGSATLKDSLSVQLSNLGIVRSMKKNRQTQPQNKSVYIA
LESDSSEERVNAPDGCSVRDQELFQIAPGGAGDEGKLNSAKKAACDFSEGIRNIEHHQCS
DKDLNPTENHATERHPEKCPRISVANVHVEPCGTDARASSLQRGTRSLLFTEDRLDAEKA
EFCDRSKQSGAAVSQQSRWADSKETCNGRPVPRTEGKADPNVDSLCGRKQWNHPKSLCPE
NSGATTDVPWITLNSSIQKVNEWFSRTGEMLTSDNASDRRPASNAEAAVVLEVSNEVDGC
FSSSKKIDLVAPDSDNAVMCTSGRDFSKPVENIINDKIFGKTYQRKGSRPHLNHVTEIIG
TFTTEPQIIQEQPFTNKLKRKRSTCLHPEDFIKKADLTVVQRISENLNQGTDQMEPNDQA
MSITSNGQENRATGNDLQRGRNAHPIESLRKEPAFTAKAKSISNSISDLEVELNVHSSKA
PKKNRLRRKSTRCVLPLEPISRNPSPPTCAELQIESCGSSEETKKNNSNQTPAGHIREPQ
LIEDTEPAADAKKNEPNEHIRKRSASDAFPEEKLMNKAGLLTSCSSPRKPQGPVNPSPER
KGIEQLEMCQMPDNNKELGDLVLGGEPSGKPTEPSEESTSVSLVPDTDYDTQNSVSILEA
NTVRYARTGSVQCMTQFVASENPKELVHGSNNAGSGSECFKHPLRHELNHNQETIEMEDS
ELDTQYLQNTFQVSKRQSFALFSKLRSPQKDCTLVGARSVPSREPSPKVTSRGEQKERQG
QEESEISHVQAVTVTVGLPVPCQEGKPGAVTMCADVSRLCPSSHYRSCENGLNTTDKSGI
SQNSHFRQSVSPLRSSIKTDNRKTLTEGRFEKHTERGMGNETAVQSTIHTISQNNRGDAC
QEASSGSVIEVHSTGENVQGQLDRNRGPTVNTVSLLDSTQPGVSKQSAPVSDKYLEIKQE
SKAVSADFSPCLFSDHLEKPMRSDKIFQVCSETPDDLLDDVEIQENASFGEGGITEKSAI
FNGSVLRRESSRIPSPVTHASKSRSLHRGSRKLEFSEESDSTEDEDLPCFQHLLSRVSST
PELTRCSSVVTQRVPEKAKGTQAPRKSSISDCNNEVILVEASQEYQFSEDAKCSGSMFSS
QHSAALGSPANALSQDPDFNPPSKQRRHQAENEEAFLSDKELISDHEDMAACLEEASDQE
EDSIIPDSVASGYESEANLSEDCSQSDILTTQQRATMKDNLIKLQQEMAQLEAVLEQHGS
QPSGHPPCLPADPCALEDLPDPEQNRSGTAILTSKNINENPVSQNPKRACDDKSQPQPPD
GLPSGDKESGMRRPSPFKSPLTSRRCSARGHSRSLQNRNSTSQEELLQPVELEKSCEPHN
LTGRSCLPRQDLEGTPYLESGISLFSSRDPDSESPKVPALVCTAPASTSALKISQGQVAG
SCRSPAAGGADTAVVEIVSKIKPEVTSSKERAERDISMVVSGLTPKEVMIVQKFAEKYRL
ALTDVITEETTHVIIKTDAEFVCERTLKYFLGIAGGKWIVSYSWVIKSIQERKLLSVHEF
EVKGDVVTGSNHQGPRRSRESQEKLFEGLQIYCCEPFTNMPKDELERMLQLCGASVVKEL
PLLTRDTGAHPIVLVQPSAWTEDNDCPDIGQLCKGRLVMWDWVLDSISVYRCRDLDAYLV
QNITCGRDGSEPQDSND
NT seq
5454 nt
NT seq
+upstream
nt +downstream
nt
atggatttatctgctgttcgaattcaagaagtacaaaatgtccttcatgctatgcagaaa
atcttggagtgtccaatctgtttggaactgatcaaagaaccggtttccacaaagtgcgac
cacatattttgcaaattttgtatgctgaaactccttaaccagaagaaaggaccttcccag
tgtcctttgtgtaagaatgagataaccaaaaggagcctacaaggaagtgcaaggtttagt
caacttgttgaagagctgctgaaaatcattgatgcttttgagcttgacaccggaatgcag
tgtgcaaatggttttagtttttcaaaaaagaaaaatagttcttctgagcttctgaatgag
gacgcttctatcatccagagtgtgggctaccgaaaccgcgtcaaaaaacttcgacagatt
gagtctggaagtgccaccttgaaggacagtctcagtgtccagttgtctaaccttgggatt
gtgagatcaatgaagaaaaataggcagacacaacctcaaaacaaatctgtctacattgct
ttagaatctgattcttctgaggagagagtaaatgcacccgatggctgcagtgtgagagat
caggaattgtttcagatcgcccctggaggagctggagatgaaggcaagttgaactctgca
aaaaaggctgcttgtgacttttctgagggcataagaaacattgaacatcatcaatgcagt
gataaagatttgaaccccactgagaatcatgcaactgaaaggcatccagaaaaatgtccg
cgtatttctgttgcaaacgtgcacgtggagccgtgtggcacagatgctcgtgccagctca
ttacagcgtgggacccgcagtttattgttcactgaggacagactggatgcagaaaaggct
gaattctgtgatagaagcaaacagtctggcgcagcagtgagccagcagagcagatgggct
gacagtaaagaaacatgtaatggcaggccggttccccgcactgagggaaaggcagatcca
aatgtggattccctctgtggtagaaagcagtggaatcatccgaaaagcctgtgccctgag
aattctggagctaccactgacgttccttggataacactgaatagcagcattcagaaagtg
aatgagtggttttccagaactggtgaaatgttaacttctgacaatgcatctgacaggagg
cctgcgtcaaatgcagaagctgctgttgtgttagaagtttcaaatgaagtggatggatgt
ttcagttcttcaaagaaaatagacttagttgcccctgattccgataatgctgtaatgtgt
acaagtggaagagacttctccaagccagtagagaatattatcaacgataaaatatttggg
aaaacctatcagagaaagggaagccgccctcacttgaaccatgtgactgaaattataggc
acatttactacagaaccacagattatacaagagcagcccttcacaaataaattaaaacgc
aaaagaagtacatgccttcatcctgaggactttatcaagaaagcagatttaacagttgtt
caaaggatttctgaaaatttaaatcagggaactgaccaaatggagccaaatgaccaagca
atgagtattaccagtaacggtcaggagaacagagcaacaggtaatgatcttcagagaggg
agaaatgctcatccaatagaatcattgagaaaggaacctgctttcacagctaaagccaaa
tctataagcaacagtataagtgatttggaggtagaattaaatgttcacagttcaaaagca
cctaagaaaaataggctgaggaggaagtctaccaggtgtgttcttccactcgaaccaatc
agtagaaatccgagcccacctacttgtgctgaacttcagatcgagagttgtggtagcagt
gaagaaacaaagaaaaacaattccaaccaaaccccagccgggcacattagagagcctcaa
ctcatcgaagacacagaacccgcagctgatgccaagaagaacgagccaaatgaacatata
aggaagagaagtgccagtgatgcgttcccagaagagaaattaatgaacaaagctggttta
ttaactagctgttcaagtcctaggaagcctcaaggacctgtcaatcctagccctgagaga
aaaggaatagagcaacttgaaatgtgccagatgcctgataataacaaagaactcggggat
ttggtcctgggaggagagcccagtgggaaacctactgaaccatctgaggagagcaccagt
gtgtccttggtacccgacacagactacgacacccagaacagtgtctcaatactggaagcg
aacactgtcagatatgcaagaacaggatcagttcagtgtatgactcagtttgtcgcaagt
gaaaaccccaaggaacttgtccatggttctaacaatgctggaagtggctcggagtgcttc
aagcacccattgagacatgaacttaaccacaatcaagagacaatagaaatggaagacagt
gaacttgatactcagtatttgcagaatacatttcaagtttcaaagcgtcagtcatttgct
ttattttcaaaacttagaagtccccaaaaggactgtactctggtaggtgcccgctctgtg
ccctcaagggaaccaagtccaaaggtgacttctagaggtgaacaaaaagaacgtcaggga
caagaagagtctgaaatcagtcatgtacaggcagtcacagtcacagtaggcttacctgtg
ccctgtcaggaaggtaagccaggtgctgttacaatgtgtgctgatgtttctaggctttgt
ccgtcatctcattatagaagctgtgagaatggactcaacaccacagataaatctggaatt
tcacaaaactcacattttagacaatcagtttctcccctcaggtcatctataaaaactgac
aatagaaaaactctgacagagggacgatttgagaaacatactgaaaggggaatgggaaat
gagactgctgttcaaagtacaatacacacaattagtcaaaataacagaggagatgcttgt
caagaagccagctcaggcagtgttattgaagtacattccactggtgaaaacgtccagggg
caactagatagaaacagagggcctacggtaaacaccgtgtctctattagatagtacacag
cctggtgtctctaagcagagtgctcctgtaagtgataagtatcttgaaataaagcaggag
agtaaggctgtcagtgcagacttctctccatgtctgttctcagatcatcttgaaaaacct
atgagaagtgataagatttttcaggtttgctctgagacacctgatgacctgttggatgat
gttgaaatacaggaaaatgctagcttcggtgaaggtggcataacggaaaagtctgctatt
tttaatggaagtgtcctgagaagagagtccagtaggatccctagccctgtaacccatgca
tcgaagtcgcggagtctccacagagggtctaggaaattagaattctcagaagagagcgac
tccactgaggatgaagaccttccctgcttccagcacttgctgagcagagtaagcagcaca
cccgaacttaccagatgcagcagtgtggtgacacagcgtgtgccagagaaagcgaagggg
acccaagcaccccggaagagtagcatcagtgactgcaataatgaggtgatcttggtagag
gcatctcaggaatatcagtttagtgaggatgcaaaatgctctggcagcatgttctcctca
cagcacagtgctgccctaggttcacctgcaaatgcactctcccaggatcccgattttaat
ccaccttccaaacaaaggcgtcaccaggctgagaatgaggaagcctttctaagtgataag
gaattgatttcagatcatgaggacatggcagcttgcctagaagaggctagcgatcaagaa
gaggacagtataatcccggactcagtggcgtctggatatgagagtgaagcaaacctctct
gaagactgctcacagagtgatattctaaccactcagcagagggcgaccatgaaggataac
ctgataaagctccagcaggaaatggctcagctggaagctgtgctagagcagcatgggagc
cagccgtctggccaccccccttgcctcccagctgacccttgtgccctagaagacctgcca
gatccagaacaaaacagatcaggaacagcaattttaacttcaaagaacattaatgagaat
cctgtaagccagaatccaaagcgcgcctgtgatgacaaatcccaaccacaacctccggac
ggtctccccagtggagataaggagtcaggaatgagaaggccttccccttttaaatctcca
ctgaccagcagaaggtgctctgcacgaggccactccaggagtcttcagaatagaaactcc
acctctcaagaggagctccttcagcctgttgaattggagaagtcatgtgaaccacacaac
ttaacagggcggtcttgcttgccaaggcaagatctcgaaggaaccccatacctggaatct
ggaatcagccttttctccagtagagaccccgattctgaatcccctaaagtgccagccctt
gtttgcactgcaccagcttcaacctctgcactgaaaatatcccaaggtcaagttgctggg
tcttgcaggagtccagctgctggtggtgctgatactgcagtggtagaaattgtgagcaag
ataaagccggaagtgacgtcttcaaaagaacgagcggagagagatatatccatggtggtg
tcaggcttgacccctaaagaagtaatgattgtgcaaaagtttgctgaaaaataccgcctt
gctttaactgatgtaattactgaggaaactacgcatgtaattataaaaacagatgctgag
tttgtgtgtgaacggacactgaaatattttctgggcattgcaggaggaaagtggatagtt
agctattcttgggtgatcaagtctatccaagaaagaaaacttctgagtgtgcatgaattt
gaagtcaaaggagacgttgtgactggaagcaaccaccaaggtccaaggcgatccagagaa
tcccaggaaaagctctttgaaggcctacagatctattgttgtgagcccttcaccaacatg
cccaaagatgagctggagaggatgctgcagctgtgtggggcttctgtggtgaaggagctt
ccattgctcacccgtgacacaggtgctcatccaattgtgctcgtgcagccaagtgcctgg
acagaagacaacgactgccctgatattgggcagctgtgcaagggacgtctagtgatgtgg
gactgggtgttggacagtatatccgtctaccggtgtcgggatctggatgcctacctggta
cagaatatcacctgtggccgtgatggtagcgagccacaagactccaatgattaa
DBGET
integrated database retrieval system
