Rattus norvegicus (rat): 497811
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Entry
497811 CDS
T01003
Symbol
Xdh
Name
(RefSeq) xanthine dehydrogenase/oxidase
KO
K00106
xanthine dehydrogenase/oxidase [EC:
1.17.1.4
1.17.3.2
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00230
Purine metabolism
rno00232
Caffeine metabolism
rno00983
Drug metabolism - other enzymes
rno01100
Metabolic pathways
rno01232
Nucleotide metabolism
rno04146
Peroxisome
Module
rno_M00958
Adenine ribonucleotide degradation, AMP => Urate
rno_M00959
Guanine ribonucleotide degradation, GMP => Urate
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
497811 (Xdh)
09110 Biosynthesis of other secondary metabolites
00232 Caffeine metabolism
497811 (Xdh)
09111 Xenobiotics biodegradation and metabolism
00983 Drug metabolism - other enzymes
497811 (Xdh)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
497811 (Xdh)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
rno04147
]
497811 (Xdh)
Enzymes [BR:
rno01000
]
1. Oxidoreductases
1.17 Acting on CH or CH2 groups
1.17.1 With NAD+ or NADP+ as acceptor
1.17.1.4 xanthine dehydrogenase
497811 (Xdh)
1.17.3 With oxygen as acceptor
1.17.3.2 xanthine oxidase
497811 (Xdh)
Exosome [BR:
rno04147
]
Exosomal proteins
Exosomal proteins of breast milk
497811 (Xdh)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MoCoBD_2
MoCoBD_1
FAD_binding_5
Ald_Xan_dh_C
Fer2_2
CO_deh_flav_C
Fer2
Motif
Other DBs
NCBI-GeneID:
497811
NCBI-ProteinID:
NP_058850
RGD:
62043
Ensembl:
ENSRNOG00000007081
UniProt:
P22985
A6H9Z6
F1LQS6
Structure
PDB
PDBj
LinkDB
All DBs
Position
6:27282319..27344022
Genome browser
AA seq
1331 aa
AA seq
DB search
MTADELVFFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYDR
LQNKIVHFSVNACLAPICSLHHVAVTTVEGIGNTQKLHPVQERIARSHGSQCGFCTPGIV
MSMYTLLRNQPEPTVEEIENAFQGNLCRCTGYRPILQGFRTFAKDGGCCGGSGNNPNCCM
NQTKDQTVSLSPSLFNPEDFKPLDPTQEPIFPPELLRLKDTPQKKLRFEGERVTWIQAST
MEELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIVCPAWIPELNSVVHGPEGISFGA
SCPLSLVESVLAEEIAKLPEQKTEVFRGVMEQLRWFAGKQVKSVASIGGNIITASPISDL
NPVFMASGAKLTLVSRGTRRTVRMDHTFFPGYRKTLLRPEEILLSIEIPYSKEGEFFSAF
KQASRREDDIAKVTSGMRVLFKPGTIEVQELSLCFGGMADRTISALKTTPKQLSKSWNEE
LLQSVCAGLAEELHLAPDAPGGMVEFRRTLTLSFFFKFYLTVLQKLGRADLEDMCGKLDP
TFASATLLFQKDPPANVQLFQEVPKDQSEEDMVGRPLPHLAANMQASGEAVYCDDIPRYE
NELSLRLVTSTRAHAKITSIDTSEAKKVPGFVCFLTAEDVPNSNATGLFNDETVFAKDEV
TCVGHIIGAVVADTPEHAQRAARGVKITYEDLPAIITIQDAINNNSFYGSEIKIEKGDLK
KGFSEADNVVSGELYIGGQEHFYLETNCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKML
GVPDNRIVVRVKRMGGGFGGKETRSTVVSTAVALAAHKTGRPVRCMLDRDEDMLITGGRH
PFLAKYKVGFMKTGTVVALEVAHFSNGGNTEDLSRSIMERALFHMDNAYKIPNIRGTGRI
CKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAITCGLPAEEVRRKNMYKEGDLTHFNQKLE
GFTLPRCWDECIASSQYLARKREVEKFNRENCWKKRGLCIIPTKFGISFTLPFLNQGGAL
VHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIHISETSTNTVPNTSPTAAS
ASADLNGQAVYEACQTILKRLEPFKKKKPNGPWEAWVMDAYTSAVSLSATGFYKTPNLGY
SFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFV
QGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKRAIYASKAVG
EPPLFLASSIFFAIKDAIRAARAQHGDNAKQLFQLDSPATPEKIRNACVDQFTTLCVTGV
PENCKSWSVRI
NT seq
3996 nt
NT seq
+upstream
nt +downstream
nt
atgactgcggatgagttggtcttctttgtgaatggcaaaaaggtggtggagaaaaatgcg
gaccctgaaacaacacttctggtctacctgagaagaaagttggggctatgtgggaccaag
cttggctgtggagaaggtggctgtggggcatgcaccgtgatgatctccaagtatgaccgt
cttcagaacaagattgttcatttttctgtcaatgcctgcttggctcccatctgctccttg
caccatgttgctgtgaccaccgtggaaggcataggaaacacccagaagctgcatcctgta
caggagagaattgccagaagccatggttcccagtgtgggttctgcactcctggcattgtc
atgagtatgtacacactgctccggaaccagcctgagcctactgttgaggagatcgagaat
gccttccaaggaaacctctgtcgctgtacaggctacagacccatcctccagggattccgg
acctttgccaaggatggtgggtgctgtggagggagtggaaacaacccaaactgctgtatg
aaccagacgaaagaccaaacggtttctctctcaccttctttattcaacccagaggatttc
aaacctttagatcccacgcaagagcccatcttccccccagagttgctgaggctgaaagac
actccccagaagaagctgcgttttgaaggggaacgtgtgacctggatccaggcttcaact
atggaggagctgcttgacctgaaagctcagcaccctgatgccaagctggtggtgggaaac
acagagataggcattgaaatgaaatttaagaatatgctatttcctctgatcgtctgccca
gcctggatccctgaactgaattcagtggtgcatgggcctgagggaatctccttcggagct
tcttgcccccttagcttggtggaaagtgtcctggcggaggagattgctaaacttccagag
caaaagacagaggtgttcagaggcgtgatggagcagctgcgctggtttgccggcaagcag
gtcaagtccgtggcgtccatcggagggaacatcatcactgccagccccatctctgacctc
aaccctgtgttcatggccagtggagccaagctgactctggtgtctagaggtaccaggaga
actgttcggatggatcataccttcttccctggctacagaaagactctgctcagaccagag
gagatattgctgtccatcgagatcccctatagcaaggagggagagtttttctcagccttc
aagcaggcctccaggagggaagatgacattgccaaggtgactagtggcatgagagtcctg
ttcaaaccggggaccattgaagtgcaggaactgtccctttgcttcggagggatggccgac
agaactatctcagccctcaagaccactccgaagcagctatcgaagtcctggaatgaggag
ctgctgcagagcgtgtgtgccggcttggcagaggagctgcacctggcccccgatgcccct
ggtggtatggtggaattccggcgcaccctcaccctcagcttcttcttcaagttctacctg
acagtgctccagaagctgggcagagcggaccttgaggatatgtgtggtaaactggacccc
acctttgccagtgccaccctgctctttcagaaggaccctccagctaatgtccagcttttc
caagaggtgccaaaggatcagtctgaggaggacatggtgggccggcccctgcctcacctg
gcggcaaacatgcaggcatcgggagaggccgtgtactgtgatgacattccccgctatgag
aatgagctctctctcaggctggtcaccagcacccgggcgcatgctaaaatcacgtccatc
gacacttcagaagccaagaaggtgccagggtttgtttgcttcctcaccgcagaggatgtc
cctaatagtaatgcaaccggccttttcaatgatgaaactgtctttgcgaaggatgaggtt
acttgtgttgggcacatcattggtgctgtggtcgctgacaccccagaacacgcacagaga
gctgcgagaggggtgaaaatcacctatgaagatcttccagccattatcacaatccaggat
gctataaacaacaactccttttatggctctgagataaaaattgagaaaggagatctcaag
aaaggcttttcagaagctgacaatgttgtctcaggagagttgtatatcggtggccaggag
cacttctacctggagaccaactgcaccattgccgtgccaaaaggcgaggcaggcgagatg
gagctgttcgtgagcacacagaacaccatgaaaacccagagctttgttgcaaaaatgttg
ggcgttccggacaacagaatcgtagtccgagtgaagaggatgggtggaggctttggaggg
aaggagacccggagcactgtggtgtccacagcagtggccttggctgcacacaagactggc
cggcccgtacgttgcatgttggaccgagatgaggacatgctgataactggtggcagacat
cccttcctggctaaatacaaggttggcttcatgaagactgggactgtagtggctctcgag
gtggctcacttcagcaatggtggtaacactgaggatctctctcggagtataatggaacga
gctttgttccacatggataacgcctataagatccccaacattcgaggcactgggaggatt
tgcaagactaatctgccctccaacacagccttcagaggttttgggggtcctcaggggatg
ctaatcgcagaatactggatgagcgaggtcgccataacctgtgggctgcctgcagaggag
gtacggaggaaaaacatgtacaaagaaggggacctgactcacttcaaccagaagctggag
gggttcaccttgcccaggtgctgggatgaatgcatcgccagctctcagtatcttgctcgc
aagagggaagtggagaaattcaacagggagaattgttggaaaaagagagggctgtgtata
atcccaactaagtttggaataagctttacacttccttttctgaaccagggaggcgctctg
gttcacgtgtacactgatggttcggtgctgttgacccatggagggactgagatgggccaa
ggccttcacaccaagatggttcaggtggccagcagagctctgaaaatccccacctccaag
attcatataagtgagacaagcactaacaccgtccccaacacttctcccacagctgcctct
gccagtgctgacctcaatggacaggctgtttatgaagcatgccagaccatactgaaaagg
ctggaacctttcaagaagaagaaacccaacggcccctgggaggcatgggtgatggacgcc
tatacgagcgcagtgagtttgtccgcgactggattttataagacacccaaccttggctac
agctttgagacaaactccggaaatcccttccactatttcagttatggggtggcttgctct
gaagtagaaattgactgcttaacaggggatcataagaatctccgtacggatatcgtcatg
gatgttggttccagcttgaatcctgccattgatattggacaagtagagggggcatttgtc
cagggccttggtctcttcactatggaggagctgcactactcccctgaggggagcctgcat
actcgtggccccagtacctacaaaatccctgcgtttggtagcatccccattgagttcaga
gtatccctactccgggactgccccaacaagagggccatctatgcatccaaggctgttggg
gagccacctcttttcctggcttcctctatcttctttgccatcaaagatgccattcgtgca
gctcgagctcagcacggagataacgcaaaacaacttttccagctagacagccctgccact
ccggagaagatccgaaacgcctgtgtggaccagttcaccaccctgtgtgtcactggagta
ccagaaaactgtaaatcctggtctgtgaggatctga
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