KEGG   Rattus norvegicus (rat): 54287
Entry
54287             CDS       T01003                                 
Symbol
Eif2ak2
Name
(RefSeq) interferon-induced, double-stranded RNA-activated protein kinase
  KO
K16195  eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04217  Necroptosis
rno05010  Alzheimer disease
rno05160  Hepatitis C
rno05162  Measles
rno05164  Influenza A
rno05165  Human papillomavirus infection
rno05167  Kaposi sarcoma-associated herpesvirus infection
rno05168  Herpes simplex virus 1 infection
rno05169  Epstein-Barr virus infection
rno05171  Coronavirus disease - COVID-19
rno05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    54287 (Eif2ak2)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    54287 (Eif2ak2)
  09172 Infectious disease: viral
   05160 Hepatitis C
    54287 (Eif2ak2)
   05171 Coronavirus disease - COVID-19
    54287 (Eif2ak2)
   05164 Influenza A
    54287 (Eif2ak2)
   05162 Measles
    54287 (Eif2ak2)
   05168 Herpes simplex virus 1 infection
    54287 (Eif2ak2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    54287 (Eif2ak2)
   05169 Epstein-Barr virus infection
    54287 (Eif2ak2)
   05165 Human papillomavirus infection
    54287 (Eif2ak2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    54287 (Eif2ak2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    54287 (Eif2ak2)
   01009 Protein phosphatases and associated proteins [BR:rno01009]
    54287 (Eif2ak2)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:rno03019]
    54287 (Eif2ak2)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     54287 (Eif2ak2)
Protein kinases [BR:rno01001]
 Serine/threonine kinases: Other
  PEK family [OT]
   54287 (Eif2ak2)
Protein phosphatases and associated proteins [BR:rno01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     54287 (Eif2ak2)
Messenger RNA biogenesis [BR:rno03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    P-body specific factors
     54287 (Eif2ak2)
SSDB
Motif
Pfam: Pkinase dsrm PK_Tyr_Ser-Thr DSRM_2 ABC1 Pkinase_fungal Kinase-like FTA2 DND1_DSRM RIO1 Kdo SR-25
Other DBs
NCBI-GeneID: 54287
NCBI-ProteinID: NP_062208
RGD: 3402
Ensembl: ENSRNOG00000048315
UniProt: Q63184 A0A0G2K100 A6H9V3
LinkDB
Position
6:21941147..21977115
AA seq 513 aa
MASDTPGFYVDKLNKYSQIHKVKIIYKEISVTGPPHDRRFTFQVIIEEREFPEGEGRSKQ
EAKNNAAKLAVEILDNENKVDSHTDASEQGLIEGNYIGLVNSFAQKENLPVNFELCDPDS
QLPHRFICKCKIGQTTYGTGFGANKKEAKQLAAKNAYQKLSEKSPSKTGFVTSLSSDFSS
SSSITSNSASQSASGRDFEDIFMNGLREKRKSGVKVPSDDVLRNKYTLDDRFSKDFEDIE
EIGSGGFGQVFKAKHRIDGKTYAIKRITYNTKKAKREVQALAELNHANIVQYRVCWEGED
YDYDPENSTNGDTSRYKTRCLFIQMEFCDKGTLQQWLEKRNRSQEDKALVLELFEQIVTG
VDYIHSKGLIHRDLKPGNIFLVDEKHIKIGDFGLATALENDGNPRTKYTGTPQYMSPEQK
SSLVEYGKEVDIFALGLILAELLHICKTDSEKIEFFQLLRNGVFSDDIFDNKEKSLLQKL
LSSKPRERPNTSEILKTLAEWKNISEKKKRNTC
NT seq 1542 nt   +upstreamnt  +downstreamnt
atggccagtgatacaccaggtttctacgtggacaaacttaacaaatactcccagatacac
aaagtaaagattatatataaagaaatttctgttacaggacctccacacgacagaaggttt
acatttcaagttataatagaagagagggaatttccagaaggtgaaggtagatcaaagcag
gaggcgaaaaataatgctgccaaattagctgtcgaaatacttgataatgaaaacaaggtg
gatagtcacacggatgcttctgaacaaggtttaatagaggggaactacattggccttgtc
aattcttttgcccagaaggaaaatctgcctgtaaattttgaactgtgtgaccccgactcc
caattgcctcacagatttatttgtaaatgcaaaatcgggcagactacgtatggtactggt
tttggcgctaacaaaaaggaggcaaagcagttggctgccaaaaatgcgtatcagaagctg
tcagagaaaagcccatcgaaaactggctttgtcacatctttatccagtgacttttccagc
agctcgtctataacaagtaactctgcttctcagtcagcatctggaagggatttcgaggac
atatttatgaatggtctcagagaaaaaaggaaatcaggagtaaaagtgccatctgatgac
gtgctaagaaataaatataccttggacgacaggtttagcaaagattttgaagacatagaa
gaaattggctcgggtggatttggccaagttttcaaagcaaaacacagaatcgatggaaag
acgtatgctattaagcgcattacatataacaccaagaaggcaaagcgtgaagtacaagca
ctagcagaactcaatcacgccaacattgttcaataccgagtttgttgggagggagaggac
tatgactatgatcccgagaacagcacaaacggtgacacaagtcgatacaagacccggtgc
ctctttatccaaatggaattctgtgataaaggaactctgcagcagtggttggaaaagaga
aatcggagtcaagaggacaaggctttggttttggagttatttgaacaaatagtgacagga
gtggattatatacactcgaaaggtttaattcatagagaccttaagccaggtaatatattt
ttagtggatgaaaaacacattaagatcggagactttggccttgcaacagccctggaaaat
gatggaaatcctcgaacaaagtatacaggaactcctcaatacatgagtccagaacaaaag
tcatcgttagtggaatatggaaaggaagtggacatctttgctttgggccttattctagct
gaacttcttcacatatgcaaaactgattcagagaaaatagagtttttccaacttctaaga
aatggcgtcttctccgatgatattttcgacaacaaggaaaaaagtcttctacagaaatta
ctctcaagtaaacccagggaacgacccaatacgtctgaaatcctgaagactttggctgag
tggaagaacatctcggagaaaaagaaaagaaacacgtgttag

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