Rattus norvegicus (rat): 59086
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Entry
59086 CDS
T01003
Symbol
Tgfb1
Name
(RefSeq) transforming growth factor beta-1 proprotein precursor
KO
K13375
transforming growth factor beta-1
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04010
MAPK signaling pathway
rno04060
Cytokine-cytokine receptor interaction
rno04068
FoxO signaling pathway
rno04110
Cell cycle
rno04148
Efferocytosis
rno04218
Cellular senescence
rno04350
TGF-beta signaling pathway
rno04380
Osteoclast differentiation
rno04390
Hippo signaling pathway
rno04518
Integrin signaling
rno04659
Th17 cell differentiation
rno04672
Intestinal immune network for IgA production
rno04926
Relaxin signaling pathway
rno04932
Non-alcoholic fatty liver disease
rno04933
AGE-RAGE signaling pathway in diabetic complications
rno05140
Leishmaniasis
rno05142
Chagas disease
rno05144
Malaria
rno05145
Toxoplasmosis
rno05146
Amoebiasis
rno05152
Tuberculosis
rno05161
Hepatitis B
rno05166
Human T-cell leukemia virus 1 infection
rno05200
Pathways in cancer
rno05205
Proteoglycans in cancer
rno05210
Colorectal cancer
rno05211
Renal cell carcinoma
rno05212
Pancreatic cancer
rno05220
Chronic myeloid leukemia
rno05225
Hepatocellular carcinoma
rno05226
Gastric cancer
rno05321
Inflammatory bowel disease
rno05323
Rheumatoid arthritis
rno05410
Hypertrophic cardiomyopathy
rno05414
Dilated cardiomyopathy
rno05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
59086 (Tgfb1)
04350 TGF-beta signaling pathway
59086 (Tgfb1)
04390 Hippo signaling pathway
59086 (Tgfb1)
04068 FoxO signaling pathway
59086 (Tgfb1)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
59086 (Tgfb1)
04518 Integrin signaling
59086 (Tgfb1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
59086 (Tgfb1)
09143 Cell growth and death
04110 Cell cycle
59086 (Tgfb1)
04218 Cellular senescence
59086 (Tgfb1)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
59086 (Tgfb1)
04672 Intestinal immune network for IgA production
59086 (Tgfb1)
09152 Endocrine system
04926 Relaxin signaling pathway
59086 (Tgfb1)
09158 Development and regeneration
04380 Osteoclast differentiation
59086 (Tgfb1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
59086 (Tgfb1)
05205 Proteoglycans in cancer
59086 (Tgfb1)
09162 Cancer: specific types
05210 Colorectal cancer
59086 (Tgfb1)
05212 Pancreatic cancer
59086 (Tgfb1)
05225 Hepatocellular carcinoma
59086 (Tgfb1)
05226 Gastric cancer
59086 (Tgfb1)
05220 Chronic myeloid leukemia
59086 (Tgfb1)
05211 Renal cell carcinoma
59086 (Tgfb1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
59086 (Tgfb1)
05161 Hepatitis B
59086 (Tgfb1)
09171 Infectious disease: bacterial
05152 Tuberculosis
59086 (Tgfb1)
09174 Infectious disease: parasitic
05146 Amoebiasis
59086 (Tgfb1)
05144 Malaria
59086 (Tgfb1)
05145 Toxoplasmosis
59086 (Tgfb1)
05140 Leishmaniasis
59086 (Tgfb1)
05142 Chagas disease
59086 (Tgfb1)
09163 Immune disease
05323 Rheumatoid arthritis
59086 (Tgfb1)
05321 Inflammatory bowel disease
59086 (Tgfb1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
59086 (Tgfb1)
05414 Dilated cardiomyopathy
59086 (Tgfb1)
05415 Diabetic cardiomyopathy
59086 (Tgfb1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
59086 (Tgfb1)
04933 AGE-RAGE signaling pathway in diabetic complications
59086 (Tgfb1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
rno03110
]
59086 (Tgfb1)
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides [BR:
rno04052
]
59086 (Tgfb1)
00536 Glycosaminoglycan binding proteins [BR:
rno00536
]
59086 (Tgfb1)
Chaperones and folding catalysts [BR:
rno03110
]
Intramolecular chaperones
Others
59086 (Tgfb1)
Cytokines and neuropeptides [BR:
rno04052
]
Cytokines
Transforming growth factors (RSTK binding)
59086 (Tgfb1)
Glycosaminoglycan binding proteins [BR:
rno00536
]
Heparan sulfate / Heparin
Growth factors/receptors
59086 (Tgfb1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
TGFb_propeptide
TGF_beta
CBM96
Motif
Other DBs
NCBI-GeneID:
59086
NCBI-ProteinID:
NP_067589
RGD:
69051
Ensembl:
ENSRNOG00000020652
UniProt:
P17246
A6J986
LinkDB
All DBs
Position
1:90324312..90340627
Genome browser
AA seq
390 aa
AA seq
DB search
MPPSGLRLLPLLLPLPWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA
SPPSQGEVPPGPLPEAVLALYNSTRDRVAGESADPEPEPEADYYAKEVTRVLMVDRNNAI
YDKTKDITHSIYMFFNTSDIREAVPEPPLLSRAELRLQRFKSTVEQHVELYQKYSNNSWR
YLGNRLLTPTDTPEWLSFDVTGVVRQWLNQGDGIQGFRFSAHCSCDSKDNVLHVEINGIS
PKRRGDLGTIHDMNRPFLLLMATPLERAQHLHSSRHRRALDTNYCFSSTEKNCCVRQLYI
DFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASASPCCVPQA
LEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgccgccctcggggctgcggctgctgccgcttctgctcccactcccgtggcttctagtg
ctgacgcccgggaggccagccgcgggactctccacctgcaagaccatcgacatggagctg
gtgaaacggaagcgcatcgaagccatccgtggccagatcctgtccaaactaaggctcgcc
agtcccccgagccagggggaggtaccgccgggcccgctgcccgaggcggtgctcgctttg
tacaacagcacccgcgaccgggtggcaggcgagagcgctgacccggagcccgagcccgag
gcggactactacgccaaagaagtcacccgcgtgctaatggtggaccgcaacaacgcaatc
tatgacaaaaccaaagacatcacacacagtatatatatgttcttcaatacgtcagacatt
cgggaagcagtgccagaacccccattgctgtcccgtgcagagctgcgcctgcagagattc
aagtcaactgtggagcaacacgtagaactctaccagaaatatagcaacaattcctggcgt
taccttggtaaccggctgctgacccccactgatacgcctgagtggctgtcttttgacgtc
actggagttgtccggcagtggctgaaccaaggagacggaatacagggctttcgcttcagt
gctcactgctcttgtgacagcaaagataatgtactccacgtggaaatcaatgggatcagt
cccaaacgtcgaggtgacctgggcaccatccatgacatgaaccgacccttcctgctcctc
atggccacccccctggaaagggctcaacacctgcacagctccaggcaccggagagccctg
gataccaactactgcttcagctccacagagaagaactgctgtgtacggcagctgtacatt
gactttaggaaggacctgggttggaagtggatccacgagcccaagggctaccatgccaac
ttctgtctggggccctgcccctacatttggagcctggacacacagtacagcaaggtcctt
gccctctacaaccaacacaacccgggtgcttccgcatcaccgtgctgcgtgccgcaggct
ttggagccactgcccatcgtctactacgtgggtcgcaagcccaaggtggagcagttgtcc
aacatgatcgtgcgctcctgcaagtgcagctga
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