Rattus norvegicus (rat): 60323
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Entry
60323 CDS
T01003
Symbol
Arhgef1
Name
(RefSeq) rho guanine nucleotide exchange factor 1
KO
K12330
Rho guanine nucleotide exchange factor 1
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04270
Vascular smooth muscle contraction
rno04611
Platelet activation
rno04810
Regulation of actin cytoskeleton
rno04928
Parathyroid hormone synthesis, secretion and action
rno05135
Yersinia infection
rno05163
Human cytomegalovirus infection
rno05200
Pathways in cancer
rno05205
Proteoglycans in cancer
rno05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
60323 (Arhgef1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
60323 (Arhgef1)
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
60323 (Arhgef1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
60323 (Arhgef1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
60323 (Arhgef1)
05205 Proteoglycans in cancer
60323 (Arhgef1)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
60323 (Arhgef1)
09171 Infectious disease: bacterial
05135 Yersinia infection
60323 (Arhgef1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
60323 (Arhgef1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
rno04131
]
60323 (Arhgef1)
Membrane trafficking [BR:
rno04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
60323 (Arhgef1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RGS-like
PH_16
RhoGEF
PH_13
AbiJ_NTD3
SOS1_NGEF_PH
SET_assoc
Motif
Other DBs
NCBI-GeneID:
60323
NCBI-ProteinID:
NP_067726
RGD:
620951
Ensembl:
ENSRNOG00000020130
UniProt:
Q5BK37
LinkDB
All DBs
Position
1:89626884..89648823
Genome browser
AA seq
919 aa
AA seq
DB search
MGEVAGGAAPGPPRSGLVSIIIGAEDEDFENELEANPEDQNSQFQSLEQVKRRPAHLMAL
LQHVALQFEPGPLLCCLHADMLSSLGPKEAKKAFLDFYHSFLEKTAVLRVPVPPSVAFEL
DRTRPDLISEDVQRRFIQEVVQSQQAAVTRQLEDFRSKRLMGMTPWEQELSLLEPWIGKD
RGNYEARERHVAERLLSHLEEMQHTISTDEEKSAAVVTAISLYMRHLGVRTKSGDKKSGR
NFFRKKVMGNRRSDEPPKTKKGLSSILDPARWNRGEPSAPDCRHLKVEVDEKPGPADRKG
SLGISSRDRTVGTPGQDNPGVSLHPLSVDSLDSREPGVDTPQEPGDTPPQGPTSLEPLAP
PESTEDNGETESPEPGDDGEPGRSGLEQEPEEPPGWRELVPSDTLLGLPKNQVKRQEVIS
ELLVTEAAHVRMLRVLHDLFYQPMAEGGFFPLEELQNIFPSLDELIEVHSLFLDRLMKRR
QESGYLIEEIGDVLLARFDGAEGSWFQKISSRFCSRQSFALEQLKAKQRKEPRFCAFVQE
AESRPRCRRLQLKDMIPTEMQRLTKYPLLLQSIGQNTEEPAERAKVELAAECCREILHHV
NQAVRDMEDLLRLKDYQRRLDLTHLRQSNDPMLSEFKNLDITKKKLVHEGPLTWRLTKDK
AVEVHVLLLDDLLLLLQRQDERLLLKSHSRTLTPTPDGKTMLRPVLRLTSAMTREVATDH
KAFYVIFTWDQEAQIYELVAQTSSERKSWCALITETAGSLKVPAPASRPKPRPSPSSTRE
PLLSSSENGTGGTEAAPADARTERILNDLLPFCRPGPEGQLAATALQKVLSLKQILLSTE
EDSGAGPPRDGDGVPGGGAPGPTHTQEVEENLLSLEVVIKQLEELEEEFCRLRPFLSQLG
EILSPNLAAPERSAQTGLS
NT seq
2760 nt
NT seq
+upstream
nt +downstream
nt
atgggagaagtcgccggaggggcggccccagggcctccccggtctggcctggtgtccatc
atcatcggggctgaggatgaggactttgagaatgaactggaggcgaacccagaagatcaa
aacagccagttccagagcctggagcaagtgaagcgtcgcccagcccacctcatggccctc
ctgcaacacgtggccctgcagttcgagccaggaccactgctctgctgcctgcatgctgac
atgctaagctcactgggccccaaagaagccaagaaggccttcctcgatttctatcacagt
ttcctggagaagactgcggttctgcgggtgccggtccctcccagcgttgcttttgaactt
gatcgtactcggcctgatctcatctctgaggatgtccagaggcggttcatacaagaggtg
gtacagagccagcaggcagccgtgacccgtcagctagaggacttccgctccaaacggctc
atgggcatgacaccctgggagcaggaactgagcctgctagagccctggattgggaaagac
cggggcaactatgaggcccgggagcggcatgttgcagagcggctgctctcccacctagag
gaaatgcaacataccatctccacagatgaagaaaaaagtgctgctgtggtcactgcaatc
agcctgtatatgcgccaccttggggtccggaccaagagtggggacaagaagtcagggagg
aacttcttccggaaaaaggtgatggggaatcggcggtcagacgagccccccaagacaaag
aaagggctgagcagtatcctagatcctgcccgctggaaccggggagagccatctgctcca
gactgtcgacatctaaaggtcgaggttgatgagaagccaggccctgcagaccggaaggga
agcctgggtatttcatctcgggacaggactgttgggactcctgggcaggacaacccagga
gtctccctgcaccctctgtctgtagacagcctggattcccgggaaccaggtgtggatacc
ccgcaggagccaggagatacacccccacaaggccctacaagcctggagcccctggcaccc
ccagagagcacagaggacaatggcgagactgaaagccctgagcctggagatgatggagag
ccagggcggtcaggcctggaacaggaaccagaagaacctcctgggtggagggaactggtg
ccctcagacaccctgctcggcctgcccaagaaccaagtgaagcggcaagaggtcatcagt
gagctgctggtgacggaggcggctcacgtccgcatgctacgggtactacatgacctcttc
taccagcccatggcagaagggggcttcttccctctggaggaactgcagaacatctttccc
agcctggatgagctcatcgaggtgcactccctgttcctcgatcgcttgatgaagcggaga
caagagagtggctacctcattgaggagattggtgatgtgctactggcccggttcgatggt
gctgagggctcatggttccagaagatctcttcccgcttctgcagccgccagtcattcgct
ctagagcagctcaaagccaagcagcgcaaggagcctcgattctgtgcctttgtgcaggaa
gctgagagccgcccccgctgccggcggctgcagttgaaggacatgatccccactgagatg
cagcggctgaccaagtacccactgctgctgcagagtattgggcagaacacagaagagcct
gccgagcgggcaaaggtggaacttgcagctgagtgctgccgtgagattctgcaccacgtt
aatcaagctgtccgtgacatggaggacctgctgcggctcaaggattaccagcggcgcctg
gacttgactcacctgcggcagagcaatgacccaatgctgagcgagttcaagaacctggat
atcactaagaagaagttggtccatgaaggccccctcacgtggcgactaaccaaagacaaa
gctgtagaggtccacgtgctattgctggacgacctgctgctgctgctccagcgccaggat
gagaggctgctgctcaagtcacacagccggacgctgacacccacacccgacggcaagacc
atgctgcggcctgtgctccggctcacctctgccatgacccgggaggtggccactgatcac
aaagctttttacgtcatttttacctgggaccaggaggcccagatatatgagctggtggca
cagacatcgtcggaacgcaagagctggtgtgccctcatcacagagactgccggatccctg
aaggtccctgcccctgcctcccgccccaaaccccggcccagcccaagcagcacccgagaa
cccctgctcagcagctctgagaatggcactggaggcacagaggccgctccagctgatgcc
cggacagagcggatcctcaacgacctcctgcccttctgcagaccaggcccagagggccag
cttgctgccacagccctccagaaagtactgtccctgaaacagatcctgttgagcactgag
gaagacagtggagcagggcctccccgcgatggggatggggtgcctggtggtggtgcccca
ggcccaacacacacccaggaggttgaggaaaacctgttgagcctagaagtggtcatcaaa
caactggaggagttagaagaggaattttgtcgcctaagacccttcctgtctcagcttggg
gagattctgtcccccaacctggctgcacctgagcgctctgctcagacaggcctttcatga
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