KEGG   Rattus norvegicus (rat): 690050
Entry
690050            CDS       T01003                                 
Symbol
Tpmt
Name
(RefSeq) thiopurine S-methyltransferase
  KO
K00569  thiopurine S-methyltransferase [EC:2.1.1.67]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00983  Drug metabolism - other enzymes
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    690050 (Tpmt)
Enzymes [BR:rno01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.67  thiopurine S-methyltransferase
     690050 (Tpmt)
SSDB
Motif
Pfam: TPMT Methyltransf_25 Methyltransf_11
Other DBs
NCBI-GeneID: 690050
NCBI-ProteinID: NP_001382599
RGD: 1585162
Ensembl: ENSRNOG00000016468
UniProt: Q9Z0T0 B0BMT6
LinkDB
Position
17:17850308..17868976
AA seq 240 aa
MSLGIKEHPDAEVQKNRVLTLDDWQDKWVTRHIAFHQEQGHQLLKKHFDTFLKGQSGLRV
FFPLCGKAIEMKWFADRGHTVVGVEISEIGIREFFAEQNLSYTEEPLTEIAGAKVFKSSS
GNISLYCCSIFDLPRANIGKFDRIWDRGALVAVNPGDRDRYADIILSLLRKGYHYLLVVL
SYDPTKHTGPPFYVPDAELKKLFGTKCNMQCLEEVDALEERHKTWGVDYFFEKLYLLTEK
NT seq 723 nt   +upstreamnt  +downstreamnt
atgtcactcggtatcaaagagcaccctgatgctgaggtacaaaagaaccgggtactaacc
ctggacgactggcaagacaagtgggtgacccgtcacatcgcattccatcaggagcaaggg
catcagctattaaagaagcatttcgatacatttcttaaagggcagagtggactgagagtg
tttttcccgctctgtggaaaagccattgagatgaaatggttcgcagaccggggccacact
gtagttggtgtagaaatcagtgaaattgggattcgggaattttttgcagaacagaatctg
tcatacacagaagaaccgctcaccgaaattgctggtgccaaagtgtttaagagttcttcc
gggaacatttccttatactgttgcagcattttcgaccttcccagagcaaacatcggcaag
tttgacaggatttgggatagaggagcattggtggctgtcaatccaggcgatcgtgaccgc
tatgcagatataatactgtccctgctgagaaaagggtatcactacctcctggttgtcctt
tcttatgatccaacaaaacacacaggcccgccattttatgttccagatgctgaacttaaa
aagttatttggtacaaaatgcaacatgcaatgccttgaggaggtggatgctcttgaagaa
aggcataaaacctggggagtcgactactttttcgaaaaattgtatctccttactgagaag
tag

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