Rattus norvegicus (rat): 690743
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Entry
690743 CDS
T01003
Symbol
Mlkl
Name
(RefSeq) mixed lineage kinase domain-like protein
KO
K08849
mixed lineage kinase domain-like [EC:
2.7.11.1
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04217
Necroptosis
rno04623
Cytosolic DNA-sensing pathway
rno04668
TNF signaling pathway
rno05132
Salmonella infection
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04668 TNF signaling pathway
690743 (Mlkl)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
690743 (Mlkl)
09150 Organismal Systems
09151 Immune system
04623 Cytosolic DNA-sensing pathway
690743 (Mlkl)
09160 Human Diseases
09171 Infectious disease: bacterial
05132 Salmonella infection
690743 (Mlkl)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rno01001
]
690743 (Mlkl)
Enzymes [BR:
rno01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
690743 (Mlkl)
Protein kinases [BR:
rno01001
]
Serine/threonine kinases: TKL group
Other
690743 (Mlkl)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MLKL_N
PK_Tyr_Ser-Thr
Pkinase
Kinase-like
DUF7792
COG7
Motif
Other DBs
NCBI-GeneID:
690743
NCBI-ProteinID:
NP_001388006
RGD:
1592221
Ensembl:
ENSRNOG00000042353
UniProt:
A6IZ87
A0A8I5ZV82
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All DBs
Position
19:complement(56186860..56213886)
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AA seq
464 aa
AA seq
DB search
MDKLGQIIKLGQLIYDQCEKMKYCKRQCRRLRNRVHGLLQPLQRLQAQEKKSLPSDITAA
LGRFEDVLKEARQQIEKFSQKSNIWKFATVGSDKILFHEVNEKLRDIWEELLLLLQVDQW
KSDSEVSQPASWQQEDQQDAEEDGNENMKVILVKLQISMEEIKEALKQCSLKPMQEVPQD
FQVKEIPKEDLGYPWTKLKTNKLSTIYRGEYYKSPVTIKVFNNPKAESVGIVRLTFNEEI
KTMKKFDSPNILRIFGICIDQTVKPPEFSIVMEYCELGTLRELLDRDKDLTMSVRSLLVL
RAARGLYRLHHSGTLHGNISSSSFLVAGGYQVKLAGFELSKTQTSISRATKSTKAERFSS
TAYVSPERLQDPFCKYDTKAEIYSFGIVLWEIATGKIPFEGCDSEKIYELVAENKKQEPV
GQDCPELLQEIINECRAHEPSNRPSADGILERLPAIEDSMDKKL
NT seq
1395 nt
NT seq
+upstream
nt +downstream
nt
atggataaattgggacagatcatcaagttaggccagctcatctatgaccagtgtgaaaag
atgaaatactgcaaaagacagtgccggcgtctaagaaaccgtgtgcatggcctgctacag
cctctccagaggctccaggcccaagaaaagaagagcctccccagtgacattactgctgcc
ctgggccgttttgaggacgtcctaaaagaagctagacagcagatagaaaagttcagtcag
aagtccaatatttggaagtttgctactgtgggcagtgataagatcctcttccatgaagtg
aatgagaagctgagagacatctgggaggagctcttgctgctgcttcaggttgatcaatgg
aagtctgattccgaggtcagccaaccagcatcctggcagcaggaagatcaacaggacgca
gaggaagatggaaatgaaaatatgaaagttattttggtgaagctgcaaatcagcatggaa
gaaatcaaagaggccctgaagcaatgctcactaaaacccatgcaggaggtcccacaagat
ttccaagtcaaggagattccgaaggaagatcttggatatccgtggaccaaactgaagaca
aataaactgagcacgatttatagaggagagtattacaaatctccagtcaccatcaaagta
ttcaacaaccccaaggccgaaagtgttggaatagtgaggctcactttcaatgaggagatc
aaaaccatgaagaaatttgattctcccaacatcctgcgtatatttgggatttgcatcgat
caaacagtgaagccccccgaattctccattgtcatggagtactgtgaactcggaaccctg
agggaactgctggatagagacaaggacctcaccatgagtgtgcgcagcctcctagtcctg
agggcagctagaggcttgtacaggttacaccactcgggaacactccacggaaacatcagc
agctccagcttcctggtagctggaggctaccaagtaaagcttgcaggatttgagctaagc
aaaacacagacttctataagccgggcaacaaagagcactaaagcagagagattcagttcg
acagcatatgtctcccccgagagactgcaagatccattttgcaaatatgacacaaaagct
gaaatatatagctttggaattgtgctctgggaaattgccactggaaagatcccgtttgaa
ggctgtgattctgagaagatctatgagctggtggctgagaacaagaagcaggagccagtg
ggtcaggattgccccgagttgttgcaggagatcattaatgagtgccgggcccatgaaccc
tccaatcggccctctgcggatggaatcttggagagactgcctgccattgaagactccatg
gacaaaaagctgtaa
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