Rattus norvegicus (rat): 79244
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Entry
79244 CDS
T01003
Symbol
Hsd17b4
Name
(RefSeq) peroxisomal multifunctional enzyme type 2
KO
K12405
(3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.-
4.2.1.107
4.2.1.119
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00120
Primary bile acid biosynthesis
rno01040
Biosynthesis of unsaturated fatty acids
rno01100
Metabolic pathways
rno01212
Fatty acid metabolism
rno04146
Peroxisome
Module
rno_M00861
beta-Oxidation, peroxisome, VLCFA
rno_M00862
beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09103 Lipid metabolism
00120 Primary bile acid biosynthesis
79244 (Hsd17b4)
01040 Biosynthesis of unsaturated fatty acids
79244 (Hsd17b4)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
79244 (Hsd17b4)
Enzymes [BR:
rno01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.107 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase
79244 (Hsd17b4)
4.2.1.119 enoyl-CoA hydratase 2
79244 (Hsd17b4)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MFE-2_hydrat-2_N
MaoC_dehydratas
adh_short
adh_short_C2
SCP2
KR
Alkyl_sulf_C
FAS1_DH_region
ApeI-like
AbrB-like
Motif
Other DBs
NCBI-GeneID:
79244
NCBI-ProteinID:
NP_077368
RGD:
621806
Ensembl:
ENSRNOG00000015840
UniProt:
P97852
Q6IN39
Structure
PDB
PDBj
LinkDB
All DBs
Position
18:45515427..45604467
Genome browser
AA seq
735 aa
AA seq
DB search
MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSSAADKVVE
EIRRRGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIQ
RVHLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYGNFGQANYSAAKLGLLGLANTLVI
EGRKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWVKICDFSNASKPKSIQESTGGIIEVLH
KIDSEGISQNHTGQVASADASGFAGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKDL
KFVYEGSADFSCLPTFGVIVAQKSLMSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRSG
ELKCEAVIADILDKGSGIVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKAA
VAVPSRPPDAVLRDTTSLNQAALYRLSGDSNPLHIDPSFASIAGFEKPILHGLCTFGFSA
RHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNA
YVDLVPTSGVSAQTPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNVA
AKWTIDLKNGSGEVYQGPAKGSADTTITISDEDFMEVVLGKLNPQNAFFSGRLKARGNIM
LSQKLQMILKDYAKL
NT seq
2208 nt
NT seq
+upstream
nt +downstream
nt
atggcttcgcctctgaggttcgacgggcgtgtggtcctggtcaccggcgccgggggaggg
ttgggcagagcttatgccctggcttttgcagaaagaggagcattagttgttgtgaatgac
ttaggaggggacttcaaaggcgttgggaaaggctcttctgccgcagacaaggtcgtggaa
gaaataagaaggagaggcgggaaagcggtggccaattacgattcagtcgaagcaggcgag
aagcttgtgaagacagcactggacacattcggcagaatagatgttgtggtgaacaatgct
gggatcctgagggaccgttccttctctaggataagtgatgaagactgggatataattcaa
agagttcatttgcggggctccttccaagtgacccgggcagcatgggatcatatgaagaag
cagaattatggaagaatcattatgacggcctcagcttctggaatatacggcaactttggc
caggcaaattatagtgctgcaaagctgggccttctgggtctcgccaatactctcgtgatt
gaaggcaggaagaacaacattcattgtaacaccattgccccaaacgctgggtcacggatg
acagagacggtgatgccagaagacctcgttgaagccctgaagccagagtatgtggcaccg
ctggtcctttggctttgccatgagagctgtgaggaaaatggtggcttgtttgaggttgga
gcaggatggattggaaaattgcgctgggagaggaccctgggagccattgtcaggaagcgg
aatcagcccatgactcccgaggcagtgagggacaactgggtgaagatctgtgacttcagc
aatgccagcaagccgaagagcattcaagagtccacaggtggtataatcgaagttttacat
aaaatagattcagaaggaatctcacaaaatcacaccggtcaagtggcatctgcagatgca
tcaggatttgctggcgtcgttggccacaaacttccttcattttcttcttcatatacggaa
ctgcagtgcattatgtatgccctcggagtaggagcttcagtcaaaaatccaaaggacttg
aagtttgtttatgaagggagtgctgacttctcctgtttgcctacatttggagtcattgtc
gctcagaagtccttgatgagtggaggcttagcagaggttcctgggctgtcaatcaacttt
gcaaaggttcttcatggggagcagtacttggagttgtataagccacttccccgatcaggg
gaattaaaatgtgaagcagttattgctgacatcctggataaaggctctggcatagtgatt
gttatggacgtctattcttattctggcaaggaacttatatgctataatcagttctctgtc
ttcgttgttggctctggaggctttggtggaaaacggacatcagaaaaactcaaagcagct
gtagccgtaccaagtcggcctccagatgctgtactgagagataccacttcactgaatcag
gccgctctgtaccgcctcagtggagactcgaatcctttacacattgacccgagctttgcg
agcattgccggttttgagaaacccatattacacggattatgtacttttgggttttctgca
aggcatgttttacagcagtttgcggataatgatgtgtcaagattcaaggccattaaggtt
cgttttgccaaaccagtgtatccaggacaaactctacaaactgagatgtggaaggaagga
aacagaattcattttcaaaccaaggtccaagagactggagacattgtcatttccaatgca
tatgtggatcttgttcctacatctggagtttccgctcagacaccttctgagggtggagca
ctgcagagtgctcttgtatttggggaaataggtcgacgcctcaaggatgttggacgtgag
gtggtaaagaaagtaaatgctgtatttgaatggcatatcacgaaaaatgggaatgttgca
gccaagtggaccattgacctgaagaacggctctggagaggtttaccaaggccctgccaaa
ggctctgctgacacgaccatcacaatttctgatgaggatttcatggaagtggtcctgggc
aagcttaacccacagaatgccttcttcagtggcagactgaaggcccgaggaaacatcatg
ctgagccagaagctacagatgattctgaaagactatgccaagctctga
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