Rattus norvegicus (rat): 81745
Help
Entry
81745 CDS
T01003
Symbol
Pdpk1
Name
(RefSeq) 3-phosphoinositide-dependent protein kinase 1
KO
K06276
3-phosphoinositide dependent protein kinase-1 [EC:
2.7.11.1
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno01524
Platinum drug resistance
rno03320
PPAR signaling pathway
rno04068
FoxO signaling pathway
rno04071
Sphingolipid signaling pathway
rno04140
Autophagy - animal
rno04150
mTOR signaling pathway
rno04151
PI3K-Akt signaling pathway
rno04152
AMPK signaling pathway
rno04210
Apoptosis
rno04360
Axon guidance
rno04510
Focal adhesion
rno04660
T cell receptor signaling pathway
rno04664
Fc epsilon RI signaling pathway
rno04722
Neurotrophin signaling pathway
rno04910
Insulin signaling pathway
rno04919
Thyroid hormone signaling pathway
rno04931
Insulin resistance
rno04960
Aldosterone-regulated sodium reabsorption
rno05145
Toxoplasmosis
rno05205
Proteoglycans in cancer
rno05208
Chemical carcinogenesis - reactive oxygen species
rno05213
Endometrial cancer
rno05215
Prostate cancer
rno05223
Non-small cell lung cancer
rno05231
Choline metabolism in cancer
rno05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
81745 (Pdpk1)
04071 Sphingolipid signaling pathway
81745 (Pdpk1)
04151 PI3K-Akt signaling pathway
81745 (Pdpk1)
04152 AMPK signaling pathway
81745 (Pdpk1)
04150 mTOR signaling pathway
81745 (Pdpk1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
81745 (Pdpk1)
09143 Cell growth and death
04210 Apoptosis
81745 (Pdpk1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
81745 (Pdpk1)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
81745 (Pdpk1)
04664 Fc epsilon RI signaling pathway
81745 (Pdpk1)
09152 Endocrine system
04910 Insulin signaling pathway
81745 (Pdpk1)
03320 PPAR signaling pathway
81745 (Pdpk1)
04919 Thyroid hormone signaling pathway
81745 (Pdpk1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
81745 (Pdpk1)
09156 Nervous system
04722 Neurotrophin signaling pathway
81745 (Pdpk1)
09158 Development and regeneration
04360 Axon guidance
81745 (Pdpk1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
81745 (Pdpk1)
05208 Chemical carcinogenesis - reactive oxygen species
81745 (Pdpk1)
05231 Choline metabolism in cancer
81745 (Pdpk1)
09162 Cancer: specific types
05215 Prostate cancer
81745 (Pdpk1)
05213 Endometrial cancer
81745 (Pdpk1)
05223 Non-small cell lung cancer
81745 (Pdpk1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
81745 (Pdpk1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
81745 (Pdpk1)
09167 Endocrine and metabolic disease
04931 Insulin resistance
81745 (Pdpk1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
81745 (Pdpk1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rno01001
]
81745 (Pdpk1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
rno04131
]
81745 (Pdpk1)
Enzymes [BR:
rno01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
81745 (Pdpk1)
Protein kinases [BR:
rno01001
]
Serine/threonine kinases: AGC group
PDK1 family
81745 (Pdpk1)
Membrane trafficking [BR:
rno04131
]
Exocytosis
Calcium ion-dependent exocytosis
Acrosomal exocytosis proteins
81745 (Pdpk1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PH_3
PK_Tyr_Ser-Thr
Kinase-like
Pkinase_fungal
APH
ABC1
Haspin_kinase
Kdo
Motif
Other DBs
NCBI-GeneID:
81745
NCBI-ProteinID:
NP_112343
RGD:
620307
Ensembl:
ENSRNOG00000006136
UniProt:
O55173
LinkDB
All DBs
Position
10:complement(13105435..13182664)
Genome browser
AA seq
559 aa
AA seq
DB search
MARTTSQLYDAVPIQSSVVLCSCPSPSMVRSQTEPSSSPGIPSGVSRQGSTMDGTTAEAR
PSTNPLQQHPAQLPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRH
IIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSF
DETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPDSKQA
RANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKL
EYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESITWENLHQQTPPK
LTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSAVDASLPQRSGSNIEQYIH
DLDTNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLL
LTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCR
KIQEVWRQQYQSSPDAAVQ
NT seq
1680 nt
NT seq
+upstream
nt +downstream
nt
atggccaggaccaccagccagctgtatgacgctgtgcccattcagtccagtgtggtgcta
tgttcctgcccatccccatcaatggtgaggtcccagactgagcccagctcgtcccctggc
attcctagtggtgttagcaggcagggatccaccatggacggcaccacagctgaagcccga
ccaagcaccaaccccttgcagcagcaccctgcccagctgccaccacagcctcgcaagaaa
cgccctgaagacttcaagtttgggaaaattcttggcgagggctctttttcgacagttgtt
ctggcccgagaactggccacttccagagaatatgctattaaaattctggagaaacgtcat
ataataaaagaaaacaaagtcccgtatgtaactagagagagagatgtgatgtcacgcctg
gatcaccccttctttgtgaaactttactttacgtttcaggacgacgaaaagctgtatttt
ggccttagttatgccaaaaatggagagctactcaaatacatccgcaaaatcggttcattt
gatgagacctgtacccggttttacacagctgagattgtgtctgctttagagtacttgcat
ggcaagggcatcattcacagagaccttaaaccagaaaacatcttgttaaacgaagacatg
cacatccagatcacagattttggaacagccaaagtattatccccagacagcaaacaagct
agagccaattcatttgtaggaacagcgcagtatgtttctccagagctgctcacagagaag
tcggcgtgtaaaagttcagacctttgggcccttggatgtataatctatcagcttgtggca
ggacttccaccattcagagccggaaatgaatatcttatatttcagaagatcattaagttg
gaatatgatttcccagaaaaattcttccctaaggcaagagatcttgtggaaaaactcttg
gttttagatgccacaaagcgtttaggctgtgaagagatggaagggtacgggcctctcaaa
gctcatccattctttgagtccatcacgtgggagaatctgcaccagcagacgcctccgaag
ctcacagcttacttgccagccatgtcagaagatgatgaagactgctatggcaattacgac
aatctcctgagccagtttggctgcatgcaggtgtcatcctcctcctcttcccactccctg
tctgcggtggatgccagcctgccccagaggtcgggcagcaacatagagcagtacattcat
gatttggacactaactcttttgaactagacttacagttttcagaagatgaaaaaaggttg
ttattggaaaagcaagccggtggaaacccttggcaccagtttgtagaaaataatctaata
ttaaaaatgggcccagtggataagcgaaagggtttatttgcaagacgacggcagttatta
ctcacagaagggccacatttatattatgtcgatcctgtcaacaaggtcttaaaaggtgaa
attccatggtcacaagaactccgaccagaggccaagaattttaaaactttcttcgtccac
acgcctaacaggacgtattacctgatggatccaagcgggaatgctcacaagtggtgcaga
aagatccaggaggtttggaggcaacagtaccagagcagtccagatgctgctgtgcagtga
DBGET
integrated database retrieval system
