Rattus norvegicus (rat): 81751 Help Entry 81751             CDS       T01003                                  Symbol Psen2 Name (RefSeq) presenilin-2   KO K04522   presenilin 2 [EC:3.4.23.-] Organism rno  Rattus norvegicus (rat) Pathway rno04330   Notch signaling pathway rno04722   Neurotrophin signaling pathway rno05010   Alzheimer disease rno05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:rno00001]  09130 Environmental Information Processing   09132 Signal transduction    04330 Notch signaling pathway     81751 (Psen2)  09150 Organismal Systems   09156 Nervous system    04722 Neurotrophin signaling pathway     81751 (Psen2)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     81751 (Psen2)    05022 Pathways of neurodegeneration - multiple diseases     81751 (Psen2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:rno01002]     81751 (Psen2) Peptidases and inhibitors [BR:rno01002]  Aspartic peptidases   Family A22: presenilin family    81751 (Psen2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Presenilin DUF6541 Motif Other DBs NCBI-GeneID:  81751 NCBI-ProteinID:  NP_112349 RGD:  621060 Ensembl:  ENSRNOG00000002879 UniProt:  O88777 A6JGG7 LinkDB All DBs Position 13:complement(94499451..94528419) Genome browser AA seq 448 aa AA seqDB search MLTFMASDSEEEVCDERTSLMSAESPTSRSCQDSRPGPEDGENTAQWRSQENEDDCEEDP DHYACSGVPGRPSGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLI YTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLL FLFTYIYLGEVFKTYNVAMDYPTLFLAVWNFGAVGMVCIHWKGPLVLQQAYLIVISALMA LVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVW TVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEAFEAPQPGYPGEEPEEEEERGV KLGLGDFIFYSVLVGKAAATGNGDWSTTLACFIAILIGLCLTLLLLAVFKKALPALPISI TFGLIFYFSTDNLVRPFMDTLASHQLYI NT seq 1347 nt NT seq  +upstreamnt  +downstreamnt atgctcacattcatggcctctgatagcgaggaagaggtgtgcgatgagcggacgtccttg atgtcagccgagagccctacatcacgttcctgccaggacagcaggccaggcccagaggat ggagagaacactgcccagtggaggagccaggagaacgaggacgactgtgaggaggacccg gaccactatgcctgcagtggggttcctgggcgaccatcgggcctggaggaggagctgacc ctcaagtatggggcgaagcacgtgatcatgctgttcgtgcctgtcacgctgtgcatgatt gtggtggtggccaccatcaagtccgtgcgtttctacacggagaagaacgggcagctcatc tacacgcccttcaccgaggacacaccctctgtgggccagcggctcctcaactccgtgctg aacactctgatcatgatcagcgtcattgtggtcatgactatcttcctagtggtactctac aaatatcgctgttacaagttcatccatggctggctgatcatgtcctccctgatgctcctc ttcttgttcacctacatctacctcggggaagtgttcaagacctacaatgtggccatggac taccccacactgttcctggctgtctggaacttcggggcagtgggcatggtgtgcatccac tggaagggtcccctggtgctccagcaggcttacctcattgtgatcagcgcactcatggcc ctggtgttcatcaagtacctgccggagtggtccgcttgggtcatcttgggcgccatctct gtgtacgatctcgtggctgtgctgtgccccaaagggccactgaggatgctggtggaaact gcccaggaaagaaacgagcccatatttcctgccctcatatactcatctgccatggtgtgg acggtaggcatggcgaagctggacccctcctctcagggagcactgcagctcccttacgat ccagagatggaagaagactcctatgacagttttggggaaccctcataccctgaagccttc gaagctccccagcctggctacccaggggaagagccggaggaggaggaggaaaggggtgta aagcttggtctgggagacttcatcttctacagcgttctggtgggcaaggcagcagccaca ggcaacggagactggagcacgacgctggcctgctttatcgccatcctcattggcttgtgt ctcaccctcctgctgctcgccgtgttcaagaaggccctgcccgccctccccatctccatc accttcgggctcatcttttacttctccacagacaacctggtgcgtcctttcatggacacg ttggcctcccaccagctctacatctga

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