Rattus norvegicus (rat): 84021 Help Entry 84021             CDS       T01003                                  Symbol Irs3 Name (RefSeq) insulin receptor substrate 3   KO K17445   insulin receptor substrate 3 Organism rno  Rattus norvegicus (rat) Pathway rno04022   cGMP-PKG signaling pathway rno04068   FoxO signaling pathway rno04081   Hormone signaling rno04140   Autophagy - animal rno04152   AMPK signaling pathway rno04211   Longevity regulating pathway rno04213   Longevity regulating pathway - multiple species rno04910   Insulin signaling pathway rno04920   Adipocytokine signaling pathway rno04923   Regulation of lipolysis in adipocytes rno04930   Type II diabetes mellitus rno04935   Growth hormone synthesis, secretion and action rno05010   Alzheimer disease Brite KEGG Orthology (KO) [BR:rno00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     84021 (Irs3)    04022 cGMP-PKG signaling pathway     84021 (Irs3)    04152 AMPK signaling pathway     84021 (Irs3)   09133 Signaling molecules and interaction    04081 Hormone signaling     84021 (Irs3)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     84021 (Irs3)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     84021 (Irs3)    04923 Regulation of lipolysis in adipocytes     84021 (Irs3)    04920 Adipocytokine signaling pathway     84021 (Irs3)    04935 Growth hormone synthesis, secretion and action     84021 (Irs3)   09149 Aging    04211 Longevity regulating pathway     84021 (Irs3)    04213 Longevity regulating pathway - multiple species     84021 (Irs3)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     84021 (Irs3)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     84021 (Irs3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH Motif Other DBs NCBI-GeneID:  84021 NCBI-ProteinID:  NP_114463 RGD:  69317 Ensembl:  ENSRNOG00000001389 UniProt:  O08724 LinkDB All DBs Position 12:24689930..24692068 Genome browser AA seq 494 aa AA seqDB search MKPAGTGPTVSSGGESTDVSLGPPFPWPCPPDVRLCGHLRKQKSQRRRFFVLRADPPRLE CYESEKKFLASGCRPPRPRRTVSLEGACTISKRADARQRHLIVIYTSDSSLGVAAASEAE QQTWYSALLEVRATAAAAAATAMGFSPQEAPESWIFAPFQDVWPVTLRSKGLGRAPGLSS GSYRLCLGSGALSLLRKPGSKGSRDSRATPPPVLRLSLLSVRRCGHADSFFFLELGRSAP IGPGELWLQAPDAVVAQSIHETVLAAMKRLGSSAASGKAEAPLGDSPKGASAVPAPAPYE IPALALAAQARSPGERAKQDYVNPLERMGSAPSYRGPDLGGDYIAMGMRNDYVHMGGKAA EYMWMAPPGLPPPTPPRVDPRKEPEDCESTEYMPMNRFLPGPLYYEFKAREPEHGHSSAQ CSIRDRWRPMVAQPRSSQGSELSGDYMYIPDYPSARLGSLDSCLNYVDLDLVPPLEVPGA APGNSPHSYASIKF NT seq 1485 nt NT seq  +upstreamnt  +downstreamnt atgaagcctgcaggtacgggccccacagtctcctctgggggcgagtccaccgacgtgtcc ctcggcccgccgtttccttggccctgcccgcccgacgtgcggctctgtggccatctgagg aagcagaagtcccagcgccgccgctttttcgtgctgcgtgctgacccaccacggctggag tgctatgagagcgagaagaagttcttggccagcggctgccgcccacctcgaccccggcgt accgttagcctggaaggtgcctgcactattagcaagcgcgcggatgcccgtcagcgccac ctgatcgtcatctataccagcgacagcagcctgggcgtggcggcggccagtgaagcagag cagcaaacatggtacagcgccttgctcgaggtgcgcgccaccgccgctgcagctgctgcc accgctatgggtttcagcccccaagaggcccctgagtcttggatcttcgccccgttccag gacgtctggcctgtgacactgcggtccaaggggctggggagagcaccaggcctgagcagc ggcagctatcgcctgtgcctgggttctggggccctgagcctcctgcggaagccgggaagc aaaggctccagagacagccgggcaacgccaccaccagtcctgcgcttgtccttgcttagt gtgcgccgctgcggccacgcagattcctttttcttcctggaactcgggcgctcagcgccc ataggtcctggtgagctgtggctgcaggcccctgatgcagtggtggcccaaagcattcat gagaccgtcctggctgccatgaagagactggggagcagtgcagccagtggcaaagctgag gcaccgctgggagattctccaaagggggcttctgcagtccctgccccagcaccatatgag atccctgctttggcactggcagcacaagcgagaagtccgggtgagagagcgaagcaggac tacgtcaatccactggaaaggatggggtcagcaccctcctacagggggccagatctgggt ggggactacatcgccatgggaatgaggaatgactatgtgcacatgggggggaaagctgct gagtacatgtggatggcgcccccaggtctccctccccccacccctcccagggtagatccc agaaaggagcctgaggattgtgagagcacagagtatatgcccatgaacagatttttaccg gggcctctttactacgagttcaaggccagggagcctgaacatgggcattctagtgcccag tgtagcattagggacagatggagacccatggtggctcagccccgctcttcccaagggtca gagctctctggggactacatgtacatccctgactatcccagtgctaggctggggtctctg gacagctgcctcaactatgtggacctggacctagtccctcccctggaggttcctggagcg gccccagggaatagtccacatagctatgccagcatcaagttctag

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