Rhinopithecus roxellana (golden snub-nosed monkey): 104655130
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Entry
104655130 CDS
T03989
Symbol
BACE2
Name
(RefSeq) beta-secretase 2 isoform X1
KO
K07747
beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:
3.4.23.45
]
Organism
rro
Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
rro00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
104655130 (BACE2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
rro01002
]
104655130 (BACE2)
Enzymes [BR:
rro01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.45 memapsin 1
104655130 (BACE2)
Peptidases and inhibitors [BR:
rro01002
]
Aspartic peptidases
Family A1: pepsin family
104655130 (BACE2)
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Motif
Pfam:
Asp
TAXi_C
TAXi_N
Motif
Other DBs
NCBI-GeneID:
104655130
NCBI-ProteinID:
XP_010352820
UniProt:
A0A2K6RBI3
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Position
13:43277886..43394207
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AA seq
518 aa
AA seq
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MGTLARALLLPLLAQWLLRAAPELAPAPFTLPLRVAAATNRVVAPTPGPETPAERRADGL
ALALEPALESAAGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAG
APHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNSSFLVNIATI
FESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVA
GSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKA
IVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWAHSETPWSYFPKISI
YLRDENSSRSFRITVLPQLYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFYVIFD
RARKRVGFAASPCAEIAGAAVSEISGPFSTEDIASNCVPAQSLSEPILWIVSYALMSVCG
AILLVLIVLLLLPFRCQRRPRDPEVVNDESSLVRHRWK
NT seq
1557 nt
NT seq
+upstream
nt +downstream
nt
atgggcacgctggcccgggcgctgctgctgcctctgctggcccagtggctcctgcgcgcc
gccccggagctggcccccgcgcccttcacgctgcccctccgggtggccgcggccacgaac
cgcgtggttgcgcccaccccgggacccgagacccccgccgagcgccgcgccgacggcctg
gcgctcgccctagagcctgccctggagtccgccgcgggcgccgccaacttcttggccatg
gtggacaacctgcagggggactctggccgcggctactacctggagatgctgatcgggacc
cccccgcagaagctacagattctcgttgacactggaagcagtaactttgccgtggcagga
gctccgcactcctacatagacacgtactttgacacagagaggtctagcacataccgctcc
aagggctttgacgtcactgtgaagtacacacaaggaagctggacgggcttcgtcggggaa
gacctcgtcaccatccccaaaggcttcaatagttcttttcttgtcaacattgccactatt
tttgaatcagagaatttctttttgcctgggattaaatggaatggaatacttggcctagct
tatgccacacttgccaagccatcaagttccctggagaccttctttgactccctggtgaca
caagcaaacatccccaatgttttctccatgcagatgtgtggagccgggttgcccgttgct
ggatctgggaccaacggaggtagtcttgtcctgggtggaattgaaccaagtttgtataaa
ggagacatctggtatacccctattaaggaggagtggtactaccagatagaaattctgaaa
ttggaaattggaggccaaagccttaatctggactgcagagagtataacgcggacaaggcc
atcgtggacagtggtaccacgctgctgcgcctgccccagaaggtgttcgatgcagtggtg
gaagctgtggcccgcgcatctctgattccagaattctctgatggcttctggaccgggtcc
cagctggcgtgctgggcgcattcggaaacaccttggtcttatttccctaaaatctccatc
tacctgagagacgagaactccagcaggtcgttccgcatcacagtcctgcctcagctttac
attcagcccatgatgggggccggcctgaattatgaatgttaccgattcggcatttcccct
tccacaaatgcgctggtgattggtgccacggtgatggagggcttctacgtcatcttcgac
agagcccggaagagggtgggcttcgcagcgagcccctgtgcagaaattgcaggtgctgca
gtgtctgaaatttccgggcctttctcaacagaggacatagccagcaactgtgtgcccgct
cagtctttgagcgaacccattttgtggatcgtgtcctatgcgctcatgagcgtctgtgga
gccatcctccttgtcttaatcgtcctgctgctgctgccgttccggtgtcagcgtcgcccc
cgtgaccctgaggtcgtcaatgatgagtcctctctggtcagacatcgctggaaatga
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