KEGG   Rhinopithecus roxellana (golden snub-nosed monkey): 104664316
Entry
104664316         CDS       T03989                                 
Symbol
PAK1
Name
(RefSeq) serine/threonine-protein kinase PAK 1 isoform X5
  KO
K04409  p21-activated kinase 1 [EC:2.7.11.1]
Organism
rro  Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro04010  MAPK signaling pathway
rro04012  ErbB signaling pathway
rro04014  Ras signaling pathway
rro04024  cAMP signaling pathway
rro04062  Chemokine signaling pathway
rro04360  Axon guidance
rro04392  Hippo signaling pathway - multiple species
rro04510  Focal adhesion
rro04625  C-type lectin receptor signaling pathway
rro04650  Natural killer cell mediated cytotoxicity
rro04660  T cell receptor signaling pathway
rro04666  Fc gamma R-mediated phagocytosis
rro04810  Regulation of actin cytoskeleton
rro05132  Salmonella infection
rro05170  Human immunodeficiency virus 1 infection
rro05205  Proteoglycans in cancer
rro05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:rro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    104664316 (PAK1)
   04012 ErbB signaling pathway
    104664316 (PAK1)
   04014 Ras signaling pathway
    104664316 (PAK1)
   04392 Hippo signaling pathway - multiple species
    104664316 (PAK1)
   04024 cAMP signaling pathway
    104664316 (PAK1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    104664316 (PAK1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    104664316 (PAK1)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    104664316 (PAK1)
   04650 Natural killer cell mediated cytotoxicity
    104664316 (PAK1)
   04660 T cell receptor signaling pathway
    104664316 (PAK1)
   04666 Fc gamma R-mediated phagocytosis
    104664316 (PAK1)
   04062 Chemokine signaling pathway
    104664316 (PAK1)
  09158 Development and regeneration
   04360 Axon guidance
    104664316 (PAK1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    104664316 (PAK1)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    104664316 (PAK1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    104664316 (PAK1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    104664316 (PAK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rro01001]
    104664316 (PAK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rro04131]
    104664316 (PAK1)
   03036 Chromosome and associated proteins [BR:rro03036]
    104664316 (PAK1)
Enzymes [BR:rro01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     104664316 (PAK1)
Protein kinases [BR:rro01001]
 Serine/threonine kinases: STE group
  STE20 family
   104664316 (PAK1)
Membrane trafficking [BR:rro04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    104664316 (PAK1)
 Endocytosis
  Macropinocytosis
   Kinases
    104664316 (PAK1)
Chromosome and associated proteins [BR:rro03036]
 Eukaryotic type
  Sister chromatid separation proteins
   Aurora kinases
    Regulators of Aurora kinases
     104664316 (PAK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PBD ABC1 Kinase-like Pkinase_fungal APH DSHCT
Other DBs
NCBI-GeneID: 104664316
NCBI-ProteinID: XP_010364087
UniProt: A0A2K6RTM5
LinkDB
Position
15:54691880..54842068
AA seq 545 aa
MSNNGLDIQDKPPAPPMRNTSTMIGAGSKDTGTLNHGSKPLPPNPEEKKKKDRFYRSILP
GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKN
PQAVLDVLEFYNSKKTSNSQKYMSFTDKSAEDYNSSNALNVKAVSETPAVPPVSEDEDDD
DDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTSTRDVATSPISPTENNTTPPDALTRNTE
KQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQ
MNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETC
MDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSK
RSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNG
TPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEA
TKNNH
NT seq 1638 nt   +upstreamnt  +downstreamnt
atgtcaaataacggcctagacattcaagacaaacccccggcccctccgatgagaaatacc
agcactatgattggagctggcagcaaagatactggaaccctaaaccatggttctaaacct
ctgcctccaaacccagaggagaagaaaaagaaggaccgattttaccgatccatcttacct
ggagataaaacaaataaaaagaaagagaaagagcggccagagatttctctcccttcagat
tttgaacacacaattcatgttggttttgatgctgtcacaggggagtttacgggaatgcca
gagcagtgggcccgcttgcttcagacatcaaatatcactaagtcggagcagaagaaaaac
ccgcaggctgttctggatgtgttggagttttacaactcaaagaagacatccaacagccag
aaatacatgagctttacagataagtcagctgaggattataattcttctaatgccttgaat
gtgaaggctgtgtctgagactcctgcagtgccaccagtttcagaagatgaggatgatgat
gatgatgatgctaccccaccgccagtgattgctccacgcccagagcacacaaaatctgta
tacacacggtctgtgattgaaccacttcctgtcacttcaactcgggacgtggctacatct
cccatttcacctactgaaaataacaccactccaccagatgctttgacccggaatactgag
aagcagaagaagaagcctaaaatgtctgatgaggagatcttggagaaattacgaagcata
gtgagtgtgggcgatcctaagaagaaatatacacggtttgagaagattggacaaggtgcg
tcaggcaccgtgtacactgcaatggatgtggccacaggacaggaggtggccattaagcag
atgaatcttcagcagcagcccaagaaagagctgattattaatgagatcctggtcatgagg
gaaaacaagaacccaaacattgtgaattacttggacagttacctcgtgggagatgagcta
tgggttgttatggaatacttggctggaggctccttgacagacgtagtgacagaaacatgc
atggatgaaggccagattgcagctgtgtgccgtgagtgtctgcaggctctggagtttttg
cattcgaaccaggtcattcacagagacatcaagagtgacaatattctgttgggaatggat
ggctctgtcaagctaactgattttggattctgtgcacagataaccccagagcagagcaaa
cggagcaccatggtgggaaccccatactggatggcaccagaggttgtgacacgaaaggcc
tatgggcccaaggttgacatctggtccctgggcatcatggccatcgaaatgattgaaggg
gagcctccatacctcaatgaaaaccctctgagagccttgtacctcattgccaccaatggg
accccagaacttcagaacccagagaagctgtcagctatcttccgggactttctgaaccgc
tgtcttgagatggatgtggagaagagaggttcagctaaagagctgctgcagcatcagttc
ctgaagattgccaagcccctctctagcctcactccactgattgctgcagcaaaggaggca
acaaagaacaatcactaa

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