Rhinopithecus roxellana (golden snub-nosed monkey): 104675158
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Entry
104675158 CDS
T03989
Symbol
PTEN
Name
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1
KO
K01110
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:
3.1.3.16
3.1.3.48
3.1.3.67
]
Organism
rro
Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro00562
Inositol phosphate metabolism
rro01100
Metabolic pathways
rro01521
EGFR tyrosine kinase inhibitor resistance
rro04068
FoxO signaling pathway
rro04070
Phosphatidylinositol signaling system
rro04071
Sphingolipid signaling pathway
rro04115
p53 signaling pathway
rro04140
Autophagy - animal
rro04150
mTOR signaling pathway
rro04151
PI3K-Akt signaling pathway
rro04218
Cellular senescence
rro04510
Focal adhesion
rro04931
Insulin resistance
rro05165
Human papillomavirus infection
rro05166
Human T-cell leukemia virus 1 infection
rro05200
Pathways in cancer
rro05206
MicroRNAs in cancer
rro05208
Chemical carcinogenesis - reactive oxygen species
rro05213
Endometrial cancer
rro05214
Glioma
rro05215
Prostate cancer
rro05218
Melanoma
rro05222
Small cell lung cancer
rro05224
Breast cancer
rro05225
Hepatocellular carcinoma
rro05230
Central carbon metabolism in cancer
rro05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
rro05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
rro00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
104675158 (PTEN)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
104675158 (PTEN)
04070 Phosphatidylinositol signaling system
104675158 (PTEN)
04071 Sphingolipid signaling pathway
104675158 (PTEN)
04151 PI3K-Akt signaling pathway
104675158 (PTEN)
04150 mTOR signaling pathway
104675158 (PTEN)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
104675158 (PTEN)
09143 Cell growth and death
04115 p53 signaling pathway
104675158 (PTEN)
04218 Cellular senescence
104675158 (PTEN)
09144 Cellular community - eukaryotes
04510 Focal adhesion
104675158 (PTEN)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
104675158 (PTEN)
05206 MicroRNAs in cancer
104675158 (PTEN)
05208 Chemical carcinogenesis - reactive oxygen species
104675158 (PTEN)
05230 Central carbon metabolism in cancer
104675158 (PTEN)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
104675158 (PTEN)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
104675158 (PTEN)
05214 Glioma
104675158 (PTEN)
05218 Melanoma
104675158 (PTEN)
05215 Prostate cancer
104675158 (PTEN)
05213 Endometrial cancer
104675158 (PTEN)
05224 Breast cancer
104675158 (PTEN)
05222 Small cell lung cancer
104675158 (PTEN)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
104675158 (PTEN)
05165 Human papillomavirus infection
104675158 (PTEN)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
104675158 (PTEN)
09167 Endocrine and metabolic disease
04931 Insulin resistance
104675158 (PTEN)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
104675158 (PTEN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
rro01009
]
104675158 (PTEN)
Enzymes [BR:
rro01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.16 protein-serine/threonine phosphatase
104675158 (PTEN)
3.1.3.48 protein-tyrosine-phosphatase
104675158 (PTEN)
3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
104675158 (PTEN)
Protein phosphatases and associated proteins [BR:
rro01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Dual specificity phosphatases)
Phosphatase and Tensin homologs (PTEN)
104675158 (PTEN)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PTEN_C2
Tc-R-P
PTP-SAK
DSPc
PTP-NADK
Y_phosphatase
PTPlike_phytase
Y_phosphatase3
DUF3256
Motif
Other DBs
NCBI-GeneID:
104675158
NCBI-ProteinID:
XP_010377926
UniProt:
A0A2K6PC42
LinkDB
All DBs
Position
11:62468472..62573257
Genome browser
AA seq
403 aa
AA seq
DB search
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK
HKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA
AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSY
LLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMY
FEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEI
DSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEAS
SSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
NT seq
1212 nt
NT seq
+upstream
nt +downstream
nt
atgacagccatcatcaaagagatcgttagcagaaacaaaaggagatatcaagaggatgga
ttcgacttagacttgacctatatttatccaaacattattgctatgggatttcctgcagaa
agacttgaaggcgtatacaggaacaatattgatgatgtagtaaggtttttggattcaaag
cataaaaaccattacaagatatacaatctttgtgctgaaagacattatgacaccgccaaa
tttaattgcagagttgcacaatatccttttgaagaccataacccaccacagctagaactg
atcaaacccttttgtgaagatcttgaccaatggctaagtgaagatgacaatcatgttgca
gcaattcactgtaaagctggaaagggacgaactggtgtaatgatttgtgcatatttatta
catcggggcaaatttttaaaggcacaagaggccctagatttctatggggaagtaaggacc
agagacaaaaagggagtaactattcccagtcagaggcgctatgtgtattattatagctac
ctgttaaagaatcacctggattatagaccagtggcactgttgtttcacaagatgatgttt
gaaactattccaatgttcagtggcggaacttgcaatcctcagtttgtggtctgccagcta
aaggtgaagatatattcctccaattcaggccccacacgacgggaagacaagttcatgtac
tttgagttccctcagccattacctgtgtgtggtgatatcaaagtagaattcttccacaaa
cagaacaagatgctaaaaaaggacaaaatgtttcacttttgggtaaatacattcttcata
ccaggaccagaggaaacctcagaaaaagtagaaaatggaagtctatgtgatcaagaaatt
gatagcatttgcagtatagagcgtgcagataatgacaaggaatatctagtacttacttta
acaaaaaatgatcttgacaaagcaaataaagacaaagccaaccgatacttttctccaaat
tttaaggtgaagctgtacttcacaaaaacagtagaggagccgtcaaatccagaggctagc
agttcaacttctgtaacaccagatgttagtgacaatgaacctgatcattatagatactct
gacaccactgactctgatccagagaatgaaccttttgatgaagatcagcatacacaaatt
acaaaagtctga
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