Rhinopithecus roxellana (golden snub-nosed monkey): 104677021
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Entry
104677021 CDS
T03989
Symbol
PSEN2
Name
(RefSeq) presenilin-2 isoform X1
KO
K04522
presenilin 2 [EC:3.4.23.-]
Organism
rro
Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro04330
Notch signaling pathway
rro04722
Neurotrophin signaling pathway
rro05010
Alzheimer disease
rro05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
rro00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
104677021 (PSEN2)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
104677021 (PSEN2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
104677021 (PSEN2)
05022 Pathways of neurodegeneration - multiple diseases
104677021 (PSEN2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
rro01002
]
104677021 (PSEN2)
Peptidases and inhibitors [BR:
rro01002
]
Aspartic peptidases
Family A22: presenilin family
104677021 (PSEN2)
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GFIT
Motif
Pfam:
Presenilin
DUF6541
Motif
Other DBs
NCBI-GeneID:
104677021
NCBI-ProteinID:
XP_010380221
UniProt:
A0A2K6PAS8
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Position
8:90220914..90248189
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AA seq
448 aa
AA seq
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MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDP
DRYVYSGVSGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLI
YTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLL
FLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMA
LVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVW
TVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLTGYPAEELEEEEERGV
KLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISI
TFGLIFYFSTDNLVRPFMDTLASHQLYI
NT seq
1347 nt
NT seq
+upstream
nt +downstream
nt
atgctcacattcatggcctctgacagcgaggaagaagtatgtgatgagcggacatcccta
atgtcggccgagagccccacaccacgctcctgccaggagggcaggcagggcccagaggac
ggagagaacactgcccagtggagaagccaggagaacgaggaggacggtgaggaggaccct
gaccgctacgtctatagtggggtttccgggcggccgccaggcctggaggaagagctgacc
ctcaagtacggggcgaagcacgtgatcatgctgtttgtgccggtcactctgtgcatgatc
gtggtggtagccaccatcaagtctgtgcgcttctacacggagaagaatggacagctcatc
tacacgccattcactgaggacacgccctcggtgggccagcgcctcctcaactctgttctc
aacaccctcatcatgatcagcgtcatcgtggttatgaccatcttcttggtggtgctctac
aagtaccgctgctacaagttcatccatggctggttgatcatgtcttcgctgatgctgctg
ttcctcttcacctatatctaccttggggaagtgctcaagacctacaatgtggccatggac
taccccaccctcttgctgactgtctggaacttcggggcggtgggcatggtgtgtatccac
tggaagggccccctggtgctgcagcaggcctacctcatcatgatcagtgcactcatggcc
ttggtgttcatcaagtacctcccagagtggtctgcgtgggtcatcctgggcgccatctct
gtgtacgatctcgtggctgtgctgtgtcccaaagggcctctgagaatgctggtagaaact
gcccaggagagaaacgagcccatattccctgccctgatatactcatccgccatggtgtgg
acggtcggcatggcgaagctggacccctcctctcagggtgccctccagctcccctatgac
ccggagatggaagaagactcctatgacagttttggggagccttcataccccgaagtcttt
gagcctcccctgactggctacccagcggaggaactggaggaagaggaggaaaggggtgtg
aagcttggcctcggggacttcatcttctacagtgtgctggtgggcaaggcggcggccacg
ggcagcggggactggaataccacgctggcctgcttcgtcgccatcctcattggcttgtgt
ctgacccttctgctgcttgctgtcttcaagaaggcgttgcccgccctccccatctccatc
acgtttgggctcatcttttacttctccacggacaacctggtgcgaccattcatggacacc
ctggcctcccatcagctctacatctga
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