KEGG   Roseiflexus sp. RS-1: RoseRS_0064
Entry
RoseRS_0064       CDS       T00542                                 
Name
(GenBank) methionine synthase (B12-dependent)
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
rrs  Roseiflexus sp. RS-1
Pathway
rrs00270  Cysteine and methionine metabolism
rrs00450  Selenocompound metabolism
rrs00670  One carbon pool by folate
rrs01100  Metabolic pathways
rrs01110  Biosynthesis of secondary metabolites
rrs01230  Biosynthesis of amino acids
rrs04980  Cobalamin transport and metabolism
rrs04981  Folate transport and metabolism
Module
rrs_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:rrs00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    RoseRS_0064
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    RoseRS_0064
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    RoseRS_0064
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    RoseRS_0064
   04980 Cobalamin transport and metabolism
    RoseRS_0064
Enzymes [BR:rrs01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     RoseRS_0064
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding B12-binding_2
Other DBs
NCBI-ProteinID: ABQ88507
UniProt: A5UPF4
LinkDB
Position
78141..81905
AA seq 1254 aa
MRLPEPHAGAWGFLLHKRESAIIAPASPIITCRQFGYEVSRGVSLKKPTYLEALRERVLI
YDGAMGTSIDTFHLTAADYGGENTFGARDYLVMTRPDVIEQIHTSFLEAGADVLETCTFQ
STRIRLEEWGLADQTHAINVAAARLARRVADAFEARDGRPRYVAGSMGPTGKLPSSDDPS
LSDITFDQLSDIFYEQAVALIEGGVDVLLVETSVDILEVKAALDGIRRAKADLNRPDVAV
QAQVFLDLSGKMLLGTEVPALVATLEAMPVDVIGLNCSTGPEHMREAIRYMTRHSRKPIS
CIPNAGLPIEVNGETVYPMEPEPFARILGEYVHEYGVAVVGGCCGTRPAHIRRLRQVVGA
ATPPKVRDIEYIPSVSSGVRAAALRQEGTLTIIGERVNTLGSRKVKRLLLNDDYDGVLEV
AREQVDSGSHILDVCVAMTERSDEREMMVRLLKKLTMNIELPLAIDTTEADVLNAALAIY
PGRAIVNSVSLEGGRGDKIDRTMPLVARYGAATIAMTIDEEGMAHTAERKLAIARRIAQI
AQDEYGVPPEALIFDVLTFPITTGQPELRRAAIETIEGIRLVKQHIPGCFTTLGVSNLSF
GVAPYARAALNSVFLKHAVDAGLDTAIINPAHVMPYAEIPPEQIRVCEDLIFDRDEQALA
RFIQFFEEHGSAAKTERVDPTEGMTAAQRVHWKIVHRKKEGIEQDIDTVIAERIREAEMR
AGIHDSALDPAHPSREAIFASPFRNSAAVDVLNTVLLPAMKEVGDLFGAGQLILPFVLQS
AEVMKKAVAHLEQYLEKLEGVTKGKIVLATVYGDVHDIGKNLVHTILANNGYTVYDLGKQ
VPINTIIEKAVEVNADAIGLSALLVSTSKQMPLCVQELHRRGLKFPVLVGGAAINKQYGQ
RILFVDDHTPYEPGVFYCKDAFEGLETVDALVDPSTRATFIERTKAEAAEALGKKQRGRV
ALAELGRATLSDTAKVRSAVRTDVPVPTPPFWGARVLTRIKLADVVECLDRNALYRLQWG
AKNAKGEEWEHLKADFDAKVRDLIREAERDGWLEPKVVYGYYPCQSDGHEVIVYDPPSVL
NGAQPRELTRFVFPRQPERERLCLADYFRSRESGEYDVVGLQIVTMGRKVDDLTETLQQS
GDYSRAYFIHGLGVSLAEALAEYTNRLIRRQLGLKGTQGKRYSWGYPACPDLEEHEKLFR
VLPAAEIGVTLTEAWQLVPEQSTAAIVIHHPEAKYFSIGSARERAEEDVAETLA
NT seq 3765 nt   +upstreamnt  +downstreamnt
atgaggcttccggaacctcacgcgggcgcgtggggttttttgctgcacaagcgagaaagc
gcaatcatcgcacccgccagcccgatcatcacgtgcagacagttcggatatgaagtatca
cgaggtgtttccttgaagaagccaacctaccttgaagccctgcgcgagcgcgtcctgatc
tacgacggcgctatgggcaccagcatcgatacattccatctcacggctgcggactatggc
ggtgaaaacactttcggcgcccgcgattatctggtgatgactcgcccggatgtcatcgaa
cagatccacacctcgtttctggaagcaggcgcagatgtgctcgaaacatgcacgttccaa
tcgacccgcatccggcttgaggaatgggggcttgccgatcagacgcatgcgatcaatgtc
gccgctgcgcgcctggcgcggcgcgttgctgatgcgttcgaggcgcgtgatggtcgtccg
cgttacgtcgccggctcgatgggaccgaccggcaagttgccctcttccgatgatccgtcg
ctctctgatataacgttcgatcaactctccgatatcttctacgaacaggcggtggcgctg
atcgaaggcggggtcgatgtgctgctggtcgagacgagcgttgacattcttgaagtgaaa
gcagcactcgacggcattcgtcgcgcgaaagcggatcttaaccgtcctgatgtcgccgtg
caggcgcaggtgttcctcgatctctccggcaagatgctgcttggcaccgaggtgccagcg
ctcgttgccaccctggaagcgatgccggtcgatgtcatcgggctgaactgttcaaccggt
cctgaacatatgcgcgaggcgatccggtatatgacccgccactcgcgcaagccgatctcc
tgcattcccaacgccggtctgccgatcgaggtgaatggcgagacggtctatccgatggag
ccggagccgttcgcccgcattctgggggagtatgtccacgagtatggagtggcggtcgtt
ggaggatgctgcggcacccgcccggcgcacattcgccgtttgcgccaggtagtcggcgcg
gcgacgccgccgaaagtgcgtgacatcgagtacatccccagcgtctcgtcgggggtgcgc
gcggctgcattgcgccaggaagggacgttgaccattatcggcgaacgggtcaacaccctc
ggttcgcgtaaagtcaagcgcctgctgctgaacgatgactacgacggcgtgcttgaagtc
gcgcgcgagcaggtcgattcaggatcacatattctcgatgtgtgcgtggcaatgaccgag
cgatccgacgagcgtgagatgatggtcagactgttgaagaagttgaccatgaacatcgaa
ctgccgctggcgatcgatacgaccgaagccgatgtgctcaatgcggcgctggcgatctac
cccggtcgcgcgattgtcaactcggtgtcgctcgaaggcggtcgtggcgataagattgac
cgcaccatgccgctggtggcgcgctatggtgcggcaacgatcgccatgaccatcgatgaa
gaaggtatggcgcacactgccgaacgtaaactggcaatcgcccggcgtatcgctcagatt
gcgcaggacgagtacggcgtgccgcccgaagcgctgatcttcgatgtgttgactttccct
atcacgaccggtcaacccgagttgcgccgcgcagcgatcgaaacaatcgagggtattcgc
ctggtgaagcagcatattcccggctgtttcaccaccctcggcgtcagcaacctgagtttc
ggcgtcgcaccgtacgcgcgtgcagcgctcaactcggtgtttctgaaacatgcagtcgat
gccggtctcgatacggcgatcatcaatccggcgcatgtgatgccgtatgccgagattccg
ccggagcagatcagggtctgcgaagacctgatcttcgaccgcgacgagcaggcgctggcg
cggttcattcagttcttcgaggagcacggatcggcagcaaaaaccgagcgcgtcgatccg
acggaggggatgacagcggcgcagcgcgtccactggaagatcgtgcaccgcaagaaagag
ggcatcgagcaggatatcgatacggtcatcgctgaacgcatccgcgaggcggagatgcgt
gcaggcatccacgatagcgccctcgatccggcgcatccctcgcgggaggcgatcttcgcc
tcgcccttccgcaatagtgctgcggttgatgtgctcaacactgtgctgctccctgcgatg
aaggaggtcggcgacctgttcggcgcgggtcagttgatccttcccttcgtattgcagagc
gccgaggtgatgaagaaagcggttgcgcacctggagcagtatctggaaaaactcgaaggg
gtcaccaaaggcaagatcgtcctggcgacggtgtacggcgatgttcacgacatcggcaaa
aatctggttcatacgatccttgccaacaacgggtatacggtgtacgacctggggaagcag
gtgccgatcaacaccattatcgagaaggcggtcgaagtcaacgccgacgcgattggtctg
tcggcgcttctggtgagcacctcgaagcagatgccgctctgcgtgcaggaattgcaccgg
cgtggtctcaagttcccggtgctggtcggcggtgcggcgatcaacaaacagtacgggcag
cgcattctgttcgttgatgaccacactccttacgaacctggcgtcttctactgtaaagac
gcattcgagggtctggaaacggtcgacgctctggtggatccgtccacccgcgcaacattc
atcgaacgcacgaaagcggaagcagctgaggcgctcggcaagaagcaacgcggtcgcgtg
gcgctggcggaactggggcgcgcaacattgagcgatacggcgaaggtgcgctcggcggtg
cgaaccgatgtgccggttccgacgccgccgttctggggtgcgcgcgtgttgacgcgcatc
aaactggcggatgtggtcgaatgcctggatcgcaatgcgctctaccggcttcagtgggga
gcaaagaatgcgaaaggcgaagagtgggaacacctgaaggcggattttgatgcaaaagtg
cgcgatctgatccgcgaagccgaacgcgatggctggctcgagccgaaagtggtctatggc
tactacccctgccagagtgacgggcacgaggttattgtctacgatccgccatcggtgctc
aacggcgcccagccgcgcgaactcacgcgcttcgtcttcccgcgtcaaccggagcgtgaa
cgtctctgcctggctgactatttccgttcacgcgagagcggcgagtacgatgtggttggg
ttgcagatcgtaaccatggggcgcaaagtcgacgacctgaccgagacgttgcagcaatcc
ggcgattattcgcgtgcgtacttcatccatgggctgggggtatcgctggcggaggcgctc
gccgagtatacgaaccgtctcatccgccggcaactggggctgaaaggaacccagggcaag
cgttactcctgggggtatcccgcctgccccgacctggaagagcacgagaagttgttcagg
gtgcttccagcggctgagatcggcgtgacgctcaccgaagcctggcaactggtgccggag
cagagcacggcggcgattgtgatccaccatcctgaggcgaaatacttctcgatcggctct
gcccgcgaacgcgctgaagaggatgtcgccgaaacgctggcgtaa

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