Rana temporaria (common frog): 120928726
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Entry
120928726 CDS
T07929
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1-like
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
rtem
Rana temporaria (common frog)
Pathway
rtem00140
Steroid hormone biosynthesis
rtem01100
Metabolic pathways
Module
rtem_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
rtem_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
rtem_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
rtem_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
rtem00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
120928726
Enzymes [BR:
rtem01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
120928726
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
120928726
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
NAD_binding_4
GDP_Man_Dehyd
Polysacc_synt_2
NAD_binding_10
RmlD_sub_bind
KR
Sacchrp_dh_NADP
NmrA
Ldh_1_N
Semialdhyde_dh
adh_short
Ge1_WD40
Motif
Other DBs
NCBI-GeneID:
120928726
NCBI-ProteinID:
XP_040195654
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Position
2:complement(537350570..537359671)
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AA seq
379 aa
AA seq
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MTASSLSGVSCLVTGASGFVGRRIVQMLLEEEPELEELRVMDKNLSEDLLKTCQRFQDRT
TVKTLQGDIRDTDFLHRCCQGVSLVIHAAAIIDTVGKVRKDVVMSINVTGTEQLLEACLQ
NNVPYFIFTSSIEVCGPNPQGDPIVNGTEETAYASKPGFCYGESKSLAEKKVLEANGQEL
QNGGTLTTCSLRPVYVFGEGSQFLQIHLDQALLNGDVFHRTSRKEALVNPVYVGNVAWAH
LLAARAMKDPEGTKKIAGNFYFLTDDTPHMSYSDLNHALGKELGLRVERKLAMPLPVLYI
VASLMEMVGFVLRPFVRFVPPFTRHLLTILNTPFTFTYRKLQSDAGYKPRYSWEEARQVT
SDWMASVIPQRRELLRKKK
NT seq
1140 nt
NT seq
+upstream
nt +downstream
nt
atgactgccagctcgctctcgggggtctcctgtctggtgacgggggccagcggcttcgtc
gggcgcaggattgtccagatgttgctggaggaagagccggaactggaggaactccgggtc
atggacaagaacttgagtgaggacctcctgaagacctgccagaggttccaggacaggacg
acggtgaagacgctgcaaggtgacatccgagacaccgacttcctgcaccggtgctgccag
ggggtcagcctggtcatccacgccgcggccattatcgacacggtgggcaaagtgagaaaa
gacgtcgtcatgtccatcaatgtgaccgggacggagcagctgttggaggcgtgcctacag
aacaacgtgccgtacttcatcttcaccagcagtatagaggtctgcggaccaaacccccaa
ggggaccccattgttaatggcacagaggagacggcgtatgccagtaagccgggcttctgc
tacggagagagcaagagcttggcggaaaagaaggtcttggaggccaacggtcaggagctc
cagaatgggggaactctgaccacctgttctctccgtcccgtatacgtcttcggtgaaggg
tctcagttcctccaaattcatttggaccaagctctactgaacggcgacgtcttccatagg
acctccaggaaagaggccttggtcaacccggtgtacgtcggtaacgttgcctgggcccac
ctattggcggctcgggccatgaaggacccggaaggaaccaagaagatagccgggaacttc
tacttccttaccgatgacaccccccacatgagctactcggacctgaaccacgctctgggc
aaggagctgggcctaagggtggagaggaaattggccatgcccctccccgtcctctatatc
gtggcttccttaatggagatggtcggctttgttcttcggccgtttgtaaggttcgtgccg
ccctttaccaggcacctgctgacaatcctgaacacccccttcaccttcacgtacaggaag
ctgcagagcgacgcggggtacaagccgcgatacagctgggaggaggccaggcaggtgaca
agtgattggatggcgtcggtgataccccaacgtagggagctcctcagaaagaaaaaataa
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