Streptomyces actuosus: DMT42_10995
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Entry
DMT42_10995 CDS
T08084
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sact
Streptomyces actuosus
Pathway
sact00010
Glycolysis / Gluconeogenesis
sact00020
Citrate cycle (TCA cycle)
sact00620
Pyruvate metabolism
sact00785
Lipoic acid metabolism
sact01100
Metabolic pathways
sact01110
Biosynthesis of secondary metabolites
sact01120
Microbial metabolism in diverse environments
sact01200
Carbon metabolism
sact01210
2-Oxocarboxylic acid metabolism
Module
sact_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sact00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
DMT42_10995 (aceE)
00020 Citrate cycle (TCA cycle)
DMT42_10995 (aceE)
00620 Pyruvate metabolism
DMT42_10995 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
DMT42_10995 (aceE)
Enzymes [BR:
sact01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
DMT42_10995 (aceE)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF3135
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AWT42795
UniProt:
A0A2U9P0X3
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Position
2325893..2328595
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AA seq
900 aa
AA seq
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MTDPNAIQPSELDQLPDRDPEETAEWQASLDAVAKAAGPHRAAYLMRRTLERAEGAGIAL
PKLLETDYVNTIPTAAEPELPGDPEMEARITAWNRWNAAAMVTRGAKHGVGGHIATFASA
AWLYETGFNHFFKGKEGDGSGDQLYIQGHASPGIYARAFLDGRLTEQHLDNFRQEAGGNG
LPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTNRGIKDVSASHVWAFLGDGEM
DEPESTAALALAAREQLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVVKTL
WGSAWDELFQLDTTGALVRRLREVPDAQVQTYQTRDAAYIREDFFGKDPALAEMAKLLSD
DKILEIFHVSRGGHEPRKVYAAYKAAVEHKGAPTVILAQTVKGHTLGEGFASKNANHQMK
KLSVDEFKAMRDLLGLPIKDSDFVDGVVPYGHPGADSPEVRYLQERRAALGGPAPARRTH
PLPALPAPAEKAFASFDKGSGSQNVATTMAFVRLIKDLVRDKETGKRWVPIVPDEARTFG
MESLFPSLGIYSPKGQTYEPVDRDQLMYYKEAKNGQILNEGITEAGSMADFIAASTSYAT
HGEAMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLVGATAGRTTLTGEGLQHADGHSPV
IAATNPAALTYDPAFAYEIAVIVREGLRRMYGEAKPGEDQDVFYYLTVYNEPLPQPAKPQ
GLGIDEGIVKGLYRFNTAESAGVTVPANAPRIQLLGSGTAIHWALEAQKLLAEEWGVAAD
VWSATSWTELRRDALEADEALLRGEERVPYVRQALQGAEGPVLAVSDYMRQVPDQIAQWV
EQDWSSLGADGFGLSDTREAARRHFGVDAPSIVVAALAQLARRGEVKATAVKEAREKYGL
NT seq
2703 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccccaacgccatccagccgagcgagctcgaccagctcccggaccgcgacccc
gaggagaccgccgaatggcaggcctccctggacgccgttgccaaggcggccgggccgcac
cgtgccgcgtacctgatgcgccgcacgctggagcgcgccgagggcgccggcatcgcgctg
ccgaagctcctggagacggactacgtcaacaccatcccgaccgccgccgagcccgagctg
cccggcgacccggagatggaggcccgcatcaccgcgtggaaccgctggaacgcggccgcg
atggtgacccgcggcgccaagcacggcgtcggcggccacatcgccaccttcgcctccgcg
gcctggctgtacgagaccggcttcaaccacttcttcaagggcaaggagggggacggctcc
ggtgaccagctgtacatccagggccacgcctcccccggcatctacgcccgcgcgttcctc
gacggccgcctgaccgagcagcacctggacaacttccgtcaggaggccggcggcaacggc
ctgccgtcctacccgcacccgcggcgcctgccctggctgtgggagttcccgacggtgtcc
atgggcctcggcccgctgtcggcgatctaccaggcgcgcttcaaccgctacctgaccaac
cgcggcatcaaggacgtctccgcctcgcacgtgtgggcgttcctcggcgacggcgagatg
gacgagccggagtcgaccgcggccctcgcgctcgccgcccgcgagcagctggacaacctg
accttcgtcatcaactgcaacctgcagcgcctcgacggcccggtccgcgccaacttcaag
atcgtgcaggagctggaggcccagttccgcggcgccggctggaacgtcgtcaagacgctg
tggggttcggcgtgggacgagctgttccagctcgacaccaccggcgcgctcgtacgccgc
ctgcgtgaggtacccgacgcgcaggtgcagacgtaccagacccgcgacgccgcctacatc
cgcgaggacttcttcggcaaggacccggcgctcgccgagatggcgaagctgctgagcgac
gacaagatcctggagatcttccacgtctcgcgcggcggccacgagccccgcaaggtctac
gccgcgtacaaggccgccgtcgagcacaagggcgcgccgaccgtgatcctggcccagacg
gtcaagggccacaccctcggtgagggcttcgcctccaagaacgccaaccaccagatgaag
aagctctcggtggacgagttcaaggcgatgcgcgacctgctcggactgccgatcaaggac
agcgacttcgtcgacggcgtggtcccctacggccacccgggcgccgactcccccgaggtc
cgctacctccaggagcgccgcgccgccctcggcggtcccgccccggcccgccgtacgcac
ccgctgccggcgctgcccgccccggcggagaaggcgttcgcctccttcgacaagggctcc
ggctcccagaacgtggccaccaccatggccttcgtccgtctgatcaaggacctggtccgc
gacaaggagaccggcaagcgctgggtgccgatcgtccccgacgaggcgcgcaccttcggc
atggagtcgctgttcccgtcgctcggcatctactcgcccaagggccagacgtacgagccg
gtcgaccgcgaccagctgatgtactacaaggaggccaagaacggccagatcctcaacgag
gggatcaccgaggccggttcgatggccgacttcatcgccgcttcgacgtcgtacgcgacg
cacggcgaggcgatgatcccgttctacatcttctactcgatgttcggctggcagcgcacg
gccgaccagatgtggcagctcggcgaccagctcggccgcggcttcctcgtcggcgccacg
gccggccggacgaccctgaccggcgagggcctgcagcacgccgacggccactcccccgtc
atcgccgcgaccaacccggccgcgctgacgtacgaccccgccttcgcgtacgagatcgcg
gtgatcgtccgtgagggtctgcgccggatgtacggcgaggcgaagccgggcgaggaccag
gacgtcttctactacctgacggtctacaacgagccgctgccgcagcccgccaagccgcag
ggcctcggcatcgacgagggcatcgtcaagggtctgtaccgcttcaacacggcggagtcc
gcgggcgtcaccgtcccggccaacgccccgcgcatccagctgctcggctccggtacggcg
atccactgggccctggaagcccagaagctgctcgccgaggagtggggcgtggccgccgac
gtctggtcggccacctcctggacggagctgcgccgcgacgcgctggaggccgacgaggcc
ctcctgcgcggcgaggagcgcgtgccgtacgtccgccaggcgctgcagggcgccgagggc
ccggtgctggcggtctccgactacatgcgccaggtcccggaccagatcgcgcagtgggtc
gagcaggactggtcctcgctgggcgccgacggcttcggcctgtcggacacccgtgaggcc
gcccgccgccacttcggcgtcgacgccccgtcgatcgtcgtcgcggcgctggcccagctc
gcccggcgcggcgaggtgaaggccaccgcggtcaaggaggcccgggagaagtacggcctg
tag
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