Streptomyces actuosus: DMT42_26325
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Entry
DMT42_26325 CDS
T08084
Symbol
kgd
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sact
Streptomyces actuosus
Pathway
sact00020
Citrate cycle (TCA cycle)
sact00630
Glyoxylate and dicarboxylate metabolism
sact00785
Lipoic acid metabolism
sact01100
Metabolic pathways
sact01110
Biosynthesis of secondary metabolites
sact01120
Microbial metabolism in diverse environments
sact01200
Carbon metabolism
sact01210
2-Oxocarboxylic acid metabolism
Module
sact_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sact_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sact00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
DMT42_26325 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
DMT42_26325 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
DMT42_26325 (kgd)
Enzymes [BR:
sact01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
DMT42_26325 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
DMT42_26325 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
DMT42_26325 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
DMT42_26325 (kgd)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AWT45451
UniProt:
A0A2U9P8K3
LinkDB
All DBs
Position
complement(5636935..5640726)
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AA seq
1263 aa
AA seq
DB search
MSPQSPSNSSAPTTDADQAGKNPAAAFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYK
PGAPAAAGTAAAGAAETTSQTPQAQAPAPQAAAPAAPAQPAAQPAPAAAPAAKAPAQAQP
ARPAQAPAQPKAKAEPAKEAPAGPELVTLRGPSAAVAKNMDASLEMPTATSVRAVPVKLL
FDNRIVINNHLKRARGGKISFTHIIGYAMVQAIKAMPSMNWSYQLKDGKPTLVKPEHVNL
GLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARDNKLTMDDFTGVTVSLT
NPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLTSTYDHRV
IQGAASGEFLRQVANLLLGENGFYDDIFEALRIPYEPVRWLKDIDASHDDDVTKAARVFE
LIHSYRVRGHVMADTDPLEYKQRKHPDLDIVEHGLTLWDLEREFAVGGFAGKSMMKLRDI
LGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERPHSKMEREEQLRILRRLNAAEAFETF
LQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLANIVGKSYA
QIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLVANPSHLEAVDPVLEGV
ARAKQDIINKGGTDFTVLPVAIHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVINNQV
GFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVVIDLI
CYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDYQGQL
EKVFTEVREATAQPVPGDVQAPQDGFPVAVPTAVSSEVVKRIAESQVNIPDNITVHPRLL
PQLQRRAAMVEDGTIDWGMGETLAFGSLLLEGVPVRLAGQDSQRGTFGQRHAVIIDRSTG
EEYTPLQYLSEDQARLNVYNSLLSEYAAMGFEYGYSLARPDALVLWEAQFGDFVNGAQTV
VDEFISSAEQKWGQTSGVVLLLPHGYEGQGPDHSSARPERFLQLCAQNNMTVAMPTSPSN
YFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKAEEFTSGQFRPVIGDSSADPAAVRKV
VFCAGKVYYDLEAERVKRGVTDTAIIRIERLYPLPGAELQAEIKKYPNAEKYLWAQEEPA
NQGAWPFIALNLIDHLDLAVGADIPAGERLRRISRPHGSSPAVGSAKRHQAEQEQLVREV
FEA
NT seq
3792 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagcgcccctacgaccgacgccgaccaagcgggc
aagaaccccgctgccgcgttcggtgcgaatgagtggctcgtcgacgagatctatcagcag
tacctccaggacccgaattcggtagaccgcgcctggtgggacttcttcgccgattacaag
ccgggtgccccggctgcggcgggtactgcggccgcgggggccgcagagaccacctcccag
acgccccaggcccaggctccggccccgcaggccgccgcgccggccgctccggcgcagccc
gccgcgcagcccgccccggccgccgctcccgcggcgaaggcccccgcccaggctcagccg
gcgcgtcccgcacaggcgcccgctcagccgaaggcgaaggccgagccggcgaaggaggcc
cccgcgggccccgagctggtcacgctgcgcggtccgtccgccgcggtcgcgaagaacatg
gacgcctcgctggagatgccgacggccacgtccgtgcgcgccgtcccggtgaagctgctg
ttcgacaaccgcatcgtcatcaacaaccacctcaagcgcgcccgcggcgggaagatctcc
ttcacgcacatcatcgggtacgcgatggtgcaggcgatcaaggcgatgccgtcgatgaac
tggtcctaccagctcaaggacggcaagcccaccctggtcaagccggagcacgtcaacctc
ggtctcgccatcgacctggtcaagccgaacggcgaccgccagctggtcgtcgcggcgatc
aagaaggccgagacgctgaacttcttcgagttctggcaggcctacgaggacatcgtccgt
cgcgcccgcgacaacaagctgacgatggacgacttcaccggcgtcacggtctccctgacc
aaccccggcggcctcggcaccgtccactccgtgccgcgcctgatgcccggccagtccgtg
atcatgggcgtcggctccatggactacccggcggagttccagggcaccagccaggacacc
ctgaacaagctcggcatctcgaaggtcatgacgctcacgtcgacctacgaccaccgggtg
atccagggcgccgcctccggcgagttcctgcgccaggtcgcgaacctgctgctcggcgag
aacggcttctacgacgacatcttcgaggcgctgcgcatcccctacgagccggtccgctgg
ctcaaggacatcgacgccagccacgacgacgacgtcaccaaggccgcccgcgtcttcgag
ctgatccactcctaccgggtccgcggccacgtcatggccgacaccgacccgctggagtac
aagcagcgcaagcaccccgacctggacatcgtcgagcacggcctcaccctgtgggacctg
gagcgcgagttcgccgtcggcggcttcgccggcaagtcgatgatgaagctgcgcgacatc
ctcggcgtgctgcgcgactcgtactgccgcaccaccggcatcgagttcatgcacatccag
gaccccaagcagcgcaagtggatccaggaccgcgtggagcgcccgcactccaagatggag
cgcgaggagcagctgcggatcctgcgccgcctgaacgccgccgaggcgttcgagacgttc
ctgcagacgaagtacgtcggccagaagcgcttctcgctggagggcggcgagtccgtcatc
ccgctgctggacgcggtcatcgactccgcggccgagtcccgcctggacgaggtcgtcatc
ggcatggcccaccgcggccggctgaacgtgctcgccaacatcgtcggcaagtcgtacgcg
cagatcttccgcgagttcgagggcaacctcgacccgaagtcgatgcacggctccggcgac
gtgaagtaccacctgggcgccgagggcaccttcaccggcctggacggcgagcagatcaag
gtctcgctcgtcgccaacccctcgcacctggaggcggtggacccggtcctggagggcgtc
gcgcgcgccaagcaggacatcatcaacaagggcggcacggacttcaccgtcctgccggtg
gcgatccacggcgacgcggccttcgcgggccagggtgtggtggccgagaccctgaacatg
tcgcagctgcgcggctaccgcaccggcggcacggtccacatcgtcatcaacaaccaggtc
ggcttcaccgcggcccccgagtcctcgcgttcctccatgtacgcgacggacgtggcccgc
atgatcgaggccccgatcttccacgtgaacggcgacgacccggaggccgtcgtgcgcgtc
gcgcggctggcgttcgagttccgccaggcgttcaacaaggacgtggtgatcgacctcatc
tgctaccgccgccgcggtcacaacgagtcggacaacccggccttcacccagccgctgatg
tacgacctgatcgacaagaagcgctcggtgcgcaagctgtacaccgagtccctcatcggt
cgcggcgacatcaccctggaagaggccgagcaggcgctgcaggactaccagggccagctg
gagaaggtcttcaccgaggtccgcgaggccaccgcgcagccggtccccggtgacgtccag
gccccgcaggacggcttcccggtcgcggtgccgaccgcggtctcctccgaggtcgtcaag
cggatcgccgagtcccaggtcaacatcccggacaacatcaccgtccacccgcgtctgctg
ccgcagctgcagcgccgggcggcgatggtcgaggacggcacgatcgactggggcatgggc
gagaccctcgccttcggctcgctgctgcttgagggcgtgccggtccgcctggcgggccag
gactcccagcgcggcaccttcggccagcgccacgcggtcatcatcgaccgcagcaccggc
gaggagtacacgccgctgcagtacctctccgaggaccaggcgcgcctgaacgtctacaac
tccctgctgtccgagtacgcggccatgggcttcgagtacggctactcgctggcccgcccg
gacgcgctcgtgctgtgggaggcccagttcggcgacttcgtcaacggcgcccagacggtc
gtcgacgagttcatctcctccgccgagcagaagtggggccagacctccggcgtcgtcctg
ctgctgccgcacggctacgagggccagggcccggaccactcgtccgcgcgtcccgagcgc
ttcctccagctgtgcgcgcagaacaacatgacggtcgccatgccgacctcgccgtcgaac
tacttccacctcctgcggtggcaggtgcacaacccgcaccacaagccgctggtcgtcttc
accccgaagtcgatgctgcgcctgaaggcggcggcgtcgaaggcggaggagttcacgagc
gggcagttccgcccggtcatcggcgacagctcggccgacccggccgcggtccgcaaggtc
gtcttctgcgcgggcaaggtctactacgacctggaggccgagcgggtcaagcgcggcgtg
acggacaccgcgatcatccgcatcgagcgcctgtacccgctgccgggtgccgagctccag
gcggagatcaagaagtacccgaacgccgagaagtacctgtgggcccaggaggagccggcg
aaccagggtgcctggccgttcatcgccctgaacctgatcgaccacctggacctggcggtc
ggcgcggacatcccggcgggcgagcgcctgcgccgtatctcgcgtccgcacggctcgtcc
ccggccgtgggttccgcgaagcggcaccaggcggagcaggagcagctggtgcgtgaggtg
ttcgaggcctag
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