Streptomyces alboflavus: SMD44_07318
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Entry
SMD44_07318 CDS
T05221
Symbol
shc
Name
(GenBank) squalene-hopene cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
salf
Streptomyces alboflavus
Pathway
salf00909
Sesquiterpenoid and triterpenoid biosynthesis
salf01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
salf00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
SMD44_07318 (shc)
Enzymes [BR:
salf01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
SMD44_07318 (shc)
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
SMD44_07318 (shc)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
TED_complement
Prenyltrans
Motif
Other DBs
NCBI-ProteinID:
ARX87836
UniProt:
A0A1Z1WN15
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All DBs
Position
7991362..7993158
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AA seq
598 aa
AA seq
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MDAEDLLLRQFLGIQDESTTRAAALFIRGEQRDDGTWATFYGGPGELSATIEAYVALRLA
GDAPDAPHMARASAWIREQGGIASARVFTRIWLALFGWWKWDDLPELPPELLYFPKWFPL
NIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPSAPNPAKPLAPVASWDGIFQR
MDKALHLYHKVAPRGVRKAAMNSAARWIIERQENDGCWGGIQPPAVYSVIALHLMGYDLD
HPVLKAGLESLDRFAVWRKDGARMIEACQSPVWDTCLAAIALADAGVPADHPQLVKAADW
MLGEQIVRPGDWSVRRPGLTPGGWAFEFHNDNYPDIDDTAEVVLALRRVAHPDKPRLENA
IERGVRWNLGMQSKNGAWAAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVVEMLAWE
GRSHDPRTRRGVEWLLSEQEANGAWFGRWGVNYVYGTGSVLPALVAAGLPASHPAIRRAV
AWLESVQNDDGGWGEDLRSYRDEAWIGRGASTASQTAWALLALLAAGERDAKSVERGVDW
LTQAQTEDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVNGEPAVGGSGKGG
NT seq
1797 nt
NT seq
+upstream
nt +downstream
nt
atggacgccgaggacctgttgctccgtcagttcctgggcatccaggacgagtcgaccacc
agagccgccgccctcttcatccgcggcgagcagcgcgacgacggcacctgggccaccttc
tacggcggccccggcgaactctccgccaccatcgaggcgtatgtggcgctgcgccttgcg
ggggatgcccccgacgcgccgcacatggccagggcgtccgcctggatccgggagcagggc
ggcatcgcgtcggcccgggtcttcacccgcatctggctcgccctcttcggctggtggaag
tgggacgacctgcccgagctgccgcccgaactcctttattttcccaagtggttcccgctc
aatatctatgacttcggctgctgggcgcggcagaccatcgtgccgctcaccattgtctcg
gccaagcgcccggtgcgccccgcgcccttcccgctggatgagctgcacaccgacccgagc
gcccctaatcccgccaaaccccttgccccggtggcgagttgggacggcatcttccagcgc
atggacaaggcgctgcacctctatcacaaggttgcgccacgcggtgtgcgcaaggccgcg
atgaacagcgccgcacgctggatcatcgagcggcaggagaacgacggctgctggggcggc
atccagccgcccgccgtgtactccgtgatcgcgctgcatctgatgggctacgacctcgac
cacccggtcctcaaggcgggcctcgaatccctggaccggttcgccgtgtggcgtaaggac
ggcgcgcggatgatcgaggcctgccagtcgccggtgtgggacacctgcctcgcggccatc
gccctcgccgacgccggggtgcccgccgaccatccgcagctggtcaaggccgcggactgg
atgctgggcgagcagatcgtgcgccccggcgactggtcggtgcgcaggccgggtctgacc
cccggcggctgggccttcgaattccacaacgacaactaccccgacatcgacgacaccgcc
gaggtcgtcctcgcactgcgccgggtcgcgcacccggacaagccgcgcctggagaacgcc
atcgagcgcggtgtgcgctggaacctcggcatgcagtcgaagaacggcgcctgggccgcc
ttcgacgtcgacaacaccagccccttccccaaccgcctgccgttctgcgacttcggcgag
gtcatcgacccgccctccgccgacgtcaccgcgcacgtcgtggagatgctcgcctgggag
ggcaggtcccacgacccgcgcacccggcggggcgtggagtggctgctctccgaacaggag
gcgaacggcgcctggttcgggcgctggggcgtcaactacgtctacggcaccgggtcggtg
ctgcccgcgctcgtcgccgccgggctgcccgcctcgcacccggcgatccggcgcgcggtc
gcctggctggagtcggtgcagaacgacgacggcggctggggcgaggacctgcgctcgtac
cgcgacgaggcgtggatcgggcgcggcgcgtccaccgcgtcccagaccgcctgggcgctg
ctcgcgctgctcgcggcgggggagcgggacgccaagtccgtggaacgcggcgtcgactgg
ctgacgcaggcgcagaccgaggacggctcctgggacgagccgtacttcaccggtaccggc
ttcccctgggacttctcgatcaactaccacctctaccggcaggtcttcccgctgaccgcg
ctcggccggtacgtgaacggggagcccgccgtcggcggctccggcaaggggggctga
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