Salvelinus sp. IW2-2015 (Arctic char): 111950321 Help Entry 111950321         CDS       T05762                                  Name (RefSeq) ryanodine receptor 1-like   KO K04961   ryanodine receptor 1 Organism salp  Salvelinus sp. IW2-2015 (Arctic char) Pathway salp04020   Calcium signaling pathway salp04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:salp00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     111950321    04020 Calcium signaling pathway     111950321  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:salp01009]     111950321   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:salp04147]     111950321    04040 Ion channels [BR:salp04040]     111950321 Protein phosphatases and associated proteins [BR:salp01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      111950321 Exosome [BR:salp04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    111950321 Ion channels [BR:salp04040]  Voltage-gated cation channels   Ryanodine receptor    111950321 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 Ins145_P3_rec MIR SPRY RIH_assoc Ion_trans EF-hand_7 EF-hand_8 Motif Other DBs NCBI-GeneID:  111950321 NCBI-ProteinID:  XP_023823574 LinkDB All DBs Position LG23:39302967..39377239 Genome browser AA seq 5085 aa AA seqDB search MAEGGDGEEEIQFLRTDDQVVLQCTASILKEQIKLCLSCEGFGNRLCFLETTSNAQNVPP DLAICCFILEQSLSVRALQEMLSNTMELNEAVDLDKWSSQGGGHRTLLYGHAILLKHTHS SMYLSCLTTSRSLTDKLAFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRVGDDLILVSV SSERYLHLSYASGDLMVDASFMQTLWTMSPVMSGCELAEGFLTGGYVLRLFHGHMDECLA IPAAEQGDNQRRIAHYEGGAVCSHARSLWRLEPLRIGWSGGHMKWGQSFRVRHITTGRYL CLDEEKGLLVVDPEKANAKMSAFCFRISKEKIEVAQKRDVEGMGTPEIKYGESMCFVQHV STGLWLTYASVDAKSARLGPLKRKAILHKEGHMDDALTVARSQTEEFQAARMIYNTAGLF TQFIKALDSLSGKNKSSSGPPSLPMDSVALSLQDLIFYFRPPEEELEHEEKQTKLRSLKN RQNLFQEEGMITLVLDCIDRLNVYNTAAHFSEFAGEEAAESWKEIVNLLYELLASLIRGN RANCALFCDNLDWLVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKH GRNHKVLDVLCSLCVCNGVAVRSNQNLITENLLPGRDLLLQSNIINYVTSVRPNIFLGTC EGSTQYKKWYFEVMVDYVEPFLTAQAFHLRVGWALTEGYSPYPGGGEGWGGNGVGDDLYS YAFDGLHLWSGRVLRHVASPNMHILAADDVVSCCLDLSVPSISFRINGHPVQGMFENFNL DGLFFPVVSFSAGVRVRFLLGGRHGDFKFLPPPGYAPCYEAVLPKDRLRIEPIKEYKHDF NGVRNLLGPTQSLSHTAFTPCPVDTVQIVLPPHLERIREKLAENSHELWAATRIEQGWTY GSFRDDNKKLHPCLVDFQSLPEPEKNYNLAMSGETLKTLLALGCHVGMGDEKAEENLKNI KMPKTYMMSSGYKPAPLDLNHVKLTPNQTNLVERLAENGHNVWARDRVHQGWTYSIVQDI MSKRNPRLVPYNLLDEKTKKTNRDTVCAAVRTLIGYGYNIEPPDQESSGNGEGHSRGNKI RVFRAEKSYAVTQGKWYFEFEAVTVGDMRVGWARPSVRADTELGADELAYVFNGFKAQRW HVGNEPFGRSWLPGDVVGCMIDLVEQNIFFTLNGEMLISDSGSEMAFKDIDTGDGFIPVC SLGLSQVGRLNLGQNVSSLRYFTICGLQEGFEPFAINMKRDITMWFSKSLPQFIPVPTEH PHIEVSRVDGTVDSAPCLKLTHKTFGSQNANTDLLFLRLSMPVEFHETFKVMAGTTPLTR ALTIPEDEVLEVDPDSDFEVLKKSASRTEKEEEKEPSVPKEISVNGRENVKDASTEKSKK KGFLFKAKKAAFTPPPVVPTMPRLMEEVVPDDRDDDDIILNTTTYYYSVRVIAGQEPSGV WVGWITPDYHQYDLHFDLSKVRNVTVTVGDDKGNIHDSMKRSNCYMVWGGEFSSSQQTRV SQEDFVIGCLIDLDTGLMTFTANGKEINTFYQVEPNTKLFPAVFVLPSSQNMLQVELGKL KNIMPISAAMFRSERRNPVPQCPPRLDVQMLTPVIWSRMPNHFLSPETGRVNERHGWMVE CREPLTMMALHIPEENRCIDVLELSERMDLLKFHYHTLKLYGSVCALGNNRVAHALCSHV DESQLFYAIENTYLPGPMRSGYYDLLISMHLESAKRNRLMTNKEFIVPMTDETRSINLYS DTDNSHALPGVGLTTCLRPKLHFSPTGFVGTDLDIYTLSPFIPLQVLKAKALTMLTEAVQ DGGQAMRDPVGGSVEFHFVPILKLISTLLIMGVFENEDVKHILKMIEPTVFSGEAEAAAE EAEATAKGAGSQTLALKEGGEEVKEEEEGAVESGHETEMEDEGMGEEDEELEAELEELVE KEEEEDGEKVDGEKGAEETEKEATPGEADEQVGLEEGLLHMKLPESVKLQMCTLLQYFCD CELRHRVEAIIAFSDQFVSQVQANQRARYNELMLAFTMSAAETARKTREFRSPPQEQVNM LMNFKSIAEDEECPVPDEVRDALLSFHKNLLAHCGVHIEEEEVEEELDMSLKGRLFRILD KLRHLRKKKVEEEPEAVEETKPSTLQELISHTMIHWAQESFIQNPELVRLMFSLLHRQYD GLGELIRALPKAYTINAISIKDTMDLLECLGQIRSLLIVQMGPEEERLMIQSIGNIMSNK VFYQHPNLMRALGMHETVMEVMVNVLGGGDSKEIRFPRMVTNCCRFLCYFCRISRQNQRS MFDHLSYLLQNSGIGLGMRGSTPLDVAAASCIDNNELALALQEQDLEKVVKYLAGCGLQS CPQLLAKGYPDIGWNPCGGEKYLDFLRFAVFVNGESVEENANVVVRLLIRRPECFGPALR GEGGNGLLAAIEEAIKISEDPARDGPTVKKDRRFPGMFPGGEEQHEENKVHLGNAIMSFY SALIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPMEDLVGVISLSVQIPDFGKDNSVI EPKMSSSFVPDHKAPMVLFLDRVYGIDNQDFLLHVLEVGFLPDMRAAASLDTAAFCTTEM ALALNRYLSLAVLPLITKCAFLFAGTDHRAIMIDSMLHTIYRLSRGRAFTKAQRDVIEEC LMALCKNLRPSMLQHLLRRLVFDVPILNEYAKMPLKLLTNHYERCWKYYCLPNGWGNFGV SSEEELHLTRKLFWGIFESLAHKKFDAELFKIAMPCICAIAGAIPPDYVDASYSSKTEKK ALVDAEGNFDPKPVETTNTIIPERLDGFINRYAEYTHDKWAFEKIQNNWTYGEMLDENSK THPMLRPYKTFSEKDKEIYRWPIKESMKAMIAWEWTLDQTREGDEAKTEQKKAARKISQT AQATYDPSHGYSPQPIEISHTALSRELQSMAEQLAENYHNTWGRKKKMELQSKGGGAHPL LVPYDTLTAKEKARDREKAHELLKFLQLNGFAVTRGMKDMESDISSIEKRFAYGFLQKLL KWMEIAQEFIAHLEAVVSSGRVEKSPHEQEIKFFAKILLPLINQYFKNHCLYFLSTPAKV LGSGGHSSNKEKEMIASIFCKMAALVRHRVSLFGNDAAAIVNCLHILARSLDARTVMKSG PEIVKAGLRSFFEGAADDIEKMVENLKLGKVSKGNQQVKGVSQNINYTTIALLPVLTSLF DHISQHQFGDDVMLDDLQMSCYRIMCAIYSLGSVKNPHVERQRPALGECLAHLAAAMPVA YLEPHLNEYNAFSVYTTKTPRERAILGLPNEVQELCQDIPELDILLKEIGDLAESGARYT EMPHVIEITLPMLCNYLPRWWERGLENFPELEGQICTDVTSDQLNQLLGSIMKIVVNNLG IDEASWMKRLAVFSQPIVSRARPEMLKSHFIPTMEKLKKRTGKVVAEEDHLRMEGKAEGD EEEGTIRDEFAVLCRDLYALYPLLIRYVDNNRARWLTCPDPDAEELFRMVGEVFIFWSKS HNFKREEQNFVVMNEINNMSFLTADSKSKMSKGSDSEAGGSDVERTKKKRRGDRYSVQTS LIVAALKKMLPIGLNMCSPADHELINLAKIRYSLRDTDEEVREFLQNNLHLQGKVENPSM RWQMSLYKEMAGKAEDADAPEKVVKRVQEVSAVLYHIEVTEHPFKSKKMVWHKLLSKQRR KAVVACFRMTPLYNLPRHRASNMFLEGYKRNWIHTEGYSFEDRMIDDLSKAMEQEGEEEE ETETKPDPLHQLILHFSRTALTEKSKLDTDYLYMAYADIMAKSCHIGEEDEGGEEVEEGA EDEMSFEEKEMEKQRLLYQQSRLHNRGAAEMVLQMISACKGETGCMVSSTLKLGISILNG GNVEVQQKMLEYLKDKKDVGFFLSVQALMQTCSVLDLNAFERQNKAEGLGMVSEEGTSEK VMADDEFTCDLFRMLQLLCEGHNNDFQNYLRTQTGSTTTINIIICTVDYLLRLQESISDF YWYYSGKDIIDEPGKKNFSKAMIVAKQIFNSLTEYIQGPCTGNQQSLTHSRLWDAVVGFL HVFAHMMMKLAQGKDSSQIGLLKELLDLQKDMVVMLLSLLEGNVVNGTIARQMVDMLVES SSNVEMILKFFDMFLKLKDIVASDAFRDYVTDPRGLISKKDFQKAMDSQKQYSPSEIQFL LSCSEADENDMINFEEFADRFQEPAKDIGFNIAVLLTNLSEHVPHDLRLKNFLEQAESVL NYFRPFLGRIEIMGASRKIERIYFEISEVNRTQWEMPQVRESKRQFIFDVVXEGXESEKM EMFVNFCEDTIFEMNIASQISEQEEEXXEEDDDXPAEGGXXAGGGGGGDEEGNGEEGEPE SSSAFADFINSLLNFLSIFTFRNLRRQYRRVRKMTIKQIVVGLATFFWTILIGILHFIYS VCKGFFLLIWQTLFGGGLVEGAKNITVTEILASMPDPTQDEVHGDLPGEPRTGEEQEAGG VTDQMDTGGGEEEEVDNQDKEGGGPPRIDAPGGLGDMGIEATVEPPTPEGTPLTRRKQQP EEGAAAAADGQAAEPAPAPAIEEPPPEPEKADTENGEKAEKEAETKEEEKQEEPKEKKAK DKKNKKQHREQGFQLWTELDIQRNKFLNYLSRNFYNLRFLALFIAFALNFILLFYKVSDS PPGEGDEVEGSGMFEGSGVGALFEGSGLFEGSAEEMEGSGGDEGGDDEEEEEGPVYFFLE ESTGYMQPTLTFLAALHTVIAFLCIIGYNCLKIPLVIFKREKELARKLEFDGLYITEQPE DDDIKGQWDRLVLNTPSFPNNYWDKFVKRKVLDKYGDIYGRERIAELLGMDLASLDVSQQ TDKKPEEPDNSTLAWCTSIDFKYQIWKCGVVFTDGTFLYLCWYTIMSLLGHYNNFFYACH LLDIAIGVKDLRTILSSVTHNGKQLMMTLGLLAVVVYLYTVVAFIFFRKFYNKSEDEDEP DMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDVYELYRVVFDITFFFFVIVILLAII QGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFL MYLINKDETEHTGQESYVWKMYQERAWDFFPAGDCFRKQYEDQLA NT seq 15258 nt NT seq  +upstreamnt  +downstreamnt atggcggaaggaggagatggagaggaggagattcagttcttacgtacggatgaccaggtt gtgctacaatgcactgcctccattctgaaagaacagatcaaactgtgtctttcatgtgag ggctttgggaaccgcctctgcttcctggagaccacctccaatgctcagaatgtgccacct gatttggcgatctgctgcttcatcctggagcaatccctgtcggtacgagccttacaggag atgctgtccaacaccatggagctcaatgaggcagtcgatttggacaaatggtcatctcaa ggagggggccaccgtaccctgctgtatggccatgccatcctactgaagcacactcactcc agcatgtacctcagctgtttgactacctcaaggtcactcacagacaaactggcctttgat gtgggcttacaggaagattccaccggggaggcgtgctggtggaccattcaccctgcgtcc aagcagaggtcagagggagaaaaggtcagggtgggagatgatctcatcctggtcagcgtg tcctctgagagatacctgcatctctcctatgccagtggtgatctcatggtggacgcctcc ttcatgcagacgctgtggaccatgagccctgtgatgtctggctgtgagcttgctgaaggc tttctgactggaggctatgttctgagactgttccatggtcacatggacgagtgcttggct atccctgctgccgagcaaggagacaaccagcgaagaattgctcattatgaagggggtgct gtctgtagccatgcccggtcactatggagactagaacccctccggattggatggagtgga ggtcacatgaaatggggccagtcgttccgagtgcgtcatataaccacaggccgctatctc tgcctggatgaagagaaaggactgctggtggtggaccctgaaaaagccaacgccaagatg tcagccttctgcttcagaatctccaaggaaaagatcgaggtggctcagaaacgagatgtg gagggcatgggcacaccagagattaagtatggggagtccatgtgttttgtacagcacgtc tccactggcctctggcttacatacgcctctgtcgatgccaagtccgctcgcctgggacct cttaagaggaaggccatccttcataaggagggccacatggacgatgccctgaccgtggcc cgctcccagacagaggagttccaggctgcccgtatgatctacaacacagcaggcctcttc actcagttcattaaagcgctggactctctgagtgggaagaacaagtcttcttcaggcccc ccgtctctccccatggactcagtggccctctccctgcaggacctcatcttctacttccgg ccccctgaggaggagctggagcacgaggagaagcagaccaaactacgctccctcaagaac agacagaacctcttccaagaggagggcatgatcaccctggtgctggactgtattgacaga ctcaatgtctacaacacggcggcccacttctccgagtttgcaggggaggaagctgccgag tcttggaaggaaatcgttaatctcctgtacgagctgctggcctctctcatcagaggtaac cgggccaactgtgctttgttctgtgataacctggattggctggtcagcaaactggaccgt ctggaggcctcctcaggcatcctggaggtgctgtactgcgttctgattgagagtccagag gtcctgaacatcatccaggagaaccacattaaatctatcatttctctactggataagcat ggacgcaatcacaaggtgttggatgtgctctgctctttgtgtgtgtgtaacggtgtggct gtaaggtccaatcagaatctcatcaccgagaatctgcttccaggtcgcgacctcctcctg cagtccaacatcatcaattatgtcaccagtgtgagacccaacatcttcctcggaacctgt gagggatccacacagtataagaagtggtattttgaggtgatggtggattatgtagagccc ttcctgaccgcccaggccttccacctgcgtgtgggctgggctctgaccgagggctacagc ccctaccctgggggtggtgagggctggggcggcaacggggttggcgacgacctttactcc tacgcctttgatggactccacctgtggtcaggacgagtcctccggcatgtcgcctcccct aacatgcacatcctagcggcagacgatgtggtcagctgctgcctggatctgagcgtgccc agcatctcgttccgtatcaacgggcacccggtgcagggcatgtttgagaacttcaacctg gacggcctcttcttccctgtcgtcagcttctctgcaggcgtcagggttcgttttctcctg ggagggcgtcatggggacttcaaattcctcccaccgccaggctatgccccatgctatgag gctgtgctgcccaaggaccgactgcgtattgagcccatcaaggagtataagcatgatttc aatggtgtccgcaatctgttggggcctacacagtccctctcgcacaccgccttcaccccc tgccctgtggacacagtacagattgtgcttccgcctcacttggagcgcattcgggagaag ctggcggaaaacagccatgagctatgggccgccactcgcattgaacaaggatggacctac gggtcgttccgagatgacaacaagaaactgcacccctgtctggtagatttccagagcctg ccagagccagagaagaattacaaccttgcaatgtctggagaaacactcaagactctgctg gcgctgggctgtcatgtgggcatgggggatgagaaagcagaggagaacctgaagaacatc aagatgcccaaaacgtatatgatgagtagtggatacaagcctgcccctctggacctcaac catgtcaagctgacacccaaccagaccaacctagtggagagactggcagagaatgggcac aacgtgtgggctcgtgacagggtccaccagggatggacctacagcattgtacaggacatt atgagcaagcgcaacccgcgcctggtgccgtacaacctgctggacgaaaagaccaagaag accaacagagacactgtctgtgcagctgtccgcactctcatcggctacggttacaacatt gagccacctgaccaggagagcagtggtaatggggaaggtcattcccgtggaaataagatc cgtgtgttccgggctgagaagtcatacgcggtgacccaggggaagtggtactttgagttt gaggctgtcaccgtgggggatatgagagtgggttgggcccgacccagtgtccgcgcggac acagagctgggggcggatgagctggcctatgtcttcaatggtttcaaggctcagcgctgg catgtgggcaatgagccgtttggtcgtagctggttgccaggtgacgtggtgggctgtatg atcgacctggtagagcagaacatcttcttcaccctgaacggagagatgctgatcagcgac tctggctctgagatggccttcaaggacatagacacaggagatggctttatccctgtgtgt agtctgggcctgtctcaggttggccggctcaacctgggccagaacgtcagcagcctgcgc tacttcaccatctgtggcctgcaggagggctttgagcctttcgccatcaacatgaagcga gacatcaccatgtggttcagcaagagcctgccccagttcatccctgttcctacagaacac cctcacattgaggtgtcccgtgtggatgggacagtggacagcgctccgtgtctgaagctg acccacaagacctttggctctcagaacgccaacacagacctgctgttcctgaggctcagc atgcccgtggagttccacgagacctttaaggttatggccgggaccacccccctcacccga gctctgaccatccctgaggacgaggttctggaggttgaccccgactctgactttgaggtg ctgaagaagtctgccagccgcacagagaaggaggaggagaaggagccctctgtgcctaag gagatctccgtcaacggaagagagaatgtgaaagatgcctctacagagaagagcaagaag aaggggttcctgttcaaggccaagaaggcagctttcactccgccccctgttgttcccacc atgccccgcctgatggaggaagttgtaccagacgatcgagatgacgacgacatcatcctc aacaccaccacatactattattcagtgcgagtgattgcgggacaagaacccagcggtgtg tgggtgggctggatcaccccggactaccaccagtacgacctgcactttgacctcagtaaa gtcagaaatgtcactgtcaccgtgggagatgacaaaggcaacatccatgacagtatgaag cgcagtaactgctacatggtgtggggaggggagttcagcagctcccagcagacccgtgtc agtcaggaggactttgtgattggctgccttattgacctggacactggcctcatgactttc acagccaacgggaaagagatcaacaccttctaccaggtggagcccaacacgaaactgttc ccagctgtctttgtcctgccctccagtcagaacatgctccaagtggagctgggcaagctc aagaacatcatgcccatctcggcagccatgttccgcagtgagcgtaggaacccggtcccc cagtgtcctccgaggctggacgtccagatgctgaccccagtcatctggagccgtatgccc aaccacttcctgtccccagagacgggccgtgtgaacgagaggcacggctggatggtggag tgtagagagcctctcaccatgatggccctgcacatccctgaggagaacagatgtattgac gtcctggagctgtcggagcgtatggacctgctgaagtttcactaccacactctgaaactg tacggctcggtctgtgctctggggaacaaccgcgtggctcacgccctctgcagtcatgtt gatgagtcccagctgttctacgccatagagaacacctacctgcctggaccaatgaggagc ggctactacgacctgctcatcagcatgcacctggagtcggccaagaggaaccgcctcatg accaacaaggagttcatcgtgcccatgacagacgagacgcgcagcatcaacctctactcc gacactgacaactcccatgctttaccaggggtgggcctcactacctgcctgcgccccaaa ctccacttctcccctactggctttgtgggtacagacctggacatctacaccctcagccca ttcatccccctacaggtgctgaaggcgaaggccctgaccatgctgacagaagctgtacaa gacggtggtcaggccatgagggatcctgtaggaggcagtgttgagttccactttgtcccc atcctcaagctcatcagcaccctgctcatcatgggcgtgttcgagaatgaagatgtcaag cacatcctgaagatgatagagcccacggtgttcagtggagaggcagaggctgctgcagaa gaagcagaagccacagccaagggcgcggggagccaaacgctggcgctcaaagaagggggg gaggaggtgaaggaagaagaggagggagcagtggagagcggacatgaaacagaaatggag gacgaggggatgggtgaggaagatgaggaactggaggcagagctggaggagctggtagaa aaagaggaagaggaggacggagagaaagtggatggagagaaaggtgctgaggagacggag aaggaggcgacgcctggagaggcagacgaacaagtaggtctggaagagggattactgcac atgaagctgccagagtctgtcaagctacagatgtgcactctgcttcagtatttctgtgac tgtgagttgcgccacagggtggaggccatcatagccttctcagaccagtttgtgagccag gtgcaggccaaccagagagcccgctacaacgagctcatgctggcgttcaccatgagcgct gccgagactgcccgcaagacccgcgagttccgctccccaccgcaggagcaggtcaacatg ctgatgaactttaagagcattgcggaggatgaggagtgtcctgtgcctgacgaggtccgc gatgccctgctgtcttttcacaagaacctacttgctcactgcggtgtacacattgaagag gaagaggtggaggaggagttggatatgtctctcaaaggacgactcttcagaatattggac aagttgaggcacctccgcaagaagaaggtagaggaggagccggaagctgtagaagagacc aaacccagtactctccaggagctcatctcccacactatgatccactgggcccaggaatcg ttcatccagaaccctgagctggtgcgtctgatgttcagcctgctgcaccgtcagtatgac gggctgggggagctgatccgggccctgcccaaggcctacaccatcaacgccatctccata aaggataccatggacctgctggagtgcctgggacagatccgctcgctgctcatcgtccag atgggccccgaggaggagagactcatgatccagagcatcggaaacatcatgagcaacaaa gtgttttatcagcaccccaacctgatgcgagccctgggcatgcacgagactgtcatggag gtgatggtcaacgtgctgggtggtggcgactccaaggagatcagattccctcgcatggtc accaactgctgtcgtttcctgtgctacttctgtcgtatcagtcgccagaaccagcgttcc atgttcgaccacctcagctacctgctacagaacagtggcattggccttggaatgcgtggc tccacccctctagatgtggctgcagcatcctgcattgacaacaatgagctggctctggct ctacaggaacaagacctggagaaggtggtgaagtacctcgcaggctgtgggctccagagc tgtccccagctcctggctaagggttaccctgacattggctggaacccgtgtggcggggag aaatacctggacttcctccgcttcgctgtcttcgtcaatggagagagcgtagaggagaat gccaacgtggtggtgcgtcttctgatccgtcggccagagtgttttggcccggccctgaga ggagagggtgggaacggcctgctggctgctatagaggaggccatcaagatctctgaagat cctgccagggacggccccactgtgaagaaagacaggcgcttccccggcatgttccctggt ggggaggagcagcatgaggagaacaaggttcacctggggaatgccatcatgtccttctac tcagctctcattgacttgctgggacgctgcgctccagagatgcatttgatccaggctggg aagggcgaggctctgaggatcagggccatcctgaggtccctggtgcctatggaggacctg gtgggagtcatcagtctgtctgtccagataccagactttggaaaagataacagcgtcatt gaacccaagatgtcttccagttttgtgccggaccacaaggctcccatggtgctgttcctt gacagagtgtatggtattgacaaccaagacttcctgcttcacgtgctggaggtaggcttc ctgcctgacatgagggcagctgcttctctggacacagcggctttctgcaccacagagatg gccctggctctgaaccgctacctctctctggccgtgctgcccctcatcaccaagtgtgcc tttttgttcgctggcactgaccaccgggccatcatgatcgactccatgctgcacaccatc taccggctgtcccgcggacgagccttcactaaggcccagagagatgttatagaggagtgt ctcatggctttgtgcaagaatctgcggccatccatgttacaacacctgttgagaaggctg gtatttgacgtgccaattctcaatgaatatgccaaaatgccactcaagcttttgaccaat cactatgagcgttgttggaagtactattgcctgcccaacggctggggcaactttggagtg tcgtcagaggaggagctgcatctcacccgcaaactcttctggggcatctttgagtccctg gcccacaagaaatttgatgctgagctgttcaaaattgccatgccgtgcatatgcgccatt gctggggccatccctccagattatgtagatgccagctactcctccaagactgagaagaaa gctttggtggatgcagagggaaactttgatcccaaaccagtggagaccacaaatactatc atccctgagagattggatggcttcatcaacagatacgctgagtacacacatgacaagtgg gcttttgaaaagattcagaataactggacgtatggagagatgttggatgaaaattcaaaa actcaccccatgctccgaccgtacaaaacattctccgagaaggacaaggagatctaccgt tggcccatcaaagagtccatgaaggccatgattgcatgggagtggactctggatcaaacg agggaaggagatgaagccaagactgagcagaagaaggcagctcggaagatctctcagact gcgcaggcaacatatgaccccagccatggctacagtccccaaccaattgaaatatcccac acggcactgtcaagagagctgcagtcaatggcagaacaacttgcagagaactatcacaac acctggggtcgaaagaagaagatggagctgcagtccaaaggaggaggcgcccaccctttg cttgtgccctatgacaccctgacagcaaaggagaaggcacgagacagggaaaaggctcat gagcttctcaaatttcttcaactcaatggatttgcagtcaccaggggaatgaaagacatg gagtcagacatctcatctatcgagaagcgctttgcctatggtttcctgcagaagctgttg aagtggatggagatcgcccaagagttcatagctcatcttgaggctgtggtgagcagtggt agagtggagaagtcgcctcatgagcaggagatcaaattctttgcmaagatcttgttgccc ctgatcaaccagtactttaaaaaccactgtctgtacttcctgtccacaccggccaaagtc ctgggtagtggaggacattcctctaacaaggagaaagagatgattgccagtatcttctgt aaaatggctgctctggtgagacacagagtttctctcttcgggaatgatgctgctgctatt gtcaactgtcttcacatcctggcacgatcactcgatgcaaggacggtgatgaagtctggg cctgagattgtgaaggcagggctccggtcgttctttgagggtgcagctgatgatatcgag aagatggtggagaacctcaaactgggcaaggtgtctaaaggcaaccagcaggtgaaaggc gtgtcccagaacatcaactacaccaccattgctctgctcccagtcctcacctccctgttc gaccacatctctcagcaccagtttggagatgatgtcatgctggatgatctccagatgtcg tgttaccgcatcatgtgcgccatctactccctgggcagtgtcaagaaccctcatgtggag aggcagaggccagccctgggagagtgtctggcccatctggcggctgctatgcctgtggcc tacctcgagccccatctcaatgagtacaatgccttctctgtttacaccaccaagaccccc agagaaagagccatcttgggtctgcccaacgaggtccaggagttatgccaggacatacca gagctagacattctgctgaaagagatcggggacttggcagagtcaggtgcccgttacact gagatgccccatgtgatcgagatcactctgcccatgctgtgtaactacctgccccgctgg tgggagagaggattagagaacttccctgagctggagggccagatctgcaccgacgtcacc tctgaccagctcaaccagctgctgggcagcatcatgaagatcgtggtcaacaacctgggc attgacgaggcctcctggatgaagaggctggctgtcttctcccagcctattgtgagcagg gccaggccagagatgctcaagtcccatttcatccccaccatggagaagctgaagaagagg acagggaaggtggtggccgaggaggaccacctgcgtatggaggggaaggccgagggggac gaggaggagggcaccatcagggatgagtttgctgtgctctgcagggacctgtacgccctc taccctctcctcatccgctatgtggacaataacagggcgaggtggttgacatgcccggac ccagatgcagaggagctcttcagaatggttggagaggtcttcatcttttggtccaaatct cataacttcaagcgagaggagcagaactttgtggtgatgaatgagattaataacatgtct ttcctcactgctgacagcaagagcaagatgagcaagggcagcgactcagaggctggtggc tcagacgtggagcgtaccaagaagaagagacggggagaccgttactcggtgcagacgtca cttattgtggctgccctgaaaaagatgctccccatcggcctcaacatgtgctcccctgca gatcatgagcttatcaacctggccaagatccgatactcgttgagggacaccgatgaggaa gtaagggagttcttgcaaaacaacctgcatcttcaaggcaaggtagagaacccgtccatg cgctggcagatgtccctgtataaggagatggcagggaaggctgaggatgctgacgctcca gagaaagtggtgaagagggtgcaggaggtgtcagctgtgctctatcacattgaggtgacg gagcaccccttcaaatccaaaaagatggtgtggcacaaactgctgtccaagcagagacgc aaggctgtggtagcctgctttaggatgacgccactctacaacctacccaggcatagagct tccaatatgttcttggaagggtacaaacgcaactggatccatactgagggctactccttt gaggacagaatgatagacgacttgtctaaagccatggagcaagaaggagaggaggaggaa gagacggagaccaagccagacccccttcaccagctcattttgcatttcagccgtactgct ctcacagaaaagagtaaacttgatacagattacctatatatggcatacgctgatattatg gcaaagagctgccacattggtgaggaggacgaagggggagaggaggtggaggaaggggct gaggatgagatgtcctttgaggaaaaagagatggagaagcagaggctcctataccagcag tcccgtctccacaaccgtggggcggctgagatggtgctgcagatgatcagtgcttgcaaa ggtgagactggctgcatggtgtcctccactcttaaactgggcatctccatcctaaacggt ggtaacgttgaggttcaacagaaaatgcttgagtacctgaaggataagaaggacgttggg ttctttttgagtgtccaggctctaatgcagacgtgcagtgtcctggacctgaatgccttt gagagacagaacaaggcagaggggctgggtatggtgtcggaggagggaacaagtgagaaa gtcatggcggatgatgagtttacctgtgatctgttccgcatgttgcagctgctctgtgag ggccacaataacgatttccagaactacttgcggacacagacaggcagcaccaccactata aacatcatcatctgcactgtggattacctcctccgactgcaggagtcaatcagtgatttc tactggtattactctgggaaagatatcattgatgagccaggcaagaagaacttctccaag gccatgatagtggctaagcagatcttcaacagtctgactgagtacatccagggtccgtgt acaggcaaccagcagtccctgacccacagcaggctgtgggatgcagtggtgggcttcctc cacgtctttgcccacatgatgatgaagctggcacagggtaaagattccagccagattggc ctgctgaaggagctactggacctccaaaaagacatggtggttatgctgctctctctactg gagggtaatgttgtgaatggcaccattgcccgtcagatggtggacatgctggtggaatcg tccagcaacgtggagatgatcctcaaattctttgacatgtttctcaaactgaaggacatt gtggcgtcagacgccttccgtgattacgtgaccgacccccgagggttgatctctaagaag gactttcagaaggccatggacagccagaaacagtactctccctctgagatccaattcctg ttgtcctgctcagaggccgatgagaatgacatgatcaactttgaggagtttgccgaccgc ttccaggagccagctaaagacattggatttaacattgcagtgttgctgaccaacctgtct gaacatgtccctcatgacctcaggctgaagaacttcctagagcaggcagagagtgtactc aactacttccgccccttcctgggccgtatagagatcatgggtgccagcaggaagatmgag cgtatttactttgagatcagcgaggtcaaccgcacacagtgggagatgcctcaggtcaga gagtccaaacgacagttcatctttgatgtggtyamtgagggggscgagtcggagaagatg gagatgtttgtcaacttctgcgaggacacyatctttgagatgaacatygcctcccagatc tcggagcaggaggaggagragraggaggaggatgatgatgakccrgctgaaggaggarct gakgcaggaggaggwggaggkggagatgaagarggcaatggagaggaaggagagccagag tccagctctgcctttgcagacttcatcaacagcttattgaacttcctgagtatcttcacc ttccgtaacctgcgcaggcagtaccgcagagtgaggaagatgaccatcaagcagatagtg gtgggtctggccaccttcttctggactatcctcattggcatcctgcacttcatttacagt gtatgtaagggcttcttcctgctcatttggcaaactctatttggaggaggcctggtggag ggagccaagaacatcacagtgacagagatcttggccagtatgcccgaccccacccaggac gaggtgcacggggacctgccaggggagcctaggactggggaggagcaggaggcaggaggc gtgactgaccaaatggacacaggcggtggagaggaggaggaggtggacaaccaagacaag gaaggtggggggccaccacgcattgatgctccaggaggacttggtgacatgggaattgag gccactgttgagcctcctactcctgagggtactcctttgaccaggaggaaacagcaacca gaggagggtgctgctgcagctgctgatggccaagctgctgaacctgctcctgctcctgcc atagaggagccccctccagagcctgagaaggccgacactgaaaatggagagaaggctgag aaggaagccgagaccaaagaggaggagaaacaggaggaaccgaaggaaaagaaggccaag gataagaaaaataagaaacaacaccgggagcaagggttccaactctggactgagctggac atccaaagaaacaaattcttgaactacctctctcggaacttttacaatctgcgttttctg gcactgttcattgcatttgctctaaacttcattctactcttctacaaggtgtcggacagc ccccctggagaaggtgatgaggtggagggctctggcatgtttgagggctcgggggtgggg gcgctgtttgagggcagtgggctgtttgagggctcagcagaagagatggagggatctggt ggggatgaaggaggagacgacgaggaggaggaggagggcccagtctacttcttcttggag gagagcactggctacatgcagcccaccctcacattcctggccgccctgcacacagtcatc gccttcctctgcatcatcggctacaactgtctaaagatccctctggtgatctttaagagg gagaaggagctggccaggaagctggagtttgatggtctttacatcacagagcagcctgag gatgatgacatcaaaggtcaatgggacagactggtcctcaacacaccttctttcccaaac aactactgggacaagtttgtcaagcgaaaggtcctggataagtatggagacatttacggc agagagaggatcgcagagcttttaggaatggatttagcctcgttggacgtcagtcaacaa accgataagaagccggaggaaccagacaattccacgttggcctggtgtacatctattgac tttaagtaccagatctggaaatgtggagttgtgttcacagacgggacttttctctatctc tgttggtacacgatcatgtccttgcttggacattacaacaacttcttctatgcctgtcac ttgctggacatagccatcggtgtgaaggatctgcgtactatcctgtcctctgtcacccac aatgggaaacagctcatgatgacattgggcttgttggcagtggtggtgtatctctacact gtagtggcctttatcttcttccgcaagttttacaacaagagtgaagatgaggatgagccg gatatgaaatgtgacgacatgatgacttgctacctcttccacatgtacgtgggcgtgcgt gctggcggtggcataggggacgagatcgaggacccggcgggagacgtgtacgagctctac cgggtggtctttgacatcaccttcttcttctttgtcattgtcatcctgttggccatcatc cagggtctgatcattgacgccttcggagagctccgagaccaacaagagcaggttaaggaa gacatggagaccaagtgcttcatctgtggaattggaagcgactactttgatacgacgccg cacggcttcgagacccacaccctggaggaacacaacttggccaactacatgttcttctta atgtacctcatcaacaaagatgagacggagcacactggccaggagtcatatgtgtggaag atgtaccaggagcgagcgtgggacttcttccctgctggggactgtttcaggaagcaatat gaggatcagcttgcataa

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